Therapeutic drug monitoring of tacrolimus-personalized therapy: second consensus report M Brunet, T Van Gelder, A Åsberg, V Haufroid, DA Hesselink, L Langman, ... Therapeutic drug monitoring 41 (3), 261-307, 2019 | 506 | 2019 |
A New Functional CYP3A4 Intron 6 Polymorphism Significantly Affects Tacrolimus Pharmacokinetics in Kidney Transplant Recipients L Elens, R Bouamar, DA Hesselink, V Haufroid, IP van der Heiden, ... Clinical chemistry 57 (11), 1574-1583, 2011 | 290 | 2011 |
The role of pharmacogenetics in the disposition of and response to tacrolimus in solid organ transplantation DA Hesselink, R Bouamar, L Elens, RHN Van Schaik, T Van Gelder Clinical pharmacokinetics 53, 123-139, 2014 | 276 | 2014 |
CYP3A4*22: promising newly identified CYP3A4 variant allele for personalizing pharmacotherapy L Elens, T Van Gelder, DA Hesselink, V Haufroid, RHN Van Schaik Pharmacogenomics 14 (1), 47-62, 2013 | 241 | 2013 |
CYP3A5 and ABCB1 Polymorphisms and Tacrolimus Pharmacokinetics in Renal Transplant Candidates: Guidelines from an Experimental Study V Haufroid, P Wallemacq, V VanKerckhove, L Elens, M De Meyer, ... American journal of transplantation 6 (11), 2706-2713, 2006 | 221 | 2006 |
Effect of a new functional CYP3A4 polymorphism on calcineurin inhibitors’ dose requirements and trough blood levels in stable renal transplant patients L Elens, RH Van Schaik, N Panin, M De Meyer, P Wallemacq, D Lison, ... Pharmacogenomics 12 (10), 1383-1396, 2011 | 200 | 2011 |
CYP3A5 and ABCB1 polymorphisms influence tacrolimus concentrations in peripheral blood mononuclear cells after renal transplantation A Capron, M Mourad, M De Meyer, L De Pauw, DC Eddour, D Latinne, ... Pharmacogenomics 11 (5), 703-714, 2010 | 148 | 2010 |
1199G> A and 2677G> T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation L Elens, A Capron, V Van Kerckhove, J Lerut, M Mourad, D Lison, ... Pharmacogenetics and genomics 17 (10), 873-883, 2007 | 127 | 2007 |
Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study L Elens, ML Becker, V Haufroid, A Hofman, LE Visser, AG Uitterlinden, ... Pharmacogenetics and genomics 21 (12), 861-866, 2011 | 126 | 2011 |
CYP3A4*22 Genotype and Systemic Exposure Affect Paclitaxel-Induced Neurotoxicity AJM de Graan, L Elens, JA Sprowl, A Sparreboom, LE Friberg, ... Clinical Cancer Research 19 (12), 3316-3324, 2013 | 112 | 2013 |
Personalized therapy for mycophenolate: consensus report by the international association of therapeutic drug monitoring and clinical toxicology S Bergan, M Brunet, DA Hesselink, KL Johnson-Davis, PK Kunicki, ... Therapeutic drug monitoring 43 (2), 150-200, 2021 | 108 | 2021 |
Impact of POR* 28 on the pharmacokinetics of tacrolimus and cyclosporine A in renal transplant patients L Elens, DA Hesselink, R Bouamar, K Budde, JW de Fijter, M De Meyer, ... Therapeutic drug monitoring 36 (1), 71-79, 2014 | 108 | 2014 |
Impact of CYP3A4* 22 allele on tacrolimus pharmacokinetics in early period after renal transplantation: toward updated genotype-based dosage guidelines L Elens, A Capron, RHN van Schaik, M De Meyer, L De Pauw, DC Eddour, ... Therapeutic drug monitoring 35 (5), 608-616, 2013 | 107 | 2013 |
The new CYP3A4 intron 6 C> T polymorphism (CYP3A4* 22) is associated with an increased risk of delayed graft function and worse renal function in cyclosporine-treated kidney … L Elens, R Bouamar, DA Hesselink, V Haufroid, T van Gelder, ... Pharmacogenetics and genomics 22 (5), 373-380, 2012 | 103 | 2012 |
Influence of polymorphic OATP1B-type carriers on the disposition of docetaxel AJM de Graan, CS Lancaster, A Obaidat, B Hagenbuch, L Elens, ... Clinical Cancer Research 18 (16), 4433-4440, 2012 | 97 | 2012 |
A New CYP3A5*3 and CYP3A4*22 Cluster Influencing Tacrolimus Target Concentrations: A Population Approach F Andreu, H Colom, L Elens, T van Gelder, RHN van Schaik, ... Clinical pharmacokinetics 56, 963-975, 2017 | 88 | 2017 |
Rivaroxaban plasma levels in patients admitted for bleeding events: insights from a prospective study AL Sennesael, AS Larock, J Douxfils, L Elens, G Stillemans, M Wiesen, ... Thrombosis journal 16, 1-8, 2018 | 79 | 2018 |
Pharmacologic treatment of transplant recipients infected with SARS-CoV-2: considerations regarding therapeutic drug monitoring and drug–drug interactions L Elens, LJ Langman, DA Hesselink, S Bergan, DJAR Moes, M Molinaro, ... Therapeutic drug monitoring 42 (3), 360-368, 2020 | 76 | 2020 |
A population pharmacokinetic model to predict the individual starting dose of tacrolimus in adult renal transplant recipients LM Andrews, DA Hesselink, RHN Van Schaik, T van Gelder, JW De Fijter, ... British journal of clinical pharmacology 85 (3), 601-615, 2019 | 75 | 2019 |
The CYP3A4* 22 C> T single nucleotide polymorphism is associated with reduced midazolam and tacrolimus clearance in stable renal allograft recipients H De Jonge, L Elens, H De Loor, RH Van Schaik, DRJ Kuypers The pharmacogenomics journal 15 (2), 144-152, 2015 | 74 | 2015 |