| N6-methyladenosine in flaviviridae viral RNA genomes regulates infection NS Gokhale, ABR McIntyre, MJ McFadden, AE Roder, EM Kennedy, ... Cell host & microbe 20 (5), 654-665, 2016 | 435 | 2016 |
| Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition CL Holley, MR Olson, DA Colón-Ramos, S Kornbluth Nature cell biology 4 (6), 439-444, 2002 | 266 | 2002 |
| Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress CI Michel, CL Holley, BS Scruggs, R Sidhu, RT Brookheart, ... Cell metabolism 14 (1), 33-44, 2011 | 250 | 2011 |
| Epitranscriptomic addition of m5C to HIV-1 transcripts regulates viral gene expression DG Courtney, K Tsai, HP Bogerd, EM Kennedy, BA Law, A Emery, ... Cell host & microbe 26 (2), 217-227. e6, 2019 | 149 | 2019 |
| Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivo BA Elliott, HT Ho, SV Ranganathan, S Vangaveti, O Ilkayeva, H Abou Assi, ... Nature communications 10 (1), 3401, 2019 | 149 | 2019 |
| Altered m6A modification of specific cellular transcripts affects flaviviridae infection NS Gokhale, ABR McIntyre, MD Mattocks, CL Holley, HM Lazear, ... Molecular cell 77 (3), 542-555. e8, 2020 | 144 | 2020 |
| Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis KS McCommis, WT Hodges, EM Brunt, I Nalbantoglu, WG McDonald, ... Hepatology 65 (5), 1543-1556, 2017 | 129 | 2017 |
| An introduction to small non-coding RNAs: miRNA and snoRNA CL Holley, VK Topkara Cardiovascular drugs and therapy 25, 151-159, 2011 | 118 | 2011 |
| Prognostic utility of novel biomarkers of cardiovascular stress in patients with aortic stenosis undergoing valve replacement BR Lindman, JG Breyley, JD Schilling, AM Vatterott, A Zajarias, ... Heart 101 (17), 1382-1388, 2015 | 111 | 2015 |
| N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs NJ Fry, BA Law, OR Ilkayeva, CL Holley, KD Mansfield Rna 23 (9), 1444-1455, 2017 | 105 | 2017 |
| Reaper is regulated by IAP-mediated ubiquitination MR Olson, CL Holley, SJ Yoo, JR Huh, BA Hay, S Kornbluth Journal of Biological Chemistry 278 (6), 4028-4034, 2003 | 103 | 2003 |
| Rpl13a small nucleolar RNAs regulate systemic glucose metabolism J Lee, AN Harris, CL Holley, J Mahadevan, KD Pyles, Z Lavagnino, ... The Journal of clinical investigation 126 (12), 4616-4625, 2016 | 84 | 2016 |
| A GH3-like domain in reaper is required for mitochondrial localization and induction of IAP degradation MR Olson, CL Holley, EC Gan, DA Colón-Ramos, B Kaplan, S Kornbluth Journal of Biological Chemistry 278 (45), 44758-44768, 2003 | 78 | 2003 |
| 2′-O-Methylation can increase the abundance and lifetime of alternative RNA conformational states H Abou Assi, AK Rangadurai, H Shi, B Liu, MC Clay, K Erharter, C Kreutz, ... Nucleic acids research 48 (21), 12365-12379, 2020 | 75 | 2020 |
| Cytosolic accumulation of small nucleolar RNAs (snoRNAs) is dynamically regulated by NADPH oxidase CL Holley, MW Li, BS Scruggs, SJ Matkovich, DS Ory, JE Schaffer Journal of Biological Chemistry 290 (18), 11741-11748, 2015 | 75 | 2015 |
| Noncoding RNAs in cardiovascular disease: current knowledge, tools and technologies for investigation, and future directions: a scientific statement from the american heart … S Das, R Shah, S Dimmeler, JE Freedman, C Holley, JM Lee, K Moore, ... Circulation: Genomic and Precision Medicine 13 (4), e000062, 2020 | 69 | 2020 |
| Long-range function of secreted small nucleolar RNAs that direct 2′-O-methylation JM Rimer, J Lee, CL Holley, RJ Crowder, DL Chen, PI Hanson, DS Ory, ... Journal of Biological Chemistry 293 (34), 13284-13296, 2018 | 60 | 2018 |
| RoBo-1, a novel member of the urokinase plasminogen activator receptor/CD59/Ly-6/snake toxin family selectively expressed in rat bone and growth plate cartilage LS Noel, BR Champion, CL Holley, CJ Simmons, DC Morris, JA Payne, ... Journal of Biological Chemistry 273 (7), 3878-3883, 1998 | 54 | 1998 |
| Extensive epitranscriptomic methylation of A and C residues on murine leukemia virus transcripts enhances viral gene expression DG Courtney, A Chalem, HP Bogerd, BA Law, EM Kennedy, CL Holley, ... MBio 10 (3), 10.1128/mbio. 01209-19, 2019 | 49 | 2019 |
| N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression NJ Fry, BA Law, OR Ilkayeva, KR Carraway, CL Holley, KD Mansfield Oncotarget 9 (58), 31231, 2018 | 33 | 2018 |
Edward KennedyOncorus Inc.Verified email at oncorus.com
