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Mohamed Amine Bouhlel
Mohamed Amine Bouhlel
University of Lille North of France
Adresse e-mail validée de inserm.fr
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PPARγ activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
MA Bouhlel, B Derudas, E Rigamonti, R Dièvart, J Brozek, S Haulon, ...
Cell metabolism 6 (2), 137-143, 2007
15632007
Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXRα pathways
G Chinetti-Gbaguidi, M Baron, MA Bouhlel, J Vanhoutte, C Copin, Y Sebti, ...
Circulation research 108 (8), 985-995, 2011
4412011
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma
B Lamprecht, K Walter, S Kreher, R Kumar, M Hummel, D Lenze, ...
Nature medicine 16 (5), 571-579, 2010
3842010
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages
E Rigamonti, L Helin, S Lestavel, AL Mutka, M Lepore, C Fontaine, ...
Circulation research 97 (7), 682-689, 2005
1622005
Unlike PPARγ, PPARα or PPARβ/δ activation does not promote human monocyte differentiation toward alternative macrophages
MA Bouhlel, J Brozek, B Derudas, C Zawadzki, B Jude, B Staels, ...
Biochemical and biophysical research communications 386 (3), 459-462, 2009
722009
Peroxisome proliferator‐activated receptors–from active regulators of macrophage biology to pharmacological targets in the treatment of cardiovascular disease
MA Bouhlel, B Staels, G Chinetti‐Gbaguidi
Journal of internal medicine 263 (1), 28-42, 2008
672008
11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis
T Kipari, PWF Hadoke, J Iqbal, TY Man, E Miller, AE Coutinho, Z Zhang, ...
The FASEB journal 27 (4), 1519, 2013
652013
New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors
C Gros, L Fleury, V Nahoum, C Faux, S Valente, D Labella, F Cantagrel, ...
Journal of Biological Chemistry 290 (10), 6293-6302, 2015
632015
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma
S Kreher, MA Bouhlel, P Cauchy, B Lamprecht, S Li, M Grau, F Hummel, ...
Proceedings of the National Academy of Sciences 111 (42), E4513-E4522, 2014
622014
Rational design of bisubstrate-type analogues as inhibitors of DNA methyltransferases in cancer cells
L Halby, Y Menon, E Rilova, D Pechalrieu, V Masson, C Faux, MA Bouhlel, ...
Journal of Medicinal Chemistry 60 (11), 4665-4679, 2017
472017
Targeting transcription factor binding to DNA by competing with DNA binders as an approach for controlling gene expression
M Amine Bouhlel, M Lambert, MH David-Cordonnier
Current topics in medicinal chemistry 15 (14), 1323-1358, 2015
452015
Visfatin is induced by peroxisome proliferator‐activated receptor gamma in human macrophages
TH Mayi, C Duhem, C Copin, MA Bouhlel, E Rigamonti, F Pattou, B Staels, ...
The FEBS journal 277 (16), 3308-3320, 2010
442010
Peroxisome Proliferator–Activated Receptor-γ Activation Induces 11β-Hydroxysteroid Dehydrogenase Type 1 Activity in Human Alternative Macrophages
G Chinetti-Gbaguidi, MA Bouhlel, C Copin, C Duhem, B Derudas, B Neve, ...
Arteriosclerosis, thrombosis, and vascular biology 32 (3), 677-685, 2012
432012
The Function of the Conserved Regulatory Element within the Second Intron of the Mammalian Csf1r Locus
KA Sauter, MA Bouhlel, J O’Neal, DP Sester, H Tagoh, RM Ingram, ...
PloS one 8 (1), e54935, 2013
332013
Perilipin, a potential substitute for adipophilin in triglyceride storage in human macrophages
G Larigauderie, MA Bouhlel, C Furman, M Jaye, JC Fruchart, M Rouis
Atherosclerosis 189 (1), 142-148, 2006
332006
Differential regulation of sense and antisense promoter activity at the Csf1R locus in B cells by the transcription factor PAX5
RM Ingram, S Valeaux, N Wilson, MA Bouhlel, D Clarke, I Krüger, D Kulu, ...
Experimental hematology 39 (7), 730-740. e2, 2011
82011
Glitazones in the treatment of cardiovascular risk factors
MA Bouhlel, G Chinetti‐Gbaguidi, B Staels
Fundamental & clinical pharmacology 21, 7-13, 2007
52007
HOXA9 transcription factor as a target in acute myeloid leukemia: Transcription, cellular and in vivo consequences of its invalidation
M Lambert, S Jambon, S Depauw, MA Bouhlel, M Figeac, ...
European Journal of Cancer 1 (69), S23, 2016
12016
Targeting transcription factor at the DNA binding level: Inhibition of ERG and FLI1 binding to their consensus DNA binding site
R Nhili, S Depauw, M Lambert, MA Bouhlel, MH David-Cordonnier
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 34, S16-S16, 2014
2014
The Function of the Conserved Regulatory Element within the Second Intron of the
KA Sauter, MA Bouhlel, J O’Neal, DP Sester, H Tagoh
2013
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