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Ooi Wen Fong
Ooi Wen Fong
Senior Bioinformatics Specialist, Genome Institute of Singapore
Verified email at gis.a-star.edu.sg
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Cited by
Cited by
Year
Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei
N Chantratita, DA Rholl, B Sim, V Wuthiekanun, D Limmathurotsakul, ...
Proceedings of the National Academy of Sciences 108 (41), 17165-17170, 2011
1722011
Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers
YA Guo, MM Chang, W Huang, WF Ooi, M Xing, P Tan, AJ Skanderup
Nature communications 9 (1), 1520, 2018
1482018
VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma
X Yao, J Tan, KJ Lim, J Koh, WF Ooi, Z Li, D Huang, M Xing, YS Chan, ...
Cancer discovery 7 (11), 1284-1305, 2017
1312017
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity
WF Ooi, M Xing, C Xu, X Yao, MK Ramlee, MC Lim, F Cao, K Lim, D Babu, ...
Nature communications 7 (1), 12983, 2016
1292016
A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A
A Cruz-Migoni, GM Hautbergue, PJ Artymiuk, PJ Baker, M Bokori-Brown, ...
Science 334 (6057), 821-824, 2011
1282011
The Condition-Dependent Transcriptional Landscape of Burkholderia pseudomallei
WF Ooi, C Ong, T Nandi, JF Kreisberg, HH Chua, G Sun, Y Chen, ...
PLoS genetics 9 (9), e1003795, 2013
902013
Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates
BMQ Sim, N Chantratita, WF Ooi, T Nandi, R Tewhey, V Wuthiekanun, ...
Genome biology 11, 1-17, 2010
902010
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements
M Muratani, N Deng, WF Ooi, SJ Lin, M Xing, C Xu, A Qamra, ST Tay, ...
Nature communications 5 (1), 4361, 2014
822014
Epigenomic promoter alterations amplify gene isoform and immunogenic diversity in gastric adenocarcinoma
A Qamra, M Xing, N Padmanabhan, JJT Kwok, S Zhang, C Xu, YS Leong, ...
Cancer discovery 7 (6), 630-651, 2017
502017
HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
TD Yan, WF Ooi, A Qamra, A Cheung, DL Ma, GM Sundaram, C Xu, ...
Nature communications 9 (1), 100, 2018
482018
Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma
WF Ooi, AM Nargund, KJ Lim, S Zhang, M Xing, A Mandoli, JQ Lim, ...
Gut 69 (6), 1039-1052, 2020
462020
HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer
C Xu, WF Ooi, A Qamra, J Tan, BYJ Chua, SWT Ho, K Das, ZFA Isa, Z Li, ...
Gut 69 (2), 231-242, 2020
332020
Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high‐risk neuroblastoma
WF Ooi, A Re, V Sidarovich, V Canella, N Arseni, V Adami, ...
Genes, Chromosomes and Cancer 51 (6), 545-556, 2012
202012
Evolutionary analysis of Burkholderia pseudomallei identifies putative novel virulence genes, including a microbial regulator of host cell autophagy
AP Singh, S Lai, T Nandi, HH Chua, WF Ooi, C Ong, JD Boyce, B Adler, ...
Journal of bacteriology 195 (24), 5487-5498, 2013
192013
Transcriptional profiles of Burkholderia pseudomallei reveal the direct and indirect roles of Sigma E under oxidative stress conditions
S Jitprasutwit, C Ong, N Juntawieng, WF Ooi, CM Hemsley, ...
BMC genomics 15, 1-11, 2014
162014
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer
M Xing, WF Ooi, J Tan, A Qamra, PH Lee, Z Li, C Xu, N Padmanabhan, ...
The Journal of clinical investigation 130 (6), 3005-3020, 2020
152020
Epigenomic promoter alterations amplify gene isoform and immunogenic diversity in gastric adenocarcinoma. Cancer Discov. 2017; 7: 630–651. doi: 10.1158/2159-8290
A Qamra, M Xing, N Padmanabhan, JJT Kwok, S Zhang, C Xu, YS Leong, ...
CD-16-1022.[Abstract][CrossRef][Google Scholar], 0
15
VHL deficiency drives enhancer activation of oncogenes in clear cell renal cell carcinoma. Cancer Discov. 2017; 7: 1284–1305. doi: 10.1158/2159-8290
X Yao, J Tan, KJ Lim, J Koh, WF Ooi, Z Li, D Huang, M Xing, YS Chan, ...
CD-17-0375.[Abstract][CrossRef][Google Scholar], 0
14
Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities
SWT Ho, T Sheng, M Xing, WF Ooi, C Xu, R Sundar, KK Huang, Z Li, ...
Gut 72 (2), 226-241, 2023
132023
Chromatin rewiring by mismatch repair protein MSH2 alters cell adhesion pathways and sensitivity to BET inhibition in gastric cancer
AM Nargund, C Xu, A Mandoli, A Okabe, GB Chen, KK Huang, T Sheng, ...
Cancer Research 82 (14), 2538-2551, 2022
82022
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