| Biosynthesis, structure, and folding of the insulin precursor protein M Liu, MA Weiss, A Arunagiri, J Yong, N Rege, J Sun, L Haataja, ... Diabetes, Obesity and Metabolism 20 (S2), 28-50, 2018 | 197 | 2018 |
| Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis J Tian, J Yong, H Dang, DL Kaufman Autoimmunity 44 (6), 465-470, 2011 | 132 | 2011 |
| Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus J Yong, JD Johnson, P Arvan, J Han, RJ Kaufman Nature Reviews Endocrinology 17, 455 - 467, 2021 | 130 | 2021 |
| C/EBP homologous protein-induced macrophage apoptosis protects mice from steatohepatitis H Malhi, EM Kropp, VF Clavo, CR Kobrossi, JS Han, AS Mauer, J Yong, ... Journal of Biological Chemistry 288 (26), 18624-18642, 2013 | 87 | 2013 |
| PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity I Jang, A Pottekat, J Poothong, J Yong, J Lagunas-Acosta, A Charbono, ... Elife 8, e44528, 2019 | 77 | 2019 |
| BCG vaccine-induced neuroprotection in a mouse model of Parkinson's disease J Yong, G Lacan, H Dang, T Hsieh, B Middleton, C Wasserfall, J Tian, ... PLoS One 6 (1), e16610, 2011 | 75 | 2011 |
| Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2+ J Yong, H Bischof, S Burgstaller, M Siirin, A Murphy, R Malli, RJ Kaufman eLife 8, e49682, 2019 | 66 | 2019 |
| C/EBP-Homologous Protein (CHOP) in Vascular Smooth Muscle Cells Regulates Their Proliferation in Aortic Explants and Atherosclerotic Lesions IT Alex-Xianghua Zhou, Xiaobo Wang, Chyuan S Lin, Jaeseok Han, Jing Yong ... Circulation Research, 2015 | 59 | 2015 |
| Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum J Poothong, A Pottekat, M Siirin, AR Campos, AW Paton, JC Paton, ... Blood 135 (21), 1899-1911, 2020 | 49 | 2020 |
| Multimodality imaging of β-cells in mouse models of type 1 and 2 diabetes J Yong, J Rasooly, H Dang, Y Lu, B Middleton, Z Zhang, L Hon, ... Diabetes 60 (5), 1383-1392, 2011 | 42 | 2011 |
| Chop/Ddit3 depletion in β-cells alleviates ER stress and corrects hepatic steatosis in mice J Yong, VS Parekh, SM Reilly, J Nayak, Z Chen, C Lebeaupin, I Jang, ... Science Translational Medicine 13 (604), 2021 | 40 | 2021 |
| Transgenic mice with enhanced neuronal major histocompatibility complex class I expression recover locomotor function better after spinal cord injury MS Joseph, T Bilousova, S Zdunowski, ZP Wu, B Middleton, ... Journal of neuroscience research 89 (3), 365-372, 2011 | 29 | 2011 |
| The Impact of the ER Unfolded Protein Response on Cancer Initiation and Progression: Therapeutic Implications C Lebeaupin, J Yong, R Kaufman Advances in Experimental Medicine and Biology 1243, doi.org/10.1007/978-3 …, 2020 | 18 | 2020 |
| When Less Is Better: ER Stress and Beta Cell Proliferation J Yong, P Itkin-Ansari, RJ Kaufman Developmental Cell 36 (1), 4-6, 2016 | 18 | 2016 |
| Ectopic FVIII expression and misfolding in hepatocytes as a cause for hepatocellular carcinoma A Kapelanski-Lamoureux, Z Chen, ZH Gao, R Deng, A Lazaris, ... Molecular Therapy 30 (12), 3542-3551, 2022 | 11 | 2022 |
| Eukaryotic translation initiation factor 2 α phosphorylation as a therapeutic target in diabetes J Yong, N Grankvist, J Han, RJ Kaufman Expert Review of Endocrinology & Metabolism 9 (4), 345-356, 2014 | 5 | 2014 |
| Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings SM Mastracci TL, Yong J, Pandol SJ Diabetes 72 (4), 433-448, 2023 | 3 | 2023 |
| Integrated physiology of the exocrine and endocrine compartments in pancreatic diseases: Workshop proceedings TL Mastracci, M Apte, LT Amundadottir, A Alvarsson, S Artandi, MD Bellin, ... Pancreas 51 (9), 1061-1073, 2022 | 3 | 2022 |
| Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene J Yong, J Tian, H Dang, TT Wu, MA Atkinson, R Sun, DL Kaufman Scientific reports 9 (1), 4269, 2019 | 2 | 2019 |
| Methods and compositions for treating pancreatic cancer RJ Kaufman, J YONG, S Pandol WO Patent WO2,024,006,782, 2024 | | 2024 |
Randal J. KaufmanProfessor and Director, Degenerative Diseases ProgramVerified email at sbpdiscovery.org
