| The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs YI Zhu, T Tchkonia, T Pirtskhalava, AC Gower, H Ding, N Giorgadze, ... Aging cell 14 (4), 644-658, 2015 | 1991 | 2015 |
| Selective killing of cancer cells by a small molecule targeting the stress response to ROS L Raj, T Ide, AU Gurkar, M Foley, M Schenone, X Li, NJ Tolliday, ... Nature 475 (7355), 231-234, 2011 | 1163 | 2011 |
| Nuclear genomic instability and aging LJ Niedernhofer, AU Gurkar, Y Wang, J Vijg, JHJ Hoeijmakers, ... Annual review of biochemistry 87, 295-322, 2018 | 227 | 2018 |
| Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice MJ Yousefzadeh, J Zhao, C Bukata, EA Wade, SJ McGowan, LA Angelini, ... Aging cell 19 (3), e13094, 2020 | 202 | 2020 |
| Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress AU Gurkar, K Chu, L Raj, R Bouley, SH Lee, YB Kim, SE Dunn, ... Nature communications 4 (1), 1-13, 2013 | 176 | 2013 |
| Interstrain transfer of the large pathogenicity island (PAPI-1) of Pseudomonas aeruginosa X Qiu, AU Gurkar, S Lory Proceedings of the National Academy of Sciences 103 (52), 19830-19835, 2006 | 171 | 2006 |
| Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging AR Robinson, MJ Yousefzadeh, TA Rozgaja, J Wang, X Li, JS Tilstra, ... Redox biology 17, 259-273, 2018 | 112 | 2018 |
| Small-molecule reactivation of mutant p53 to wild-type-like p53 through the p53-Hsp40 regulatory axis M Hiraki, SY Hwang, S Cao, TR Ramadhar, S Byun, KW Yoon, JH Lee, ... Chemistry & biology 22 (9), 1206-1216, 2015 | 79 | 2015 |
| Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway IY Song, K Palle, A Gurkar, S Tateishi, GM Kupfer, C Vaziri Journal of biological chemistry 285 (41), 31525-31536, 2010 | 74 | 2010 |
| ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging J Zhao, L Zhang, A Lu, Y Han, D Colangelo, C Bukata, A Scibetta, ... Aging (Albany NY) 12 (6), 4688, 2020 | 70 | 2020 |
| Cellular senescence: the trojan horse in chronic lung diseases S Hamsanathan, JK Alder, J Sellares, M Rojas, AU Gurkar, AL Mora American journal of respiratory cell and molecular biology 61 (1), 21-30, 2019 | 56 | 2019 |
| Comparison of mice with accelerated aging caused by distinct mechanisms AU Gurkar, LJ Niedernhofer Experimental gerontology 68, 43-50, 2015 | 56 | 2015 |
| Lipids as regulators of cellular senescence S Hamsanathan, AU Gurkar Frontiers in physiology 13, 796850, 2022 | 50 | 2022 |
| c-Jun N-terminal kinase–mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks LR Barkley, K Palle, M Durando, TA Day, A Gurkar, N Kakusho, J Li, ... Molecular biology of the cell 23 (10), 1943-1954, 2012 | 43 | 2012 |
| Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging AU Gurkar, AR Robinson, Y Cui, X Li, SK Allani, A Webster, M Muravia, ... Redox biology 18, 191-199, 2018 | 40 | 2018 |
| Frataxin deficiency promotes endothelial senescence in pulmonary hypertension MK Culley, J Zhao, YY Tai, Y Tang, D Perk, V Negi, Q Yu, CSC Woodcock, ... The Journal of clinical investigation 131 (11), 2021 | 39 | 2021 |
| An alternatively spliced, non-signaling insulin receptor modulates insulin sensitivity via insulin peptide sequestration in C. elegans BA Martinez, P Reis Rodrigues, RM Nuñez Medina, P Mondal, ... Elife 9, e49917, 2020 | 25 | 2020 |
| Methods to quantify the NF-κB pathway during senescence L Zhang, J Zhao, A Gurkar, LJ Niedernhofer, PD Robbins Cellular Senescence: Methods and Protocols, 231-250, 2019 | 23 | 2019 |
| Forestalling age-impaired angiogenesis and blood flow by targeting NOX: Interplay of NOX1, IL-6, and SASP in propagating cell senescence Y Li, D Kračun, CM Dustin, M El Massry, S Yuan, CJ Goossen, ... Proceedings of the National Academy of Sciences 118 (42), e2015666118, 2021 | 21 | 2021 |
| Spatial mapping of cellular senescence: emerging challenges and opportunities AU Gurkar, AA Gerencser, AL Mora, AC Nelson, AR Zhang, AB Lagnado, ... Nature aging 3 (7), 776-790, 2023 | 20 | 2023 |
