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Vinay Sagar
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Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy.
Han H, Jain AD, Truica MI, Izquierdo-Ferrer J, Anker JF, Lysy B, Sagar V ...
Cancer Cell 36, 1–15, 2019
294*2019
Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1
EF Matassa DS, Amoroso MR, Agliarulo I, Maddalena F, Sisinni L, Paladino S ...
Cell Death & Disease 4, 2013
1142013
Nivolumab in metastatic adrenocortical carcinoma: results of a phase 2 trial
BA Carneiro, B Konda, RB Costa, RLB Costa, V Sagar, DB Gursel, ...
The Journal of Clinical Endocrinology & Metabolism 104 (12), 6193-6200, 2019
1092019
Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer
R Vatapalli, V Sagar, Y Rodriguez, JC Zhao, K Unno, S Pamarthy, B Lysy, ...
Nature communications 11 (1), 4153, 2020
772020
Acquired resistance to poly (ADP-ribose) polymerase inhibitor olaparib in BRCA2-associated prostate cancer resulting from biallelic BRCA2 reversion mutations restores both …
BA Carneiro, KA Collier, RJ Nagy, S Pamarthy, V Sagar, S Fairclough, ...
JCO precision oncology 2, 2018
622018
Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D in tumor cells lacking functional p53
A Russo, V Pagliara, F Albano, D Esposito, V Sagar, F Loreni, C Irace, ...
Cell Cycle 15 (1), 41-51, 2016
562016
Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP
D Esposito, E Crescenzi, V Sagar, F Loreni, A Russo, G Russo
Oncotarget 5 (22), 11737, 2014
532014
EphB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells
Vinay Sagar, Rajita Vatapalli, Barbara Lysy, Sahithi Pamarthy, Jonathan F ...
Cell Death & Disease 10 (11), 2019
442019
Anaplastic Lymphoma Kinase Mutation (ALK F1174C) in Small Cell Carcinoma of the Prostate and Molecular Response to Alectinib
BA Carneiro, S Pamarthy, AN Shah, V Sagar, K Unno, HY Han, XJ Yang, ...
Clinical Cancer Research 24 (12), 2732-2739, 2018
362018
Overcoming immunosuppression in bone metastases
ZZ Reinstein, S Pamarthy, V Sagar, R Costa, SA Abdulkadir, FJ Giles, ...
Critical reviews in oncology/hematology 117, 114-127, 2017
362017
TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: Relevance in human colorectal tumors
DS Matassa, I Agliarulo, MR Amoroso, F Maddalena, L Sepe, MC Ferrari, ...
Molecular oncology 8 (8), 1482-1494, 2014
332014
Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A …
A Arivazhagan, DM Kumar, V Sagar, IRP Patric, S Sridevi, B Thota, ...
Journal of neuro-oncology 107, 289-297, 2012
312012
A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression
AG Holmes, JB Parker, V Sagar, MI Truica, PN Soni, H Han, GE Schiltz, ...
Science Advances 8 (17), eabh3635, 2022
282022
Activated ALK cooperates with N-Myc via Wnt/β-catenin signaling to induce neuroendocrine prostate cancer
K Unno, ZR Chalmers, S Pamarthy, R Vatapalli, Y Rodriguez, B Lysy, ...
Cancer research 81 (8), 2157-2170, 2021
282021
PIM1 destabilization activates a p53-dependent response to ribosomal stress in cancer cells.
V Sagar, S Caldarola, V Aria, V Monteleone, C Fuoco, C Gargioli, ...
Oncotarget, 2016
242016
A genome-wide CRISPR activation screen identifies PRRX2 as a regulator of enzalutamide resistance in prostate cancer
Y Rodríguez, K Unno, MI Truica, ZR Chalmers, YA Yoo, R Vatapalli, ...
Cancer research 82 (11), 2110-2123, 2022
112022
Inflammatory bowel disease induces inflammatory and pre-neoplastic changes in the prostate
AS Desai, V Sagar, B Lysy, AB Weiner, OS Ko, C Driscoll, Y Rodriguez, ...
Prostate cancer and prostatic diseases 25 (3), 463-471, 2022
82022
A phase II study of sEphB4-HSA in metastatic castration-resistant prostate cancer
DJ VanderWeele, M Kocherginsky, S Munir, B Martone, V Sagar, ...
Clinical Genitourinary Cancer 20 (6), 575-580, 2022
22022
A phase II study of sEphB4-HSA in metastatic castration-resistant prostate cancer (mCRPC).
MC Burns, V Sagar, B Jovanovic, AK Morgans, DJ VanderWeele, ...
Journal of Clinical Oncology 38 (6_suppl), TPS274-TPS274, 2020
22020
combining anti-androgen therapy and PARP inhibition results in synergistic cytotoxicity of metastatic castration-resistant prostate cancer (mCRPC) cells
S Pamarthy, V Sagar, RJ Vatapalli, Z Reinstein, MZ Ansari, BAC Filho, ...
Cancer Research 77 (13_Supplement), 1114-1114, 2017
12017
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