Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress U Seifert, LP Bialy, F Ebstein, D Bech-Otschir, A Voigt, F Schröter, ... Cell 142 (4), 613-624, 2010 | 654 | 2010 |
Physiological responses to mixing in large scale bioreactors SO Enfors, M Jahic, A Rozkov, B Xu, M Hecker, B Jürgen, E Krüger, ... Journal of biotechnology 85 (2), 175-185, 2001 | 528 | 2001 |
Proteasomal degradation is transcriptionally controlled by TCF11 via an ERAD-dependent feedback loop J Steffen, M Seeger, A Koch, E Krüger Molecular cell 40 (1), 147-158, 2010 | 375 | 2010 |
Inhibition of proteasome activity induces concerted expression of proteasome genes and de novo formation of Mammalian proteasomes S Meiners, D Heyken, A Weller, A Ludwig, K Stangl, PM Kloetzel, ... Journal of Biological Chemistry 278 (24), 21517-21525, 2003 | 365 | 2003 |
IFN-γ-induced immune adaptation of the proteasome system is an accelerated and transient response S Heink, D Ludwig, PM Kloetzel, E Krüger Proceedings of the National Academy of Sciences 102 (26), 9241-9246, 2005 | 353 | 2005 |
Interferon‐γ, the functional plasticity of the ubiquitin–proteasome system, and MHC class I antigen processing B Strehl, U Seifert, E Krüger, S Heink, U Kuckelkorn, PM Kloetzel Immunological reviews 207 (1), 19-30, 2005 | 329 | 2005 |
Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production A Brehm, Y Liu, A Sheikh, B Marrero, E Omoyinmi, Q Zhou, ... The Journal of clinical investigation 125 (11), 4196-4211, 2015 | 291 | 2015 |
Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in … U Gerth, E Krüger, I Derré, T Msadek, M Hecker Molecular microbiology 28 (4), 787-802, 1998 | 236 | 1998 |
The Clp Proteases of Bacillus subtilisAre Directly Involved in Degradation of Misfolded Proteins E Krüger, E Witt, S Ohlmeier, R Hanschke, M Hecker Journal of Bacteriology 182 (11), 3259-3265, 2000 | 207 | 2000 |
Stress induction of clpC in Bacillus subtilis and its involvement in stress tolerance E Krüger, U Völker, M Hecker Journal of bacteriology 176 (11), 3360-3367, 1994 | 174 | 1994 |
Clp-mediated proteolysis in Gram-positive bacteria is autoregulated by the stability of a repressor E Krüger, D Zühlke, E Witt, H Ludwig, M Hecker The EMBO journal 20 (4), 852-863, 2001 | 171 | 2001 |
Monitoring of genes that respond to process‐related stress in large‐scale bioprocesses T Schweder, E Krüger, B Xu, B Jürgen, G Blomsten, SO Enfors, M Hecker Biotechnology and bioengineering 65 (2), 151-159, 1999 | 168 | 1999 |
Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7 (β5i) incorporation into 20 S proteasomes E Witt, D Zantopf, M Schmidt, R Kraft, PM Kloetzel, E Krüger Journal of molecular biology 301 (1), 1-9, 2000 | 167 | 2000 |
Emerging roles of immunoproteasomes beyond MHC class I antigen processing F Ebstein, PM Kloetzel, E Krüger, U Seifert Cellular and Molecular Life Sciences 69, 2543-2558, 2012 | 164 | 2012 |
The First Gene of the Bacillus subtilis clpC Operon,ctsR, Encodes a Negative Regulator of Its Own Operon and Other Class III Heat Shock Genes E Krüger, M Hecker Journal of bacteriology 180 (24), 6681-6688, 1998 | 160 | 1998 |
Heterozygous truncating variants in POMP escape nonsense-mediated decay and cause a unique immune dysregulatory syndrome MC Poli, F Ebstein, SK Nicholas, MM de Guzman, LR Forbes, IK Chinn, ... The American Journal of Human Genetics 102 (6), 1126-1142, 2018 | 146 | 2018 |
The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum B Fricke, S Heink, J Steffen, PM Kloetzel, E Krüger EMBO reports 8 (12), 1170-1175, 2007 | 141 | 2007 |
Immunoproteasomes at the interface of innate and adaptive immune responses: two faces of one enzyme E Krüger, PM Kloetzel Current opinion in immunology 24 (1), 77-83, 2012 | 122 | 2012 |
Impairment of immunoproteasome function by β5i/LMP7 subunit deficiency results in severe enterovirus myocarditis E Opitz, A Koch, K Klingel, F Schmidt, S Prokop, A Rahnefeld, M Sauter, ... PLoS pathogens 7 (9), e1002233, 2011 | 111 | 2011 |
Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal α and β subunits GS Apcher, S Heink, D Zantopf, PM Kloetzel, HP Schmid, RJ Mayer, ... FEBS letters 553 (1-2), 200-204, 2003 | 109 | 2003 |