Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library S Ahn, AW Kahsai, B Pani, QT Wang, S Zhao, AL Wall, RT Strachan, ... Proceedings of the National Academy of Sciences 114 (7), 1708-1713, 2017 | 133 | 2017 |
Single cell analysis of human tissues and solid tumors with mass cytometry N Leelatian, DB Doxie, AR Greenplate, BC Mobley, JM Lehman, ... Cytometry Part B: Clinical Cytometry 92 (1), 68-78, 2017 | 111 | 2017 |
Preparing viable single cells from human tissue and tumors for cytomic analysis N Leelatian, DB Doxie, AR Greenplate, J Sinnaeve, RA Ihrie, JM Irish Current protocols in molecular biology 118 (1), 25C. 1.1-25C. 1.23, 2017 | 55 | 2017 |
Space invaders: brain tumor exploitation of the stem cell niche J Sinnaeve, BC Mobley, RA Ihrie The American journal of pathology 188 (1), 29-38, 2018 | 24 | 2018 |
Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells N Leelatian, J Sinnaeve, AM Mistry, SM Barone, AA Brockman, ... Elife 9, e56879, 2020 | 20 | 2020 |
DEPDC5 haploinsufficiency drives increased mTORC1 signaling and abnormal morphology in human iPSC-derived cortical neurons LK Klofas, BP Short, JP Snow, J Sinnaeve, GV Rushing, G Westlake, ... Neurobiology of disease 143, 104975, 2020 | 19 | 2020 |
Induction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulin B Singh, G Bogatcheva, A Starchenko, J Sinnaeve, LA Lapierre, ... Journal of Cell Science 128 (18), 3444-3455, 2015 | 12 | 2015 |
An immunosuppressed microenvironment distinguishes lateral ventricle–contacting glioblastomas T Bartkowiak, SM Lima, MJ Hayes, AM Mistry, AA Brockman, J Sinnaeve, ... JCI insight 8 (12), 2023 | 4 | 2023 |
High risk glioblastoma cells revealed by machine learning and single cell signaling profiles N Leelatian, J Sinnaeve, AM Mistry, SM Barone, KE Diggins, ... bioRxiv, 632208, 2019 | 3 | 2019 |
IMMU-16. TWO DISTINCT SUBSETS OF NATURAL KILLER CELLS ARE ENRICHED IN THE TUMOR MICROENVIRONMENT AND CORRELATE WITH SURVIVAL OUTCOME IN HUMAN GLIOBLASTOMA. T Bartkowiak, S Barone, M Hayes, C Roe, J Sinnaeve, A Mistry, ... Neuro-Oncology 22 (Supplement_2), ii107-ii108, 2020 | 1 | 2020 |
CSIG-19. DETECTION OF IDH1 R132H VIA FLOW CYTOMETRY IN INTRAOPERATIVE AND ARCHIVAL GLIOMA SPECIMENS IN IDH, WT GRADE II Neuro-Oncology, 2018 | 1 | 2018 |
Mass cytometry of human glioblastoma characterizes more than 99 percent of cells and reveals intratumoral cell subsets defined by contrasting signaling network profiles N Leelatian, J Sinnaeve, BC Mobley, AM Mistry, D Liu, KD Weaver, ... Cancer Research 77 (13_Supplement), 364-364, 2017 | 1 | 2017 |
TMIC-26. USING INTEGRATED MULTIDIMENSIONAL MASS CYTOMETRY AND MULTIPLEX IMMUNOHISTOCHEMISTRY TO INFER SPATIAL RELATIONSHIPS BETWEEN PHENOTYPICALLY DISTINCT GLIOBLASTOMA … T Bartkowiak, A Brockman, S Lima, M Hayes, C Roe, J Sinnaeve, A Mistry, ... Neuro-Oncology 24 (Supplement_7), vii277-vii277, 2022 | | 2022 |
Immune cell regulation in stem cell niche contacting glioblastomas T Bartkowiak, SM Lima, MJ Hayes, AM Mistry, J Sinnaeve, N Leelatian, ... bioRxiv, 2022.02. 16.480731, 2022 | | 2022 |
111 Integrating multidimensional mass cytometry and multiplex immunohistochemistry to infer spatial relationships between human glioblastoma infiltrating immune cells that … T Bartkowiak, A Brockman, S Lima, M Hayes, C Roe, J Sinnaeve, A Mistry, ... J Immunother 10 (2), A1-A1595, 2022 | | 2022 |
SELECTIVE ENRICHMENT OF SUPPRESSED IMMUNE CELLS IN THE TUMOR MICROENVIRONMENT CORRELATES WITH ESTABLISHMENT OF DISTINCT IMMUNOLOGIC NICHES IN HUMAN GLIOBLASTOMAS CONTACTING THE … T Bartkowiak, A Brockman, B Mobley, A Mistry, S Barone, M Hayes, C Roe, ... NEURO-ONCOLOGY 23, 94-94, 2021 | | 2021 |
38 Spatial immune profiling of human glioblastoma tissue reveals the presence of aggregated lymphoid niches in the tumor microenvironment T Bartkowiak, A Brockman, S Barone, M Hayes, C Roe, J Sinnaeve, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A45-A45, 2021 | | 2021 |
661 Five immunotypic signatures identified in human glioblastoma correlate with tumor contact with the lateral ventricle, immune suppression, and patient outcome T Bartkowiak, S Barone, M Hayes, A Greenplate, J Sinnaeve, N Leelatian, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | | 2020 |
Single-cell systems neuroimmunology reveals a highly immunosuppressive microenvironment in human glioblastomas contacting the ventricular stem cell niche T Bartkowiak, S Barone, AM Mistry, AR Greenplate, J Sinnaeve, ... The Journal of Immunology 204 (1_Supplement), 242.23-242.23, 2020 | | 2020 |
Single Cell Studies of Protein Expression Reveal Glioma Cell Phenotypes and Prognostic Tumor Cell Populations J Sinnaeve Vanderbilt University, 2020 | | 2020 |