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Paulo Paixão
Paulo Paixão
iMED.pt; Faculdade de Farmácia; University of Lisbon; INFARMED; ULHT;
Email confirmado em ulusofona.pt - Página inicial
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Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs
B Hens, Y Tsume, M Bermejo, P Paixao, MJ Koenigsknecht, JR Baker, ...
Molecular pharmaceutics 14 (12), 4281-4294, 2017
1192017
Metabolism of primaquine by liver homogenate fractions: Evidence for monoamine oxidase and cytochrome P450 involvement in the oxidative deamination of primaquine to …
L Constantino, P Paixao, R Moreira, MJ Portela, VE Do Rosario, J Iley
Experimental and Toxicologic Pathology 51 (4), 299-303, 1999
941999
Simple method for determination of paraquat in plasma and serum of human patients by high-performance liquid chromatography
P Paixao, P Costa, T Bugalho, C Fidalgo, LM Pereira
Journal of Chromatography B 775 (1), 109-113, 2002
802002
Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model
P Paixão, LF Gouveia, JAG Morais
International Journal of Pharmaceutics 429 (1-2), 84-98, 2012
742012
Prediction of the in vitro permeability determined in Caco-2 cells by using artificial neural networks
P Paixão, LF Gouveia, JAG Morais
European Journal of Pharmaceutical Sciences 41 (1), 107-117, 2010
702010
Prediction of the in vitro intrinsic clearance determined in suspensions of human hepatocytes by using artificial neural networks
P Paixão, LF Gouveia, JAG Morais
European Journal of Pharmaceutical Sciences 39 (5), 310-321, 2010
612010
Prediction of drug distribution within blood
P Paixão, LF Gouveia, JAG Morais
european journal of pharmaceutical sciences 36 (4), 544-554, 2009
552009
Evaluation of dissolution profile similarity–Comparison between the f 2, the multivariate statistical distance and the f 2 bootstrapping methods
P Paixão, LF Gouveia, N Silva, JAG Morais
European Journal of Pharmaceutics and Biopharmaceutics 112, 67-74, 2017
462017
Implementing the Biopharmaceutics Classification System in Drug Development: Reconciling Similarities, Differences, and Shared Challenges in the EMA and US-FDA-Recommended …
DB Cardot JM, Garcia Arieta A, Paixao P, Tasevska I
AAPS J 18 (4), 1039-46, 2016
332016
Prediction of Drug Distribution in Rat and Humans Using an Artificial Neural Networks Ensemble and a PBPK Model
P Paixão, N Aniceto, LF Gouveia, JAG Morais
Pharmaceutical research 31 (12), 3313-3322, 2014
162014
Implementing the additional strength biowaiver for generics: EMA recommended approaches and challenges for a US-FDA submission
JM Cardot, AG Arieta, P Paixao, I Tasevska, B Davit
European Journal of Pharmaceutical Sciences, 2017
102017
Population Approach to Efavirenz Therapy
H Duarte, JP Cruz, N Aniceto, AC Ribeiro, A Fernandes, P Paixão, ...
Journal of pharmaceutical sciences 106 (10), 3161-3166, 2017
92017
Tissue-to-blood distribution coefficients in the rat: Utility for estimation of the volume of distribution in man
P Paixão, N Aniceto, LF Gouveia, JAG Morais
European Journal of Pharmaceutical Sciences 50 (3-4), 526-543, 2013
92013
An alternative single dose parameter to avoid the need for steady-state studies on oral extended-release drug products
P Paixão, LF Gouveia, JA Guimarães Morais
European Journal of Pharmaceutics and Biopharmaceutics 80 (2), 410-417, 2011
92011
In silico prediction of human oral bioavailability: artificial neural networks and physiologically based models
P Paixão
Lisbon University, 2010
22010
Linking Gastrointestinal In Vivo Dissolution and Ibuprofen Systemic Absorption
M Bermejo, Y Tsume, P Paixão, B Hens, R Baker, M Koenigsknecht, ...
2017
Dynamic Change in pH by Low Buffer Capacity of Gastrointestinal Fluids Along The Human Gastrointestinal Tract: Implications For In Vivo Dissolution and Absorption of Ionizable …
B Hens, Y Tsume, M Bermejo, P Paixão, M Koenigsknecht, R Baker, ...
2017
Connecting Gastrointestinal In Vivo Dissolution and Systemic Absorption of Oral Ibuprofen Administered After a Meal
P Paixão, M Bermejo, Y Tsume, M Koenigsknecht, B Hens, R Baker, ...
2017
European Journal of Pharmaceutics and Biopharmaceutics Evaluation of dissolution profile similarity–Comparison between the f 2, the multivariate statistical distance and the f …
P Paixão, LF Gouveia, N Silva, JAG Morais
2017
Pharmacokinetics of vancomycin in intensive-care patients
PP Jurij Zdovc, Carla Ferreira Santos, Nuno Silva, José Augusto Guimarães Morais
PAGE meeting Lisbon, 2016
2016
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