| Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death LA Volpicelli-Daley, KC Luk, TP Patel, SA Tanik, DM Riddle, A Stieber, ... Neuron 72 (1), 57-71, 2011 | 1616 | 2011 |
| Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates LA Volpicelli-Daley, KC Luk, VMY Lee Nature protocols 9 (9), 2135-2146, 2014 | 619 | 2014 |
| Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease O Cooper, H Seo, S Andrabi, C Guardia-Laguarta, J Graziotto, ... Science translational medicine 4 (141), 141ra90-141ra90, 2012 | 557 | 2012 |
| Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice W Zhang, AS Basile, J Gomeza, LA Volpicelli, AI Levey, J Wess Journal of Neuroscience 22 (5), 1709-1717, 2002 | 376 | 2002 |
| Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy*♦ SA Tanik, CE Schultheiss, LA Volpicelli-Daley, KR Brunden, VMY Lee Journal of Biological Chemistry 288 (21), 15194-15210, 2013 | 358 | 2013 |
| Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus LA Volpicelli, AI Levey Progress in brain research 145, 59-66, 2004 | 339 | 2004 |
| Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice C Challis, A Hori, TR Sampson, BB Yoo, RC Challis, AM Hamilton, ... Nature Neuroscience 23 (3), 327-336, 2020 | 295 | 2020 |
| Isoform-selective effects of the depletion of ADP-ribosylation factors 1–5 on membrane traffic LA Volpicelli-Daley, Y Li, CJ Zhang, RA Kahn Molecular biology of the cell 16 (10), 4495-4508, 2005 | 278 | 2005 |
| Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes LA Volpicelli-Daley, KL Gamble, CE Schultheiss, DM Riddle, AB West, ... Molecular biology of the cell 25 (25), 4010-4023, 2014 | 257 | 2014 |
| microRNA-155 regulates alpha-synuclein-induced inflammatory responses in models of Parkinson disease AD Thome, AS Harms, LA Volpicelli-Daley, DG Standaert Journal of Neuroscience 36 (8), 2383-2390, 2016 | 253 | 2016 |
| Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient rats JPL Daher, LA Volpicelli-Daley, JP Blackburn, MS Moehle, AB West Proceedings of the National Academy of Sciences 111 (25), 9289-9294, 2014 | 235 | 2014 |
| Calcium entry and α-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons DI Dryanovski, JN Guzman, Z Xie, DJ Galteri, LA Volpicelli-Daley, ... Journal of Neuroscience 33 (24), 10154-10164, 2013 | 231 | 2013 |
| Best practices for generating and using alpha-synuclein pre-formed fibrils to model Parkinson’s disease in rodents NK Polinski, LA Volpicelli-Daley, CE Sortwell, KC Luk, N Cremades, ... Journal of Parkinson's disease 8 (2), 303-322, 2018 | 228 | 2018 |
| TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways AS Chen-Plotkin, TL Unger, MD Gallagher, E Bill, LK Kwong, ... Journal of Neuroscience 32 (33), 11213-11227, 2012 | 228 | 2012 |
| Wnt3a-mediated formation of phosphatidylinositol 4, 5-bisphosphate regulates LRP6 phosphorylation W Pan, SC Choi, H Wang, Y Qin, L Volpicelli-Daley, L Swan, L Lucast, ... Science 321 (5894), 1350-1353, 2008 | 213 | 2008 |
| Leucine-rich repeat kinase 2 (LRRK2) pharmacological inhibition abates α-synuclein gene-induced neurodegeneration JPL Daher, HA Abdelmotilib, X Hu, LA Volpicelli-Daley, MS Moehle, ... Journal of Biological Chemistry 290 (32), 19433-19444, 2015 | 212 | 2015 |
| Initiation and propagation of α-synuclein aggregation in the nervous system BA Hijaz, LA Volpicelli-Daley Molecular neurodegeneration 15, 1-12, 2020 | 208 | 2020 |
| Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease D Grassi, S Howard, M Zhou, N Diaz-Perez, NT Urban, D Guerrero-Given, ... Proceedings of the National Academy of Sciences 115 (11), E2634-E2643, 2018 | 204 | 2018 |
| G2019S-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons LA Volpicelli-Daley, H Abdelmotilib, Z Liu, L Stoyka, JPL Daher, ... Journal of Neuroscience 36 (28), 7415-7427, 2016 | 194 | 2016 |
| LRRK2 antisense oligonucleotides ameliorate α-synuclein inclusion formation in a Parkinson’s disease mouse model HT Zhao, N John, V Delic, K Ikeda-Lee, A Kim, A Weihofen, EE Swayze, ... Molecular Therapy-Nucleic Acids 8, 508-519, 2017 | 189 | 2017 |
