| Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia JAP Spijkers-Hagelstein, S Mimoso Pinhancos, P Schneider, R Pieters, ... Leukemia 27 (5), 1063-1071, 2013 | 62 | 2013 |
| The HDAC inhibitor panobinostat (LBH589) exerts in vivo anti-leukaemic activity against MLL-rearranged acute lymphoblastic leukaemia and involves the RNF20/RNF40/WAC-H2B … P Garrido Castro, EHJ Van Roon, SS Pinhanços, L Trentin, P Schneider, ... Leukemia 32 (2), 323-331, 2018 | 54 | 2018 |
| MEK inhibition is a promising therapeutic strategy for MLL-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations M Kerstjens, EMC Driessen, M Willekes, SS Pinhanços, P Schneider, ... Oncotarget 8 (9), 14835, 2017 | 49 | 2017 |
| AMP-activated protein kinase activation by 5-aminoimidazole-4-carbox-amide-1-β-D-ribofuranoside (AICAR) reduces lipoteichoic acid-induced lung inflammation AJ Hoogendijk, SS Pinhanços, T van der Poll, CW Wieland Journal of Biological Chemistry 288 (10), 7047-7052, 2013 | 48 | 2013 |
| Serum homocysteine: interplay with other circulating and genetic factors in association to Alzheimer's type dementia JF Cascalheira, SS João, SS Pinhanços, R Castro, M Palmeira, ... Clinical biochemistry 42 (9), 783-790, 2009 | 47 | 2009 |
| The HDAC inhibitor panobinostat (LBH589) exerts in vivo anti-leukaemic activity against MLL-rearranged acute lymphoblastic leukaemia and involves the RNF20/RNF40/WAC-H2B … PG Castro, EHJ Van Roon, SS Pinhanços, L Trentin, P Schneider, ... Leukemia 32 (2), 323-323, 2018 | 35 | 2018 |
| Chemical genomic screening identifies LY294002 as a modulator of glucocorticoid resistance in MLL-rearranged infant ALL JAP Spijkers-Hagelstein, SS Pinhanços, P Schneider, R Pieters, ... Leukemia 28 (4), 761-769, 2014 | 32 | 2014 |
| Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo M Kerstjens, SS Pinhancos, PG Castro, P Schneider, P Wander, R Pieters, ... Haematologica 103 (4), e147, 2018 | 30 | 2018 |
| Glucocorticoid sensitisation in Mixed Lineage Leukaemia-rearranged acute lymphoblastic leukaemia by the pan-BCL-2 family inhibitors gossypol and AT-101 JAP Spijkers-Hagelstein, P Schneider, SM Pinhanços, PG Castro, ... European Journal of Cancer 50 (9), 1665-1674, 2014 | 18 | 2014 |
| Intrapulmonary administration of a p38 mitogen activated protein kinase inhibitor partially prevents pulmonary inflammation AJ Hoogendijk, SS Pinhanços, T van der Poll, CW Wieland Immunobiology 218 (4), 435-442, 2013 | 10 | 2013 |
| Versican expression is an adverse prognostic factor in MLL-rearranged infant acute lymphoblastic leukaemia EMC Driessen, SSM Pinhanços, P Schneider, P de Lorenzo, ... European Journal of Cancer 57, 87-90, 2016 | 7 | 2016 |
| Decitabine mildly attenuates MLL‐rearranged acute lymphoblastic leukemia in vivo, and represents a poor chemo‐sensitizer P Schneider, PG Castro, SM Pinhanços, M Kerstjens, EH van Roon, ... EJHaem 1 (2), 527-536, 2020 | 6 | 2020 |
| Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric MLL-Rearranged Acute Lymphoblastic Leukemia M Kerstjens, P Garrido Castro, SS Pinhanços, P Schneider, P Wander, ... Biomedicines 9 (7), 711, 2021 | 3 | 2021 |
| AMP activated protein kinase activation by AICAR reduces lipoteichoic acid induced lung inflammation AJ Hoogendijk, SS Pinhanços, T van der Poll, CW Wieland Kinome activity profiling and kinase modulation of pulmonary inflammation, 103, 2012 | 2 | 2012 |
| Trap1 is expressed in human retinal pigment epithelial cells and is required to maintain their energetic status I Ramos Rego, D Silvério, MI Eufrásio, SS Pinhanços, B Lopes da Costa, ... Antioxidants 12 (2), 381, 2023 | 1 | 2023 |
| Selective inhibition of class II HDAC isoforms 4 and 5 provides a promising therapeutic intervention for MLL-rearranged acute lymphoblastic leukemia in infants TCAI Verbeek, S Arentsen-Peters, PG Castro, S Pinhancos, K Vrenken, ... Blood 138, 2206, 2021 | 1 | 2021 |
| Unravelling the Mirnome of MLL-Rearranged Acute Lymphoblastic Leukemia PG Castro, C Bueno, EHJ van Roon, SSM Pinhancos, P Schneider, ... Blood 124 (21), 878, 2014 | 1 | 2014 |
| IDF23-0097 Use of extracellular vesicles miRNAs as markers of diabetes reversion in metabolic surgery patients J Oliveira, S Pinhanços, T Correia, I Mesquita, M Marcos, P Soares, ... Diabetes Research and Clinical Practice 209, 2024 | | 2024 |
| IDENTIFICATION OF MIRNAS ABLE TO PROTECT CELLS FROM GLUCOLIPOTOXICITY USING A HIGH THROUGHPUT SCREENING APPROACH S Pinhancos, J Oliveira, J Santos, C Alves, M Gotthard, L Ferreira, J Jones, ... WOUND REPAIR AND REGENERATION 31, S53-S53, 2023 | | 2023 |
| IDF2022-0557 High-throughput screening identifies microRNAs capable of rescuing beta cells from glucolipotoxicity-induced cell death S Pinhanços, J Oliveira, J Santos, M Gotthard, L Ferreira, J Jones, ... Diabetes Research and Clinical Practice 197, 2023 | | 2023 |
