| Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death L Chen, B Xu, L Liu, Y Luo, H Zhou, W Chen, T Shen, X Han, CD Kontos, ... Free Radical Biology and Medicine 50 (5), 624-632, 2011 | 267 | 2011 |
| Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells L Chen, B Xu, L Liu, Y Luo, J Yin, H Zhou, W Chen, T Shen, X Han, ... Laboratory Investigation 90 (5), 762-773, 2010 | 266 | 2010 |
| The role of Cdc25A in the regulation of cell proliferation and apoptosis T Shen, S Huang Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2012 | 225 | 2012 |
| Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network B Xu, S Chen, Y Luo, Z Chen, L Liu, H Zhou, W Chen, T Shen, X Han, ... PloS one 6 (4), e19052, 2011 | 216 | 2011 |
| Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity L Liu, Y Luo, L Chen, T Shen, B Xu, W Chen, H Zhou, X Han, S Huang Journal of Biological Chemistry 285 (49), 38362-38373, 2010 | 158 | 2010 |
| The antitumor activity of the fungicide ciclopirox H Zhou, T Shen, Y Luo, L Liu, W Chen, B Xu, X Han, J Pang, CA Rivera, ... International journal of cancer 127 (10), 2467-2477, 2010 | 121 | 2010 |
| Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway H Zhou, T Shen, C Shang, Y Luo, L Liu, J Yan, Y Li, S Huang Oncotarget 5 (20), 10140-10150, 2014 | 92 | 2014 |
| Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells W Chen, L Liu, Y Luo, Y Odaka, S Awate, H Zhou, T Shen, S Zheng, Y Lu, ... Cancer Prevention Research 5 (5), 778-787, 2012 | 89 | 2012 |
| Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells X Han, B Xu, CS Beevers, Y Odaka, L Chen, L Liu, Y Luo, H Zhou, ... Carcinogenesis, bgs029, 2012 | 80 | 2012 |
| Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression Y Luo, L Liu, D Rogers, W Su, Y Odaka, H Zhou, W Chen, T Shen, ... Neoplasia 14 (3), 228-237, 2012 | 76 | 2012 |
| Preclinical Modeling of KIF5B–RET Fusion Lung Adenocarcinoma Q Huang, VE Schneeberger, N Luetteke, C Jin, R Afzal, MM Budzevich, ... Molecular cancer therapeutics 15 (10), 2521-2529, 2016 | 72 | 2016 |
| Tentative association of the serotonin transporter with schizophrenia and unipolar depression but not with bipolar disorder in Han Chinese. W Liu, N Gu, G Feng, S Li, S Bai, J Zhang, T Shen, H Xue, G Breen, ... Pharmacogenetics and Genomics 9 (4), 491-495, 1999 | 71 | 1999 |
| Drug resistance profiles of mutations in the RET kinase domain X Liu, T Shen, BHM Mooers, F Hilberg, J Wu British journal of pharmacology, 2018 | 65 | 2018 |
| Overexpression of major CDKN3 transcripts is associated with poor survival in lung adenocarcinoma C Fan, L Chen, Q Huang, T Shen, EA Welsh, JK Teer, J Cai, WD Cress, ... British journal of cancer, 2015 | 65 | 2015 |
| Repositioning the old fungicide ciclopirox for new medical uses T Shen, S Huang Current pharmaceutical design 22 (28), 4443-4450, 2016 | 58 | 2016 |
| Association between angiotensin-converting enzyme gene and late onset Alzheimer's disease in Han Chinese JD Yang, G Feng, J Zhang, ZX Lin, T Shen, G Breen, D St Clair, L He Neuroscience letters 295 (1), 41-44, 2000 | 56 | 2000 |
| Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway L Liu, L Chen, Y Luo, W Chen, H Zhou, B Xu, X Han, T Shen, S Huang PloS one 5 (5), e10578, 2010 | 53 | 2010 |
| Association of APOE gene with schizophrenia in Chinese: a possible risk factor in times of malnutrition W Liu, G Breen, J Zhang, S Li, N Gu, G Feng, S Bai, T Shen, A Yu, H Xue, ... Schizophrenia research 62 (3), 225-230, 2003 | 47 | 2003 |
| The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway Y Luo, H Zhou, L Liu, T Shen, W Chen, B Xu, X Han, F Zhang, RS Scott, ... Oncogene 30 (18), 2098-2107, 2011 | 43 | 2011 |
| Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK H Zhou, C Shang, M Wang, T Shen, L Kong, C Yu, Z Ye, Y Luo, L Liu, Y Li, ... Biochemical pharmacology 116, 39-50, 2016 | 39 | 2016 |
