| Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells T Kiyono, SA Foster, JI Koop, JK McDougall, DA Galloway, AJ Klingelhutz Nature 396 (6706), 84-88, 1998 | 1647 | 1998 |
| Telomerase activation by the E6 gene product of human papillomavirus type 16 AJ Klingelhutz, SA Foster, JK McDougall nature 380 (6569), 79-82, 1996 | 1181 | 1996 |
| Enhanced radiation sensitivity in HPV-positive head and neck cancer RJ Kimple, MA Smith, GC Blitzer, AD Torres, JA Martin, RZ Yang, CR Peet, ... Cancer research 73 (15), 4791-4800, 2013 | 432 | 2013 |
| Papillomavirus E6 oncoproteins SBV Pol, AJ Klingelhutz Virology 445 (1-2), 115-137, 2013 | 419 | 2013 |
| Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients S Agarwal, YH Loh, EM McLoughlin, J Huang, IH Park, JD Miller, H Huo, ... Nature 464 (7286), 292-296, 2010 | 363 | 2010 |
| Cigarette smoke induces cellular senescence T Nyunoya, MM Monick, A Klingelhutz, TO Yarovinsky, JR Cagley, ... American journal of respiratory cell and molecular biology 35 (6), 681-688, 2006 | 305 | 2006 |
| Cellular transformation by human papillomaviruses: lessons learned by comparing high-and low-risk viruses AJ Klingelhutz, A Roman Virology 424 (2), 77-98, 2012 | 243 | 2012 |
| Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells AJ Klingelhutz, SA Barber, PP Smith, K Dyer, JK Mcdougall Molecular and cellular biology 14 (2), 961-969, 1994 | 232 | 1994 |
| Genetic and epigenetic changes in human epithelial cells immortalized by telomerase DG Farwell, KA Shera, JI Koop, GA Bonnet, CP Matthews, GW Reuther, ... The American journal of pathology 156 (5), 1537-1547, 2000 | 228 | 2000 |
| Development of cystic fibrosis and noncystic fibrosis airway cell lines J Zabner, P Karp, M Seiler, SL Phillips, CJ Mitchell, M Saavedra, M Welsh, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 284 (5 …, 2003 | 220 | 2003 |
| Epstein-Barr virus latent membrane protein 2A activates β-catenin signaling in epithelial cells JA Morrison, AJ Klingelhutz, N Raab-Traub Journal of virology 77 (22), 12276-12284, 2003 | 216 | 2003 |
| Human papillomavirus type 16 E6 activates NF-κB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner MA James, JH Lee, AJ Klingelhutz Journal of virology 80 (11), 5301-5307, 2006 | 207 | 2006 |
| Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence JA Martin, AJ Klingelhutz, F Moussavi-Harami, JA Buckwalter The Journals of Gerontology Series A: Biological Sciences and Medical …, 2004 | 164 | 2004 |
| The PDZ binding motif of human papillomavirus type 16 E6 induces PTPN13 loss, which allows anchorage-independent growth and synergizes with ras for invasive growth WC Spanos, A Hoover, GF Harris, S Wu, GL Strand, ME Anderson, ... Journal of virology 82 (5), 2493-2500, 2008 | 156 | 2008 |
| The role of telomeres in the ageing of human skin EM Buckingham, AJ Klingelhutz Experimental dermatology 20 (4), 297-302, 2011 | 134 | 2011 |
| SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis Y Zhang, L Xie, SK Gunasekar, D Tong, A Mishra, WJ Gibson, C Wang, ... Nature cell biology 19 (5), 504-517, 2017 | 132 | 2017 |
| The DCC gene suppresses the malignant phenotype of transformed human epithelial cells. AJ Klingelhutz, L Hedrick, KR Cho, JK McDougall Oncogene 10 (8), 1581-1586, 1995 | 127 | 1995 |
| The Innate Immune System Is Activated by Stimulation of Vaginal Epithelial Cells with Staphylococcus aureus and Toxic Shock Syndrome Toxin 1 ML Peterson, K Ault, MJ Kremer, AJ Klingelhutz, CC Davis, CA Squier, ... Infection and immunity 73 (4), 2164-2174, 2005 | 122 | 2005 |
| Microarray analysis identifies differentiation-associated genes regulated by human papillomavirus type 16 E6 CL Duffy, SL Phillips, AJ Klingelhutz Virology 314 (1), 196-205, 2003 | 112 | 2003 |
| Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery AJ Klingelhutz, FA Gourronc, A Chaly, DA Wadkins, AJ Burand, ... Scientific reports 8 (1), 523, 2018 | 111 | 2018 |
Francoise GourroncVerified email at uiowa.edu
