| Rho GTPases modulate malignant transformation of tumor cells JL Orgaz, C Herraiz, V Sanz-Moreno Small GTPases 5 (4), e983867, 2014 | 195 | 2014 |
| Modes of invasion during tumour dissemination P Pandya, JL Orgaz, V Sanz‐Moreno Molecular oncology 11 (1), 5-27, 2017 | 194 | 2017 |
| Diverse matrix metalloproteinase functions regulate cancer amoeboid migration JL Orgaz, P Pandya, R Dalmeida, P Karagiannis, B Sanchez-Laorden, ... Nature communications 5, 4255, 2014 | 193 | 2014 |
| Regional activation of myosin II in cancer cells drives tumor progression via a secretory cross-talk with the immune microenvironment M Georgouli, C Herraiz, E Crosas-Molist, B Fanshawe, O Maiques, ... Cell 176 (4), 757-774. e23, 2019 | 143 | 2019 |
| Emerging molecular targets in melanoma invasion and metastasis JL Orgaz, V Sanz‐Moreno Pigment cell & melanoma research 26 (1), 39-57, 2013 | 125 | 2013 |
| TGF-β-induced transcription sustains amoeboid melanoma migration and dissemination G Cantelli, JL Orgaz, I Rodriguez-Hernandez, P Karagiannis, O Maiques, ... Current biology 25 (22), 2899-2914, 2015 | 119 | 2015 |
| DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer V Moncho-Amor, II De Caceres, E Bandres, B Martinez-Poveda, JL Orgaz, ... Oncogene 30 (6), 668-678, 2011 | 113 | 2011 |
| Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance JL Orgaz, E Crosas-Molist, A Sadok, A Perdrix-Rosell, O Maiques, ... Cancer Cell 37 (1), 85-103. e9, 2020 | 110 | 2020 |
| Cellular plasticity confers migratory and invasive advantages to a population of glioblastoma-initiating cells that infiltrate peritumoral tissue P Ruiz-Ontañon, JL Orgaz, B Aldaz, A Elosegui-Artola, J Martino, ... Stem cells 31 (6), 1075-1085, 2013 | 110 | 2013 |
| Rho GTPase signaling in cancer progression and dissemination E Crosas-Molist, R Samain, L Kohlhammer, JL Orgaz, SL George, ... Physiological Reviews 102 (1), 455-510, 2022 | 107 | 2022 |
| Actomyosin contractility and collective migration: may the force be with you P Pandya, JL Orgaz, V Sanz-Moreno Current opinion in cell biology 48, 87-96, 2017 | 103 | 2017 |
| Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma JL Orgaz, O Ladhani, KS Hoek, A Fernandez-Barral, D Mihic, O Aguilera, ... Oncogene 28 (47), 4147-4161, 2009 | 90 | 2009 |
| WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion I Rodriguez-Hernandez, O Maiques, L Kohlhammer, G Cantelli, ... Nature communications 11 (1), 5315, 2020 | 71 | 2020 |
| Reactivation of p53 by a cytoskeletal sensor to control the balance between DNA damage and tumor dissemination C Herraiz, F Calvo, P Pandya, G Cantelli, I Rodriguez-Hernandez, ... Journal of the National Cancer Institute 108 (1), djv289, 2016 | 65 | 2016 |
| V600EBRAF promotes invasiveness of thyroid cancer cells by decreasing E-cadherin expression through a Snail-dependent mechanism P Baquero, I Sánchez-Hernández, E Jiménez-Mora, JL Orgaz, B Jiménez, ... Cancer Letters 335 (1), 232-241, 2013 | 61 | 2013 |
| Pigment epithelium-derived factor blocks tumor extravasation by suppressing amoeboid morphology and mesenchymal proteolysis O Ladhani, C Sánchez-Martinez, JL Orgaz, B Jimenez, OV Volpert Neoplasia 13 (7), 633-IN11, 2011 | 56 | 2011 |
| CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion AJ Farrugia, J Rodríguez, JL Orgaz, M Lucas, V Sanz-Moreno, F Calvo Journal of Cell Biology 219 (9), e201912159, 2020 | 48 | 2020 |
| Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer O Aguilera, JM González-Sancho, S Zazo, R Rincon, AF Fernandez, ... Oncotarget 6 (8), 5903, 2015 | 45 | 2015 |
| Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism A Fernández-Barral, JL Orgaz, V Gomez, L Del Peso, MJ Calzada, ... PloS one 7 (3), e32989, 2012 | 42 | 2012 |
| Functional impact of cancer-associated mutations in the tumor suppressor protein ING4 A Moreno, A Palacios, JL Orgaz, B Jimenez, FJ Blanco, I Palmero Carcinogenesis 31 (11), 1932-1938, 2010 | 36 | 2010 |
