| Active and inactive protein kinases: structural basis for regulation LN Johnson, MEM Noble, DJ Owen Cell 85 (2), 149-158, 1996 | 1807 | 1996 |
| Protein kinase inhibitors: insights into drug design from structure MEM Noble, JA Endicott, LN Johnson Science 303 (5665), 1800-1805, 2004 | 1680 | 2004 |
| Presenting your structures: the CCP4mg molecular-graphics software S McNicholas, E Potterton, KS Wilson, MEM Noble Acta Crystallographica Section D: Biological Crystallography 67 (4), 386-394, 2011 | 1369 | 2011 |
| Developments in the CCP4 molecular-graphics project L Potterton, S McNicholas, E Krissinel, J Gruber, K Cowtan, P Emsley, ... Acta Crystallographica Section D: Biological Crystallography 60 (12), 2288-2294, 2004 | 705 | 2004 |
| The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases NR Brown, MEM Noble, JA Endicott, LN Johnson Nature cell biology 1 (7), 438-443, 1999 | 695 | 1999 |
| Crystal structure of a Src-homology 3 (SH3) domain A Musacchio, M Noble, R Pauptit, R Wierenga, M Saraste Nature 359 (6398), 851-855, 1992 | 597 | 1992 |
| The structural basis for control of eukaryotic protein kinases JA Endicott, MEM Noble, LN Johnson Annual review of biochemistry 81 (1), 587-613, 2012 | 495 | 2012 |
| CCP4i2: the new graphical user interface to the CCP4 program suite L Potterton, J Agirre, C Ballard, K Cowtan, E Dodson, PR Evans, ... Acta Crystallographica Section D: Structural Biology 74 (2), 68-84, 2018 | 460 | 2018 |
| Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease A Douangamath, D Fearon, P Gehrtz, T Krojer, P Lukacik, CD Owen, ... Nature communications 11 (1), 5047, 2020 | 449 | 2020 |
| Structures of the Cd44–hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction S Banerji, AJ Wright, M Noble, DJ Mahoney, ID Campbell, AJ Day, ... Nature structural & molecular biology 14 (3), 234-239, 2007 | 430 | 2007 |
| The crystal structure of triacylglycerol lipase from Pseudomonas glumae reveals a partially redundant catalytic aspartate MEM Noble, A Cleasby, LN Johnson, MR Egmond, LGJ Frenken FEBS letters 331 (1-2), 123-128, 1993 | 395 | 1993 |
| A structural explanation for the binding of multiple ligands by the α-adaptin appendage domain DJ Owen, Y Vallis, MEM Noble, JB Hunter, TR Dafforn, PR Evans, ... Cell 97 (6), 805-815, 1999 | 349 | 1999 |
| Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2 AM Lawrie, ME Noble, P Tunnah, NR Brown, LN Johnson, JA Endicott Nature structural biology 4 (10), 796-801, 1997 | 334 | 1997 |
| Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44 P Teriete, S Banerji, M Noble, CD Blundell, AJ Wright, AR Pickford, ... Molecular cell 13 (4), 483-496, 2004 | 300 | 2004 |
| Crystal structure of the SH3 domain in human Fyn; comparison of the three‐dimensional structures of SH3 domains in tyrosine kinases and spectrin. ME Noble, A Musacchio, M Saraste, SA Courtneidge, RK Wierenga The EMBO journal 12 (7), 2617-2624, 1993 | 296 | 1993 |
| Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3 N Macdonald, JPI Welburn, MEM Noble, A Nguyen, MB Yaffe, D Clynes, ... Molecular cell 20 (2), 199-211, 2005 | 291 | 2005 |
| Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor TG Davies, J Bentley, CE Arris, FT Boyle, NJ Curtin, JA Endicott, ... Nature structural biology 9 (10), 745-749, 2002 | 282 | 2002 |
| The structural basis for substrate recognition and control by protein kinases LN Johnson, ED Lowe, MEM Noble, DJ Owen FEBS letters 430 (1-2), 1-11, 1998 | 282 | 1998 |
| Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity NR Brown, MEM Noble, AM Lawrie, MC Morris, P Tunnah, G Divita, ... Journal of Biological Chemistry 274 (13), 8746-8756, 1999 | 274 | 1999 |
| The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition ED Lowe, MEM Noble, VT Skamnaki, NG Oikonomakos, DJ Owen, ... The EMBO journal, 1997 | 274 | 1997 |
Jane EndicottProfessor of Cancer Structural Biology, Newcastle UniversityVerified email at ncl.ac.uk
