NR4A nuclear receptors are orphans but not lonesome K Kurakula, DS Koenis, CM van Tiel, CJM de Vries Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (11), 2543-2555, 2014 | 150 | 2014 |
S100A9 links inflammation and repair in myocardial infarction G Marinković, DS Koenis, L de Camp, R Jablonowski, N Graber, ... Circulation research 127 (5), 664-676, 2020 | 119 | 2020 |
Nuclear receptor Nur77 limits the macrophage inflammatory response through transcriptional reprogramming of mitochondrial metabolism DS Koenis, L Medzikovic, PB van Loenen, M van Weeghel, S Huveneers, ... Cell reports 24 (8), 2127-2140. e7, 2018 | 115 | 2018 |
GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections MB Flak, DS Koenis, A Sobrino, J Smith, K Pistorius, F Palmas, J Dalli The Journal of clinical investigation 130 (1), 359-373, 2020 | 73 | 2020 |
Protein–protein interactions of the LIM-only protein FHL2 and functional implication of the interactions relevant in cardiovascular disease MK Tran, K Kurakula, DS Koenis, CJM de Vries Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (2), 219-228, 2016 | 71 | 2016 |
Disrupted resolution mechanisms favor altered phagocyte responses in COVID-19 DS Koenis, I Beegun, CC Jouvene, GA Aguirre, PR Souza, ... Circulation research 129 (4), e54-e71, 2021 | 49 | 2021 |
USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer JK Nelson, MZ Thin, T Evan, S Howell, M Wu, B Almeida, N Legrave, ... Nature Communications 13 (1), 2070, 2022 | 40 | 2022 |
EEPD1 is a novel LXR target gene in macrophages which regulates ABCA1 abundance and cholesterol efflux JK Nelson, DS Koenis, S Scheij, ECL Cook, M Moeton, A Santos, ... Arteriosclerosis, Thrombosis, and Vascular Biology 37 (3), 423-432, 2017 | 39 | 2017 |
Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance AAJ Hamers, C Argmann, PD Moerland, DS Koenis, G Marinković, ... BMC genomics 17 (1), 1-13, 2016 | 37 | 2016 |
Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene ECL Cook, JK Nelson, V Sorrentino, D Koenis, M Moeton, S Scheij, ... PLoS One 12 (2), e0172721, 2017 | 35 | 2017 |
DLC1 is a direct target of activated YAP/TAZ that drives collective migration and sprouting angiogenesis M van der Stoel, L Schimmel, K Nawaz, AM van Stalborch, A de Haan, ... Journal of cell science 133 (3), jcs239947, 2020 | 34 | 2020 |
LIM-only protein FHL2 is a positive regulator of liver X receptors in smooth muscle cells involved in lipid homeostasis K Kurakula, D Sommer, M Sokolovic, PD Moerland, S Scheij, ... Molecular and cellular biology 35 (1), 52-62, 2015 | 27 | 2015 |
Dual function of Pin1 in NR4A nuclear receptor activation: enhanced activity of NR4As and increased Nur77 protein stability CM van Tiel, K Kurakula, DS Koenis, E van der Wal, CJM de Vries Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (10), 1894-1904, 2012 | 26 | 2012 |
Nur77 protects against adverse cardiac remodelling by limiting neuropeptide Y signalling in the sympathoadrenal-cardiac axis L Medzikovic, C van Roomen, A Baartscheer, PB van Loenen, J de Vos, ... Cardiovascular research 114 (12), 1617-1628, 2018 | 22 | 2018 |
Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity K Kurakula, DS Koenis, MA Herzik Jr, Y Liu, JW Craft Jr, PB van Loenen, ... haematologica 103 (6), 1073, 2018 | 18 | 2018 |
Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans DS Koenis, L Medzikovic, M Vos, TJ Beldman, PB van Loenen, ... Journal of Biological Chemistry 293 (39), 15070-15083, 2018 | 12 | 2018 |
MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis K Pistorius, L Ly, PR Souza, EA Gomez, DS Koenis, AR Rodriguez, ... EBioMedicine 79, 103974, 2022 | 8 | 2022 |
Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation MB Flak, DS Koenis, M Gonzalez-Nunez, A Chopo-Pizarro, J Dalli Biochemical Pharmacology 207, 115348, 2023 | 5 | 2023 |
Dysregulated maresin concentrations in plasma and nasal secretions from patients with chronic rhinosinusitis I Beegun, DS Koenis, G Alusi, J Dalli Frontiers in Immunology 12, 733019, 2021 | 5 | 2021 |
14, 17, 18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae H Jagusch, M Werner, D Koenis, J Dalli, O Werz, G Pohnert ACS Pharmacology & Translational Science 4 (3), 1188-1194, 2021 | 1 | 2021 |