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Gregory M. K. Poon
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Year
Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells
GMK Poon, J Gariepy
Biochemical Society Transactions 35 (4), 788-793, 2007
2862007
PU. 1 controls fibroblast polarization and tissue fibrosis
T Wohlfahrt, S Rauber, S Uebe, M Luber, A Soare, A Ekici, S Weber, ...
Nature 566 (7744), 344-349, 2019
1482019
ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma
P Mao, AJ Brown, S Esaki, S Lockwood, GMK Poon, MJ Smerdon, ...
Nature communications 9 (1), 2626, 2018
1322018
Prodrug applications for targeted cancer therapy
I Giang, EL Boland, GMK Poon
The AAPS journal 16, 899-913, 2014
1192014
Pharmacological inhibition of the transcription factor PU. 1 in leukemia
I Antony-Debré, A Paul, J Leite, K Mitchell, HM Kim, LA Carvajal, ...
The Journal of clinical investigation 127 (12), 4297-4313, 2017
1072017
The catalytic subunit of Shiga-like toxin 1 interacts with ribosomal stalk proteins and is inhibited by their conserved C-terminal domain
AJ McCluskey, GMK Poon, E Bolewska-Pedyczak, T Srikumar, SM Jeram, ...
Journal of molecular biology 378 (2), 375-386, 2008
922008
DNA mismatches reveal conformational penalties in protein–DNA recognition
A Afek, H Shi, A Rangadurai, H Sahay, A Senitzki, S Xhani, M Fang, ...
Nature 587 (7833), 291-296, 2020
852020
The importance of valency in enhancing the import and cell routing potential of protein transduction domain-containing molecules
M Sung, GMK Poon, J Gariépy
Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (3), 355-363, 2006
792006
Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines
M Munde, S Wang, A Kumar, CE Stephens, AA Farahat, DW Boykin, ...
Nucleic acids research, gkt955, 2013
762013
Base coupling in sequence-specific site recognition by the ETS domain of murine PU. 1
GMK Poon, RB Macgregor Jr
Journal of molecular biology 328 (4), 805-819, 2003
422003
Quantitative investigation of protein–nucleic acid interactions by biosensor surface Plasmon resonance
S Wang, GMK Poon, WD Wilson
DNA-Protein Interactions: Principles and Protocols, 313-332, 2015
412015
Explicit formulation of titration models for isothermal titration calorimetry
GMK Poon
Analytical biochemistry 400 (2), 229-236, 2010
412010
Mechanistic Heterogeneity in Site Recognition by the Structurally Homologous DNA-Binding Domains of the ETS-Family Transcription Factors Ets-1 and PU.1
S Wang, MH Linde, M Munde, VD Carvalho, WD Wilson, GMK Poon
Journal of Biological Chemistry, jbc. M114. 575340, 2014
382014
Pharmacologic efficacy of PU. 1 inhibition by heterocyclic dications: a mechanistic analysis
DC Stephens, HM Kim, A Kumar, AA Farahat, DW Boykin, GM Poon
Nucleic acids research 44 (9), 4005-4013, 2016
362016
A rapid and universal tandem‐purification strategy for recombinant proteins
AJ McCluskey, GMK Poon, J Gariépy
Protein Science 16 (12), 2726-2732, 2007
362007
Constrained chromatin accessibility in PU. 1-mutated agammaglobulinemia patients
C Le Coz, DN Nguyen, C Su, BE Nolan, AV Albrecht, S Xhani, D Sun, ...
Journal of Experimental Medicine 218 (7), e20201750, 2021
352021
Sequence discrimination by DNA-binding domain of ETS family transcription factor PU. 1 is linked to specific hydration of protein-DNA interface
GMK Poon
Journal of Biological Chemistry 287 (22), 18297-18307, 2012
352012
Differential sensitivity to methylated DNA by ETS-family transcription factors is intrinsically encoded in their DNA-binding domains
DC Stephens, GMK Poon
Nucleic acids research 44 (18), 8671-8681, 2016
342016
Probing the electrostatics and pharmacological modulation of sequence-specific binding by the DNA-binding domain of the ETS family transcription factor PU. 1: a binding …
M Munde, GMK Poon, WD Wilson
Journal of molecular biology 425 (10), 1655-1669, 2013
342013
Tandem dimerization of the human p53 tetramerization domain stabilizes a primary dimer intermediate and dramatically enhances its oligomeric stability
GMK Poon, RD Brokx, M Sung, J Gariépy
Journal of molecular biology 365 (4), 1217-1231, 2007
342007
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