| Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ... Cell metabolism 19 (3), 407-417, 2014 | 1058 | 2014 |
| The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance C Lee, J Zeng, BG Drew, T Sallam, A Martin-Montalvo, J Wan, SJ Kim, ... Cell metabolism 21 (3), 443-454, 2015 | 590 | 2015 |
| Effects of sex, strain, and energy intake on hallmarks of aging in mice SJ Mitchell, J Madrigal-Matute, M Scheibye-Knudsen, E Fang, M Aon, ... Cell metabolism 23 (6), 1093-1112, 2016 | 411 | 2016 |
| Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers LJ Cobb, C Lee, J Xiao, K Yen, RG Wong, HK Nakamura, HH Mehta, ... Aging (Albany NY) 8 (4), 796, 2016 | 235 | 2016 |
| Low insulin‐like growth factor‐1 level predicts survival in humans with exceptional longevity S Milman, G Atzmon, DM Huffman, J Wan, JP Crandall, P Cohen, ... Aging cell 13 (4), 769-771, 2014 | 230 | 2014 |
| Mitochondrially derived peptides as novel regulators of metabolism SJ Kim, J Xiao, J Wan, P Cohen, K Yen The Journal of physiology 595 (21), 6613-6621, 2017 | 170 | 2017 |
| The mitochondrial-derived peptide humanin protects RPE cells from oxidative stress, senescence, and mitochondrial dysfunction PG Sreekumar, K Ishikawa, C Spee, HH Mehta, J Wan, K Yen, P Cohen, ... Investigative ophthalmology & visual science 57 (3), 1238-1253, 2016 | 167 | 2016 |
| Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning. J Wan, J Shi, L Hui, D Wu, X Jin, N Zhao, W Huang, Z Xia, G Hu Environmental health perspectives 110 (12), 1213-1218, 2002 | 144 | 2002 |
| Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract SA Ritz, J Wan, D Diaz-Sanchez American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (1 …, 2007 | 135 | 2007 |
| Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice YK Oh, AR Bachar, DG Zacharias, SG Kim, J Wan, LJ Cobb, LO Lerman, ... Atherosclerosis 219 (1), 65-73, 2011 | 125 | 2011 |
| Mitochondrial peptides modulate mitochondrial function during cellular senescence SJ Kim, HH Mehta, J Wan, C Kuehnemann, J Chen, JF Hu, AR Hoffman, ... Aging (Albany NY) 10 (6), 1239, 2018 | 123 | 2018 |
| Circulating humanin levels are associated with preserved coronary endothelial function RJ Widmer, AJ Flammer, J Herrmann, M Rodriguez-Porcel, J Wan, ... American Journal of Physiology-Heart and Circulatory Physiology 304 (3 …, 2013 | 122 | 2013 |
| IGFBP-3 is a metastasis suppression gene in prostate cancer HH Mehta, Q Gao, C Galet, V Paharkova, J Wan, J Said, JJ Sohn, ... Cancer research 71 (15), 5154-5163, 2011 | 106 | 2011 |
| Protein restriction cycles reduce IGF‐1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model E Parrella, T Maxim, F Maialetti, L Zhang, J Wan, M Wei, P Cohen, ... Aging cell 12 (2), 257-268, 2013 | 95 | 2013 |
| Phase II prospective randomized trial of a low-fat diet with fish oil supplementation in men undergoing radical prostatectomy WJ Aronson, N Kobayashi, RJ Barnard, S Henning, M Huang, PM Jardack, ... Cancer prevention research 4 (12), 2062-2071, 2011 | 90 | 2011 |
| Effects of air pollution on mitochondrial function, mitochondrial DNA methylation, and mitochondrial peptide expression CV Breton, AY Song, J Xiao, SJ Kim, HH Mehta, J Wan, K Yen, C Sioutas, ... Mitochondrion 46, 22-29, 2019 | 85 | 2019 |
| IGF‐I regulates the age‐dependent signaling peptide humanin C Lee, J Wan, B Miyazaki, Y Fang, J Guevara‐Aguirre, K Yen, V Longo, ... Aging Cell 13 (5), 958-961, 2014 | 83 | 2014 |
| The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan K Yen, HH Mehta, SJ Kim, YH Lue, J Hoang, N Guerrero, J Port, Q Bi, ... Aging (Albany NY) 12 (12), 11185, 2020 | 81 | 2020 |
| Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans K Yen, J Wan, HH Mehta, B Miller, A Christensen, ME Levine, ... Scientific reports 8 (1), 14212, 2018 | 81 | 2018 |
| Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction Q Qin, S Delrio, J Wan, RJ Widmer, P Cohen, LO Lerman, A Lerman International journal of cardiology 254, 23-27, 2018 | 79 | 2018 |
