| Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system T Sinkunas, G Gasiunas, C Fremaux, R Barrangou, P Horvath, V Siksnys The EMBO journal 30 (7), 1335-1342, 2011 | 589 | 2011 |
| Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes MD Szczelkun, MS Tikhomirova, T Sinkunas, G Gasiunas, T Karvelis, ... Proceedings of the National Academy of Sciences 111 (27), 9798-9803, 2014 | 513 | 2014 |
| In vitro reconstitution of Cascade‐mediated CRISPR immunity in Streptococcus thermophilus T Sinkunas, G Gasiunas, SP Waghmare, MJ Dickman, R Barrangou, ... The EMBO journal 32 (3), 385-394, 2013 | 321 | 2013 |
| Directional R-loop formation by the CRISPR-Cas surveillance complex cascade provides efficient off-target site rejection M Rutkauskas, T Sinkunas, I Songailiene, MS Tikhomirova, V Siksnys, ... Cell reports 10 (9), 1534-1543, 2015 | 180 | 2015 |
| Molecular mechanisms of CRISPR-mediated microbial immunity G Gasiunas, T Sinkunas, V Siksnys Cellular and molecular life sciences 71, 449-465, 2014 | 158 | 2014 |
| BREX system of Escherichia coli distinguishes self from non-self by methylation of a specific DNA site J Gordeeva, N Morozova, N Sierro, A Isaev, T Sinkunas, K Tsvetkova, ... Nucleic acids research 47 (1), 253-265, 2019 | 100 | 2019 |
| DnaQ exonuclease‐like domain of Cas2 promotes spacer integration in a type I‐E CRISPR‐Cas system G Drabavicius, T Sinkunas, A Silanskas, G Gasiunas, Č Venclovas, ... EMBO reports 19 (7), e45543, 2018 | 34 | 2018 |
| DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system D Tuminauskaite, D Norkunaite, M Fiodorovaite, S Tumas, I Songailiene, ... BMC biology 18, 1-16, 2020 | 18 | 2020 |
| Decision-making in Cascade complexes harboring crRNAs of altered length I Songailiene, M Rutkauskas, T Sinkunas, E Manakova, S Wittig, ... Cell reports 28 (12), 3157-3166. e4, 2019 | 13 | 2019 |
| A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complex M Rutkauskas, I Songailiene, P Irmisch, FE Kemmerich, T Sinkunas, ... Nature communications 13 (1), 7460, 2022 | 9 | 2022 |
| Cas3 Nuclease–Helicase Activity Assays T Sinkunas, G Gasiunas, V Siksnys CRISPR: Methods and Protocols, 277-291, 2015 | 9 | 2015 |
| The energy landscape for R-loop formation by the CRISPR–Cas Cascade complex DJ Kauert, J Madariaga-Marcos, M Rutkauskas, A Wulfken, I Songailiene, ... Nature structural & molecular biology 30 (7), 1040-1047, 2023 | 6 | 2023 |
| Dynamic interplay between target search and recognition for a Type I CRISPR-Cas system P Aldag, M Rutkauskas, J Madariaga-Marcos, I Songailiene, T Sinkunas, ... Nature communications 14 (1), 3654, 2023 | 4 | 2023 |
| Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing G Bigelyte, B Duchovska, R Zedaveinyte, G Sasnauskas, T Sinkunas, ... Nucleic Acids Research, gkae016, 2024 | 2 | 2024 |
| Dynamic interplay between target search and recognition for the Cascade surveillance complex of type IE CRISPR-Cas systems P Aldag, M Rutkauskas, J Madariaga-Marcos, I Songailiene, T Sinkunas, ... bioRxiv, 2022.12. 18.520913, 2022 | 2 | 2022 |
| Disarming of type IF CRISPR-Cas surveillance complex by anti-CRISPR proteins AcrIF6 and AcrIF9 E Kupcinskaite, M Tutkus, A Kopūstas, S Ašmontas, M Jankunec, ... Scientific reports 12 (1), 15548, 2022 | 1 | 2022 |
| Energy landscapes of CRISPR/Cas R-loop formation from ultrafast twist measurements JM Marcos, DJ Kauert, M Rutkauskas, A Wulfken, I Songaliene, ... Biophysical Journal 121 (3), 283a, 2022 | | 2022 |
| Dissecting the Target Recognition by CRISPR/Cas Effector Complexes with Ultrafast Twist Measurements JM Marcos, DJ Kauert, M Rutkauskas, A Wulfken, I Songaliene, ... Biophysical Journal 120 (3), 93a-94a, 2021 | | 2021 |
| Investigating and Modelling the Target Recognition Dynamics of the CRISPR-Cas Surveillance Complex Cascade M Rutkauskas, T Sinkūnas, I Songailiene, V Siksnys, R Seidel Biophysical Journal 114 (3), 194a, 2018 | | 2018 |
| Target recognition by Cascade complexes bearing altered length crRNA I Songailiene, M Rutkauskas, T Sinkunas, S Zurhorst, C Schmidt, R Seidel, ... FEBS JOURNAL 284, 167-167, 2017 | | 2017 |
