PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression K Chiang, AE Zielinska, AM Shaaban, MP Sanchez-Bailon, J Jarrold, ... Cell reports 21 (12), 3498-3513, 2017 | 174 | 2017 |
PRMT5-dependent methylation of the TIP60 coactivator RUVBL1 is a key regulator of homologous recombination TL Clarke, MP Sanchez-Bailon, K Chiang, JJ Reynolds, J Herrero-Ruiz, ... Molecular cell 65 (5), 900-916. e7, 2017 | 134 | 2017 |
Cross-talk between lysine-modifying enzymes controls site-specific DNA amplifications S Mishra, C Van Rechem, S Pal, TL Clarke, D Chakraborty, SD Mahan, ... Cell 174 (4), 803-817. e16, 2018 | 53 | 2018 |
Histone Lysine Methylation Dynamics Control EGFR DNA Copy-Number Amplification TL Clarke, R Tang, D Chakraborty, C Van Rechem, F Ji, S Mishra, A Ma, ... Cancer discovery 10 (2), 306-325, 2020 | 37 | 2020 |
Identifying novel protein interactions: Proteomic methods, optimisation approaches and data analysis pipelines DG Carneiro, T Clarke, CC Davies, D Bailey Methods 95, 46-54, 2016 | 35 | 2016 |
DNA repair as a shared hallmark in cancer and ageing TL Clarke, R Mostoslavsky Molecular Oncology 16 (18), 3352-3379, 2022 | 24 | 2022 |
Predicting response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer with serum biomarkers TL Clarke, DA White, ME Osborne, AM Shaw, NJ Smart, IR Daniels The Annals of The Royal College of Surgeons of England 99 (5), 373-377, 2017 | 19 | 2017 |
Assessing kinetics and recruitment of DNA repair factors using high content screens B Martinez-Pastor, GG Silveira, TL Clarke, D Chung, Y Gu, C Cosentino, ... Cell Reports 37 (13), 110176, 2021 | 10 | 2021 |
Resveratrol: Friend or Foe? TL Clarke, R Mostoslavsky Molecular Cell 79 (5), 705-707, 2020 | 2 | 2020 |
A novel role for the arginine methyltransferase PRMT5 in the DNA damage response and implications for cancer therapy TL Clarke University of Birmingham, 2017 | | 2017 |