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Nicholas DeBouver
Nicholas DeBouver
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Year
Design of protein-binding proteins from the target structure alone
L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ...
Nature 605 (7910), 551-560, 2022
2212022
Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus
MJ Hoy, E Park, H Lee, WY Lim, DC Cole, ND DeBouver, BG Bobay, ...
MBio 13 (3), e01049-22, 2022
102022
Structural characterization of the reaction and substrate specificity mechanisms of pathogenic fungal acetyl-CoA synthetases
AJ Jezewski, KM Alden, TE Esan, ND DeBouver, J Abendroth, JC Bullen, ...
ACS chemical biology 16 (8), 1587-1599, 2021
52021
Crystal Growth in Microgravity for Neutron Diffraction Studies
TC Mueser, C Schall, N Debouver, E Ogbuoji, VN Drago
Acta Cryst 74, a293, 2018
12018
Bacterial structural genomics target enabled by a recently discovered potent fungal acetyl-CoA synthetase inhibitor
ND DeBouver, MJ Bolejack, TE Esan, DJ Krysan, TJ Hagen, J Abendroth
Acta Crystallographica Section F: Structural Biology Communications 79 (6), 2023
2023
Structural Characterization and Mechanistic Insights into Pathogenic Fungal Acetyl-CoA Synthetases
D Fox, N DeBouver, A Jezewski, K Alden, T Esan, J Abendroth, J Bullen, ...
Acta Crystallographica Section A: Foundations and Advances 78, a278-a278, 2022
2022
Protein-Binding Proteins Designed from Target Structural Information
N DeBouver, L Cao, B Coventry, A Bera, W Yang, S Bernard, L Stewart, ...
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 78, A281-A281, 2022
2022
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