Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression M Candolfi, JF Curtin, WS Nichols, AKMG Muhammad, GD King, ... Journal of neuro-oncology 85, 133-148, 2007 | 419 | 2007 |
Controlled drug delivery system for treatment of neural disorders BA Sabel, A Freese, WM Saltzman US Patent 4,883,666, 1989 | 372 | 1989 |
Analysis of harvest morbidity and radiographic outcome using autograft for anterior cervical fusion CL Schnee, A Freese, RJ Weil, PJ Marcotte Spine 22 (19), 2222-2227, 1997 | 337 | 1997 |
Infection of cultured central nervous system neurons with a defective herpes simplex virus 1 vector results in stable expression of Escherichia coli beta-galactosidase. AI Geller, A Freese Proceedings of the National Academy of Sciences 87 (3), 1149-1153, 1990 | 317 | 1990 |
Long-term follow-up after gene therapy for canavan disease P Leone, D Shera, SWJ McPhee, JS Francis, EH Kolodny, LT Bilaniuk, ... Science translational medicine 4 (165), 165ra163-165ra163, 2012 | 300 | 2012 |
Gene Therapy of Canavan Disease: AAV-2 Vector for Neurosurgical Delivery of Aspartoacylase Gene (ASPA) to the Human Brain C Janson, S McPhee, L Bilaniuk, J Haselgrove, M Testaiuti, A Freese, ... Human gene therapy 13 (11), 1391-1412, 2002 | 297 | 2002 |
Immune responses to AAV in a phase I study for Canavan disease SWJ McPhee, CG Janson, C Li, RJ Samulski, AS Camp, J Francis, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2006 | 286 | 2006 |
Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors KJ Swartz, MJ During, A Freese, MF Beal Journal of Neuroscience 10 (9), 2965-2973, 1990 | 281 | 1990 |
Controlled release of dopamine from a polymeric brain implant: in vivo characterization MJ During, A Freese, BA Sabel, WM Saltzman, A Deutch, RH Roth, ... Annals of Neurology: Official Journal of the American Neurological …, 1989 | 281 | 1989 |
Long-term increases in neurotransmitter release from neuronal cells expressing a constitutively active adenylate cyclase from a herpes simplex virus type 1 vector. AI Geller, MJ During, JW Haycock, A Freese, R Neve Proceedings of the National Academy of Sciences 90 (16), 7603-7607, 1993 | 246 | 1993 |
An HSV‐1 Vector Expressing Tyrosine Hydroxylase Causes Production and Release of l‐DOPA from Cultured Rat Striatal Cells AI Geller, MJ During, YJ Oh, A Freese, K O'Malley Journal of neurochemistry 64 (2), 487-496, 1995 | 216 | 1995 |
In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector MJ During, RJ Samulski, JD Elsworth, MG Kaplitt, P Leone, X Xiao, J Li, ... Gene Therapy 5 (6), 820-827, 1998 | 212 | 1998 |
Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease P Leone, CG Janson, L Bilianuk, Z Wang, F Sorgi, L Huang, R Matalon, ... Annals of neurology 48 (1), 27-38, 2000 | 204 | 2000 |
Outcome analysis for adults with spondylolisthesis treated with posterolateral fusion and transpedicular screw fixation CL Schnee, A Freese, LV Ansell Journal of neurosurgery 86 (1), 56-63, 1997 | 169 | 1997 |
Basic fibroblast growth factor protects striatal neurons in vitro from NMDA-receptor mediated excitotoxicity A Freese, SP Finklestein, M DiFiglia Brain research 575 (2), 351-355, 1992 | 169 | 1992 |
Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing … JR Ohlfest, ZL Demorest, Y Motooka, I Vengco, S Oh, E Chen, ... Molecular Therapy 12 (5), 778-788, 2005 | 162 | 2005 |
Kynurenine metabolites of tryptophan: implications for neurologic diseases A Freese, KJ Swartz, MJ During, JB Martin, MD, PhD Neurology 40 (4), 691-691, 1990 | 107 | 1990 |
Extended drug delivery of small, water-soluble molecules BA Sabel, A Freese US Patent 5,114,719, 1992 | 105 | 1992 |
HSV-1 vector mediated neuronal gene delivery strategies for molecular neuroscience and neurology A Freese, AI Geller, R Neve Biochemical pharmacology 40 (10), 2189-2199, 1990 | 97 | 1990 |
Stimulation of choline release from NG108-15 cells by 12-O-tetradecanoylphorbol 13-acetate M Liscovitch, JK Blusztajn, A Freese, RJ Wurtman Biochemical Journal 241 (1), 81-86, 1987 | 97 | 1987 |