CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia J He, Y Chen, M Farzan, H Choe, A Ohagen, S Gartner, J Busciglio, ... Nature 385 (6617), 645-649, 1997 | 1170 | 1997 |
ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-κB X Yang, Y Chen, D Gabuzda Journal of Biological Chemistry 274 (39), 27981-27988, 1999 | 237 | 1999 |
Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab G Scapin, X Yang, WW Prosise, M McCoy, P Reichert, JM Johnston, ... Nature structural & molecular biology 22 (12), 953-958, 2015 | 230 | 2015 |
Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway X Yang, D Gabuzda Journal of virology 73 (4), 3460-3466, 1999 | 199 | 1999 |
Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography P Orth, L Xiao, LD Hernandez, P Reichert, PR Sheth, M Beaumont, ... Journal of biological chemistry 289 (26), 18008-18021, 2014 | 149 | 2014 |
Phosphorylation of Vif and Its Role in HIV-1 Replication (∗) X Yang, J Goncalves, D Gabuzda Journal of Biological Chemistry 271 (17), 10121-10129, 1996 | 138 | 1996 |
Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein X Yang, D Gabuzda Journal of Biological Chemistry 273 (45), 29879-29887, 1998 | 126 | 1998 |
Simultaneous monitoring of oxidation, deamidation, isomerization, and glycosylation of monoclonal antibodies by liquid chromatography-mass spectrometry method with ultrafast … Y Wang, X Li, YH Liu, D Richardson, H Li, M Shameem, X Yang MAbs 8 (8), 1477-1486, 2016 | 110 | 2016 |
Developability studies before initiation of process development: improving manufacturability of monoclonal antibodies X Yang, W Xu, S Dukleska, S Benchaar, S Mengisen, V Antochshuk, ... MAbs 5 (5), 787-794, 2013 | 110 | 2013 |
Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits reverse transcription and viral replication J Goncalves, F Silva, A Freitas-Vieira, M Santa-Marta, R Malhó, X Yang, ... Journal of Biological Chemistry 277 (35), 32036-32045, 2002 | 102 | 2002 |
Biological activity of human immunodeficiency virus type 1 Vif requires membrane targeting by C-terminal basic domains J Goncalves, B Shi, X Yang, D Gabuzda Journal of virology 69 (11), 7196-7204, 1995 | 83 | 1995 |
A small plasmid, pCA2. 4, from the cyanobacterium Synechocystis sp. strain PCC 6803 encodes a rep protein and replicates by a rolling circle mechanism X Yang, BA McFadden Journal of bacteriology 175 (13), 3981-3991, 1993 | 71 | 1993 |
Comprehensive analysis of the therapeutic IgG4 antibody pembrolizumab: hinge modification blocks half molecule exchange in vitro and in vivo X Yang, F Wang, Y Zhang, L Wang, S Antonenko, S Zhang, YW Zhang, ... Journal of Pharmaceutical Sciences 104 (12), 4002-4014, 2015 | 43 | 2015 |
Association between Modic changes, disc degeneration, and neck pain in the cervical spine: a systematic review of literature X Yang, DSA Karis, CLA Vleggeert-Lankamp The Spine Journal 20 (5), 754-764, 2020 | 40 | 2020 |
Analysis of monoclonal antibody oxidation by simple mixed mode chromatography JA Pavon, X Li, S Chico, U Kishnani, S Soundararajan, J Cheung, H Li, ... Journal of Chromatography A 1431, 154-165, 2016 | 40 | 2016 |
The complete DNA sequence and replication analysis of the plasmid pCB2. 4 from the cyanobacterium Synechocystis PCC 6803 X Yang, BA McFadden Plasmid 31 (2), 131-137, 1994 | 39 | 1994 |
Epitopes and mechanism of action of the Clostridium difficile toxin A-neutralizing antibody actoxumab LD Hernandez, HK Kroh, E Hsieh, X Yang, M Beaumont, PR Sheth, ... Journal of molecular biology 429 (7), 1030-1044, 2017 | 38 | 2017 |
Enlarging the repertoire of therapeutic monoclonal antibodies platforms: domesticating half molecule exchange to produce stable IgG4 and IgG1 bispecific antibodies X Yang, A Ambrogelly Current opinion in biotechnology 30, 225-229, 2014 | 36 | 2014 |
Analysis and purification of IgG4 bispecific antibodies by a mixed-mode chromatography X Yang, Y Zhang, F Wang, LJ Wang, D Richardson, M Shameem, ... Analytical biochemistry 484, 173-179, 2015 | 32 | 2015 |
Ultrafast and high-throughput N-glycan analysis for monoclonal antibodies X Yang, SM Kim, R Ruzanski, Y Chen, S Moses, WL Ling, X Li, SC Wang, ... MAbs 8 (4), 706-717, 2016 | 28 | 2016 |