| Contribution of NIH funding to new drug approvals 2010–2016 E Galkina Cleary, JM Beierlein, NS Khanuja, LM McNamee, FD Ledley Proceedings of the National Academy of Sciences 115 (10), 2329-2334, 2018 | 236 | 2018 |
| Highly Efficient Ligands for Dihydrofolate Reductase from Cryptosporidium hominis and Toxoplasma gondii Inspired by Structural Analysis PM Pelphrey, VM Popov, TM Joska, JM Beierlein, ESD Bolstad, ... Journal of medicinal chemistry 50 (5), 940-950, 2007 | 111 | 2007 |
| Synthetic and Crystallographic Studies of a New Inhibitor Series Targeting Bacillus anthracis Dihydrofolate Reductase JM Beierlein, KM Frey, DB Bolstad, PM Pelphrey, TM Joska, AE Smith, ... Journal of medicinal chemistry 51 (23), 7532-7540, 2008 | 48 | 2008 |
| New developments in vaccines, inhibitors of anthrax toxins, and antibiotic therapeutics for Bacillus anthracis J M Beierlein, A C Anderson Current medicinal chemistry 18 (33), 5083-5094, 2011 | 44 | 2011 |
| As technologies for nucleotide therapeutics mature, products emerge JM Beierlein, LM McNamee, FD Ledley Molecular Therapy-Nucleic Acids 9, 379-386, 2017 | 30 | 2017 |
| Landscape of innovation for cardiovascular pharmaceuticals: From basic science to new molecular entities JM Beierlein, LM McNamee, MJ Walsh, KI Kaitin, JA DiMasi, FD Ledley Clinical therapeutics 39 (7), 1409-1425. e20, 2017 | 28 | 2017 |
| NIH's Helping to End Addiction Long-termSM Initiative (NIH HEAL Initiative) Clinical Pain Management Common Data Element Program LD Wandner, AF Domenichiello, J Beierlein, L Pogorzala, G Aquino, ... The Journal of Pain 23 (3), 370-378, 2022 | 25 | 2022 |
| Targeted Mutations of Bacillus anthracis Dihydrofolate Reductase Condense Complex Structure−Activity Relationships JM Beierlein, NG Karri, AC Anderson Journal of medicinal chemistry 53 (20), 7327-7336, 2010 | 18 | 2010 |
| Patterns of innovation in Alzheimer’s disease drug development: a strategic assessment based on technological maturity JM Beierlein, LM McNamee, MJ Walsh, FD Ledley Clinical Therapeutics 37 (8), 1643-1651. e3, 2015 | 17 | 2015 |
| The Solution Structure of Bacillus anthracis Dihydrofolate Reductase Yields Insight into the Analysis of Structure−Activity Relationships for Novel Inhibitors JM Beierlein, L Deshmukh, KM Frey, O Vinogradova, AC Anderson Biochemistry 48 (19), 4100-4108, 2009 | 13 | 2009 |
| NIH Pain Consortium Institute and Center Representatives. NIH’s helping to end addiction Long-term (SM) initiative (NIH HEAL initiative) clinical pain management common data … LD Wandner, AF Domenichiello, J Beierlein, L Pogorzala, G Aquino, ... J Pain 23 (3), 370-8, 2022 | 11 | 2022 |
| Catalytic Asymmetric Aziridination of Benzhydryl Imines and Diazoacetate Esters with BOROX Catalysts from 3, 3′-Disubstituted VANOL Ligands Y Guan, Z Lu, X Yin, A Mohammadlou, RJ Staples, WD Wulff Synthesis 52 (14), 2073-2091, 2020 | 6 | 2020 |
| Critical NIH resources to advance therapies for pain: preclinical screening program and phase II human clinical trial network S Iyengar, SA Woller, R Hommer, J Beierlein, CB Wright, AP Tamiz, ... Neurotherapeutics 17 (3), 932-934, 2020 | 5 | 2020 |
| The NIH HEAL Initiative/National Institute of Neurological Disorders and Stroke Early Phase Pain Investigation Clinical Network Update B Karp, R Hommer, J Barnes, L Sawaki-Adams, MP Lawrence, K Jones, ... NEUROTHERAPEUTICS 19 (4), 1422-1423, 2022 | | 2022 |
| NIH HEAL Initiative: National Institute of Neurological Disorders and Stroke's Early Phase Pain Investigation Clinical Network (EPPIC-Net) C Faraco, R Hommer, J Beierlein, M Peters-Lawrence, CB Wright, BI Karp NEUROPSYCHOPHARMACOLOGY 46 (SUPPL 1), 304-305, 2021 | | 2021 |
| NIH HEAL Initiative: National Institute of Neurological Disorders and Stroke's Early Phase Pain Investigation Clinical Network (EPPIC-Net) J Beierlein, R Hommer, C Wright, BI Karp NEUROTHERAPEUTICS 17 (3), 1320-1320, 2020 | | 2020 |
| NIH HEAL Initiative Programs to Accelerate Development of Non-Addictive Therapeutics for Pain: Preclinical Screening Platform for Pain and Early Phase Pain Investigation … SA Woller, J Beierlein, R Hommer, C Wright, A Tamiz, B Karp, S Iyengar HEADACHE 60, 139-139, 2020 | | 2020 |
| NIH HEAL Initiative: National Institute of Neurological Disorders and Stroke ININDS) programs for accelerated development of novel approaches to pain management (1625) B Karp, R Hommer, A Tamiz, C Wright, J Beierlein, S Woller, S Iyengar Neurology 94 (15 Supplement), 2020 | | 2020 |
| Structural and Synthetic Studies into Novel Antifolates Targeting Bacillus anthracis Dihydrofolate Reductase JM Beierlein University of Connecticut, 2011 | | 2011 |
| Full wwPDB NMR Structure Validation Report i○ L Deshmukh, O Vinogradova, A Makriyannis, E Tiburu, S Tyukhtenko, ... | | |
