Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease H Girouard, C Iadecola Journal of applied physiology 100 (1), 328-335, 2006 | 1540 | 2006 |
Sex differences in Alzheimer disease—the gateway to precision medicine MT Ferretti, MF Iulita, E Cavedo, PA Chiesa, A Schumacher Dimech, ... Nature Reviews Neurology 14 (8), 457-469, 2018 | 664 | 2018 |
Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction H Girouard, AD Bonev, RM Hannah, A Meredith, RW Aldrich, MT Nelson Proceedings of the National Academy of Sciences 107 (8), 3811-3816, 2010 | 357 | 2010 |
Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain L Park, J Anrather, H Girouard, P Zhou, C Iadecola Journal of Cerebral Blood Flow & Metabolism 27 (12), 1908-1918, 2007 | 317 | 2007 |
NMDA receptor activation increases free radical production through nitric oxide and NOX2 H Girouard, G Wang, EF Gallo, J Anrather, P Zhou, VM Pickel, C Iadecola Journal of Neuroscience 29 (8), 2545-2552, 2009 | 289 | 2009 |
Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase–derived radicals K Kazama, J Anrather, P Zhou, H Girouard, K Frys, TA Milner, C Iadecola Circulation research 95 (10), 1019-1026, 2004 | 287 | 2004 |
Oxidative stress in hypertension J de Champlain, R Wu, H Girouard, M Karas, A El Midaoui, MA Laplante, ... Clinical and experimental Hypertension 26 (7-8), 593-601, 2004 | 236 | 2004 |
Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II H Girouard, L Park, J Anrather, P Zhou, C Iadecola Arteriosclerosis, thrombosis, and vascular biology 27 (2), 303-309, 2007 | 170 | 2007 |
Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2–derived radicals H Girouard, L Park, J Anrather, P Zhou, C Iadecola Arteriosclerosis, thrombosis, and vascular biology 26 (4), 826-832, 2006 | 170 | 2006 |
Remote control of the permeability of the blood–brain barrier by magnetic heating of nanoparticles: a proof of concept for brain drug delivery SN Tabatabaei, H Girouard, AS Carret, S Martel Journal of Controlled Release 206, 49-57, 2015 | 148 | 2015 |
Vasorelaxant effects of the chronic treatment with melatonin on mesenteric artery and aorta of spontaneously hypertensive rats H Girouard, C Chulak, M Lejossec, D Lamontagne, J de Champlain Journal of hypertension 19 (8), 1369-1377, 2001 | 132 | 2001 |
The key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction L Park, G Wang, J Moore, H Girouard, P Zhou, J Anrather, C Iadecola Nature communications 5 (1), 5318, 2014 | 120 | 2014 |
The complex contribution of NOS interneurons in the physiology of cerebrovascular regulation S Duchemin, M Boily, N Sadekova, H Girouard Frontiers in neural circuits 6, 51, 2012 | 103 | 2012 |
Arterial stiffness, cognitive impairment and dementia: confounding factor or real risk? MF Iulita, A Noriega de la Colina, H Girouard Journal of Neurochemistry 144 (5), 527-548, 2018 | 99 | 2018 |
Treatment by N-acetylcysteine and melatonin increases cardiac baroreflex and improves antioxidant reserve H Girouard, C Denault, C Chulak, J Champlain American journal of hypertension 17 (10), 947-954, 2004 | 95 | 2004 |
Effects of chronic N-acetylcysteine treatment on the actions of peroxynitrite on aortic vascular reactivity in hypertensive rats A Cabassi, EC Dumont, H Girouard, JF Bouchard, M Le Jossec, ... Journal of hypertension 19 (7), 1233-1244, 2001 | 93 | 2001 |
Chronic antioxidant treatment improves sympathetic functions and β-adrenergic pathway in the spontaneously hypertensive rats H Girouard, C Chulak, M LeJossec, D Lamontagne, J de Champlain Journal of hypertension 21 (1), 179-188, 2003 | 92 | 2003 |
N-acetylcysteine improves nitric oxide and α-adrenergic pathways in mesenteric beds of spontaneously hypertensive rats H Girouard, C Chulak, L Wu, M Lejossec, J De Champlain American journal of hypertension 16 (7), 577-584, 2003 | 77 | 2003 |
Chronic perfusion of angiotensin II causes cognitive dysfunctions and anxiety in mice S Duchemin, E Belanger, R Wu, G Ferland, H Girouard Physiology & behavior 109, 63-68, 2013 | 69 | 2013 |
iNOS-derived NO and nox2-derived superoxide confer tolerance to excitotoxic brain injury through peroxynitrite T Kawano, A Kunz, T Abe, H Girouard, J Anrather, P Zhou, C Iadecola Journal of Cerebral Blood Flow & Metabolism 27 (8), 1453-1462, 2007 | 64 | 2007 |