Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures A Suzuki, T Yamanaka, T Hirose, N Manabe, K Mizuno, M Shimizu, ... The Journal of cell biology 152 (6), 1183-1196, 2001 | 544 | 2001 |
Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of … A Yamashita, T Ohnishi, I Kashima, Y Taya, S Ohno Genes & development 15 (17), 2215-2228, 2001 | 486 | 2001 |
Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7 T Ohnishi, A Yamashita, I Kashima, T Schell, KR Anders, A Grimson, ... Molecular cell 12 (5), 1187-1200, 2003 | 384 | 2003 |
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay A Yamashita, N Izumi, I Kashima, T Ohnishi, B Saari, Y Katsuhata, ... Genes & development 23 (9), 1091-1105, 2009 | 280 | 2009 |
Fabp7 Maps to a Quantitative Trait Locus for a Schizophrenia Endophenotype A Watanabe, T Toyota, Y Owada, T Hayashi, Y Iwayama, M Matsumata, ... PLoS biology 5 (11), e297, 2007 | 213 | 2007 |
Enhanced carbonyl stress in a subpopulation of schizophrenia M Arai, H Yuzawa, I Nohara, T Ohnishi, N Obata, Y Iwayama, S Haga, ... Archives of general psychiatry 67 (6), 589-597, 2010 | 190 | 2010 |
Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia K Yamada, DJ Gerber, Y Iwayama, T Ohnishi, H Ohba, T Toyota, J Aruga, ... Proceedings of the National Academy of Sciences 104 (8), 2815-2820, 2007 | 182 | 2007 |
Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels K Yamada, T Ohnishi, K Hashimoto, H Ohba, Y Iwayama-Shigeno, ... Biological psychiatry 57 (12), 1493-1503, 2005 | 169 | 2005 |
Genome-wide expression analysis detects eight genes with robust alterations specific to bipolar I disorder: relevance to neuronal network perturbation N Nakatani, E Hattori, T Ohnishi, B Dean, Y Iwayama, I Matsumoto, T Kato, ... Human molecular genetics 15 (12), 1949-1962, 2006 | 160 | 2006 |
Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression K Yamada, E Hattori, Y Iwayama, T Ohnishi, H Ohba, T Toyota, H Takao, ... Biological psychiatry 60 (2), 192-201, 2006 | 110 | 2006 |
Analysis of induced pluripotent stem cells carrying 22q11. 2 deletion M Toyoshima, W Akamatsu, Y Okada, T Ohnishi, S Balan, Y Hisano, ... Translational psychiatry 6 (11), e934-e934, 2016 | 106 | 2016 |
Inhibition of nonsense‐mediated mRNA decay rescues the phenotype in Ullrich's disease F Usuki, A Yamashita, I Higuchi, T Ohnishi, T Shiraishi, M Osame, S Ohno Annals of Neurology: Official Journal of the American Neurological …, 2004 | 104 | 2004 |
Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies C Shimamoto, T Ohnishi, M Maekawa, A Watanabe, H Ohba, R Arai, ... Human molecular genetics 23 (24), 6495-6511, 2014 | 101 | 2014 |
MAPK-upstream protein kinase (MUK) regulates the radial migration of immature neurons in telencephalon of mouse embryo S Hirai, A Kawaguchi, R Hirasawa, M Baba, T Ohnishi, S Ohno Oxford University Press for The Company of Biologists Limited 129 (19), 4483 …, 2002 | 98 | 2002 |
Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1 T Ohnishi, H Ohba, KC Seo, J Im, Y Sato, Y Iwayama, T Furuichi, ... Journal of Biological Chemistry 282 (1), 637-646, 2007 | 93 | 2007 |
Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes M Maekawa, A Watanabe, Y Iwayama, T Kimura, K Hamazaki, S Balan, ... Translational psychiatry 7 (9), e1229-e1229, 2017 | 86 | 2017 |
Genome-wide association study of schizophrenia in Japanese population K Yamada, Y Iwayama, E Hattori, K Iwamoto, T Toyota, T Ohnishi, H Ohba, ... PloS one 6 (6), e20468, 2011 | 85 | 2011 |
Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia M Ide, T Ohnishi, M Murayama, I Matsumoto, K Yamada, Y Iwayama, ... Journal of Neurochemistry 99 (1), 277-287, 2006 | 72 | 2006 |
Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex A Lopez-Perrote, R Castano, R Melero, T Zamarro, H Kurosawa, ... Nucleic acids research 44 (4), 1909-1923, 2016 | 58 | 2016 |
A population-specific uncommon variant in GRIN3A associated with schizophrenia A Takata, Y Iwayama, Y Fukuo, M Ikeda, T Okochi, M Maekawa, T Toyota, ... Biological psychiatry 73 (6), 532-539, 2013 | 55 | 2013 |