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Chuanyue Wu
Chuanyue Wu
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Breaking the Integrin Hinge: A DEFINED STRUCTURAL CONSTRAINT REGULATES INTEGRIN SIGNALING (∗)
PE Hughes, F Diaz-Gonzalez, L Leong, C Wu, JA McDonald, SJ Shattil, ...
Journal of Biological Chemistry 271 (12), 6571-6574, 1996
7581996
Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes
C Wu, S Dedhar
The Journal of cell biology 155 (4), 505-510, 2001
5862001
Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis
Y Li, J Yang, C Dai, C Wu, Y Liu
The Journal of clinical investigation 112 (4), 503-516, 2003
5832003
Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrix
C Wu, VM Keivenst, TE O'Toole, JA McDonald, MH Ginsberg
Cell 83 (5), 715-724, 1995
4551995
Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation
Y Tu, S Wu, X Shi, K Chen, C Wu
Cell 113 (1), 37-47, 2003
4192003
Kindlin-2 (Mig-2): a co-activator of β3 integrins
YQ Ma, J Qin, C Wu, EF Plow
The Journal of cell biology 181 (3), 439-446, 2008
4102008
Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity
C Wu, SY Keightley, C Leung-Hagesteijn, G Radeva, M Coppolino, ...
Journal of Biological Chemistry 273 (1), 528-536, 1998
4021998
The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells
Y Tu, F Li, S Goicoechea, C Wu
Molecular and cellular biology 19 (3), 2425-2434, 1999
4001999
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading
Y Tu, Y Huang, Y Zhang, Y Hua, C Wu
The Journal of cell biology 153 (3), 585-598, 2001
2892001
Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways
Y Tu, F Li, C Wu
Molecular biology of the cell 9 (12), 3367-3382, 1998
2801998
Kindlins: essential regulators of integrin signalling and cell–matrix adhesion
H Larjava, EF Plow, C Wu
EMBO reports 9 (12), 1203-1208, 2008
2642008
Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated …
F Li, Y Zhang, C Wu
Journal of cell science 112 (24), 4589-4599, 1999
2531999
PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival
T Fukuda, K Chen, X Shi, C Wu
Journal of Biological Chemistry 278 (51), 51324-51333, 2003
2512003
Assembly of extracellular matrix
DF Mosher, J Sottile, C Wu, JA McDonald
Current opinion in cell biology 4 (5), 810-818, 1992
2501992
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites
Y Zhang, K Chen, Y Tu, A Velyvis, Y Yang, J Qin, C Wu
Journal of cell science 115 (24), 4777-4786, 2002
2142002
The alpha 5 beta 1 integrin fibronectin receptor, but not the alpha 5 cytoplasmic domain, functions in an early and essential step in fibronectin matrix assembly.
C Wu, JS Bauer, RL Juliano, JA McDonald
Journal of Biological Chemistry 268 (29), 21883-21888, 1993
203*1993
ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling
Y Qian, X Zhong, DC Flynn, JZ Zheng, M Qiao, C Wu, S Dedhar, X Shi, ...
Oncogene 24 (19), 3154-3165, 2005
1992005
The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility
X Shi, YQ Ma, Y Tu, K Chen, S Wu, K Fukuda, J Qin, EF Plow, C Wu
Journal of Biological Chemistry 282 (28), 20455-20466, 2007
1962007
Focal adhesion: a focal point in current cell biology and molecular medicine
C Wu
Cell adhesion & migration 1 (1), 13-18, 2007
1962007
Inhibition of integrin-linked kinase blocks podocyte epithelial–mesenchymal transition and ameliorates proteinuria
YS Kang, Y Li, C Dai, LP Kiss, C Wu, Y Liu
Kidney International 78 (4), 363-373, 2010
1942010
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