| Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression BR ,Westley J. Friesen, Yuki Tomizawa, John D. Leszyk, Jin Zhuo, Briana ... PNAS, 2016 | 221* | 2016 |
| Synthetic aminoglycosides efficiently suppress cystic fibrosis transmembrane conductance regulator nonsense mutations and are enhanced by ivacaftor X Xue, V Mutyam, L Tang, S Biswas, M Du, LA Jackson, Y Dai, ... American journal of respiratory cell and molecular biology 50 (4), 805-816, 2014 | 164 | 2014 |
| Discovery of Clinically Approved Agents That Promote Suppression of CFTR Nonsense Mutations VM , Ming Du, Xiaojiao Xue, E Lucile White, J Robert Bostwick, Lynn ... American Journal of Respiratory and Critical Care Medicine, 2016 | 96* | 2016 |
| Identification of the amino acids inserted during suppression of CFTR nonsense mutations and determination of their functional consequences X Xue, V Mutyam, A Thakerar, J Mobley, RJ Bridges, SM Rowe, ... Human molecular genetics 26 (16), 3116-3129, 2017 | 89 | 2017 |
| A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion J Sharma, M Du, E Wong, V Mutyam, Y Li, J Chen, J Wangen, K Thrasher, ... Nature communications 12 (1), 4358, 2021 | 74 | 2021 |
| Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma CM Krane, B Deng, V Mutyam, CA McDonald, S Pazdziorko, L Mason, ... Cytokine 46 (1), 111-118, 2009 | 53 | 2009 |
| Therapeutic benefit observed with the CFTR potentiator, ivacaftor, in a CF patient homozygous for the W1282X CFTR nonsense mutation Venkateshwar Mutyam,Emily Falk Libby, Ning Peng, Denis Hadjiliadis, Michael ... Journal of Cystic Fibrosis, 2016 | 52* | 2016 |
| Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+ 10 kb C-to-T splicing mutation YS Oren, MIT Sinai, A Golec, O Barchad-Avitzur, V Mutyam, Y Li, J Hong, ... Journal of Cystic Fibrosis 20 (5), 865-875, 2021 | 37 | 2021 |
| Dynamic regulation of aquaglyceroporin expression in erythrocyte cultures from cold‐ and warm‐acclimated cope's gray treefrog, Hyla chrysoscelis V Mutyam, MV Puccetti, J Frisbie, DL Goldstein, CM Krane Journal of Experimental Zoology Part A: Ecological Genetics and Physiology …, 2011 | 21 | 2011 |
| Novel correctors and potentiators enhance translational readthrough in CFTR nonsense mutations V Mutyam, J Sharma, Y Li, N Peng, J Chen, LP Tang, E Falk Libby, ... American Journal of Respiratory Cell and Molecular Biology 64 (5), 604-616, 2021 | 16 | 2021 |
| Evaluation of a novel CFTR potentiator in COPD ferrets with acquired CFTR dysfunction N Kaza, VY Lin, D Stanford, SS Hussain, EF Libby, H Kim, M Borgonovi, ... European respiratory journal 60 (1), 2022 | 11 | 2022 |
| J Bridges R, Baasov T, Hong J, Bedwell DM, Rowe SM. Synthetic aminoglycosides efficiently suppress cystic fibrosis transmembrane conductance regulator nonsense mutations and … X Xue, V Mutyam, L Tang, S Biswas, M Du, LA Jackson, Y Dai, ... American Journal of Respiratory Cell and Molecular Biology 50, 805-816, 2014 | 11 | 2014 |
| Ataluren/ivacaftor combination therapy: Two N‐of‐1 trials in cystic fibrosis patients with nonsense mutations JE Peabody Lever, V Mutyam, HY Hathorne, N Peng, J Sharma, ... Pediatric pulmonology 55 (7), 1838-1842, 2020 | 10 | 2020 |
| Synthetic aminoglycosides efficiently suppress CFTR nonsense mutations and are enhanced by ivacaftor X Xue, V Mutyam, L Tang, S Biswas, M Du, LA Jackson, Y Dai, ... Am J Respir Cell Mol Biol 10, 2013 | 8 | 2013 |
| Endo-Porter–mediated delivery of phosphorodiamidate morpholino oligos (PMOs) in erythrocyte suspension cultures from Cope's gray treefrog Hyla chrysoscelis V Mutyam, MV Puccetti, J Frisbie, DL Goldstein, CM Krane Biotechniques 50 (5), 329-332, 2011 | 8 | 2011 |
| WS01. 3 Translational read-through of CFTR nonsense mutations and inducement of cystic fibrosis transmembrane conductance regulator (CFTR) function by ELX-02 treatment SM Rowe, V Mutyam, I Alroy, P Huertas Journal of Cystic Fibrosis 17, S2, 2018 | 4 | 2018 |
| 552: New combination readthrough agents and CFTR corrector therapy to improve CFTR function of cystic fibrosis with nonsense mutation J Chen, V Mutyam, N Peng, Y Li, L Tang, S Rowe Journal of Cystic Fibrosis 20, S261, 2021 | 1 | 2021 |
| EFFECTIVENESS OF MODEL SYSTEMS FOR THERAPEUTIC READTHROUGH DRUG SCREENS M Du, K Liu, L Chen, K Thrasher, KM Keeling, L Rasmussen, B Bostwick, ... Pediatric pulmonology 53, 254-254, 2018 | 1 | 2018 |
| Methods and compounds for stimulating read-through of premature termination codons S Rowe, DM Bedwell, V MUTYAM, DU Ming | 1 | 2017 |
| IDENTIFICATION OF AGENTS THAT SUPPRESS PREMATURE TERMINATION CODONS (PTCS) AND NONSENSE MEDIATED DECAY V Mutyam, M Du, N Peng, J Sharma, R Bostwick, T Smalley, ... Pediatric pulmonology 52, S318-S319, 2017 | 1 | 2017 |
David M. BedwellProfessor & Chair, Dept of Biochemistry & Molecular Genetics, UABVerified email at uab.edu
