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Patrick O'Leary
Patrick O'Leary
Verified email at ucsf.edu
Title
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Cited by
Year
A protein interaction landscape of breast cancer
M Kim, J Park, M Bouhaddou, K Kim, A Rojc, M Modak, M Soucheray, ...
Science 374 (6563), eabf3066, 2021
782021
RASA2 ablation in T cells boosts antigen sensitivity and long-term function
J Carnevale, E Shifrut, N Kale, WA Nyberg, F Blaeschke, YY Chen, Z Li, ...
Nature 609 (7925), 174-182, 2022
722022
Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer
PC O’Leary, M Terrile, M Bajor, P Gaj, BT Hennessy, GB Mills, ...
Breast Cancer Research 16, 1-15, 2014
632014
Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer
PC O'Leary, SA Penny, RT Dolan, CM Kelly, SF Madden, E Rexhepaj, ...
BMC cancer 13 (1), 1-13, 2013
582013
Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents
M Bajor, AO Zych, A Graczyk-Jarzynka, A Muchowicz, M Firczuk, ...
British Journal of Cancer 119 (7), 873-884, 2018
532018
Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL
AJ Eustace, NT Conlon, MSJ McDermott, BC Browne, P O’Leary, ...
Bmc Cancer 18, 1-14, 2018
332018
Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis
D Ryan, M Rafferty, S Hegarty, P O’Leary, W Faller, G Gremel, ...
Pigment cell & melanoma research 23 (4), 542-553, 2010
282010
High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients
K van den Hurk, B Balint, S Toomey, PC O’Leary, L Unwin, K Sheahan, ...
Melanoma Research 25 (3), 189-199, 2015
172015
Generation of a new bioluminescent model for visualisation of mammary tumour development in transgenic mice
AM Zagozdzon, P O’Leary, JJ Callanan, J Crown, WM Gallagher, ...
BMC cancer 12, 1-10, 2012
132012
A whole-genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
H Chen, ME Diolaiti, PC O'Leary, A Rojc, NJ Krogan, M Kim, A Ashworth
Molecular cancer therapeutics 21 (7), 1076-1089, 2022
82022
Resistance to ATR inhibitors is mediated by loss of the nonsense-mediated decay factor UPF2
PC O'Leary, H Chen, YU Doruk, T Williamson, B Polacco, AS McNeal, ...
Cancer research 82 (21), 3950-3961, 2022
72022
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo
TY Taha, RK Suryawanshi, IP Chen, GJ Correy, M McCavitt-Malvido, ...
PLoS Pathogens 19 (8), e1011614, 2023
52023
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo
TY Taha, RK Suryawanshi, IP Chen, GJ Correy, PC O’Leary, ...
bioRxiv, 2023
22023
Adenanthin, a new peroxiredoxin inhibitor, induces a switch between estrogen receptor alpha-mediated and Src/Akt-driven signaling in breast cancer cells
M Bajor, AO Zych, PC O'Leary, A Czekalska, WM Gallagher, J Golab, ...
CANCER RESEARCH 75, 2015
22015
Large tandem duplications in cancer result from transcription and DNA replication collisions
Y Yang, ML Badura, PC O’Leary, HM Delavan, TM Robinson, EA Egusa, ...
medRxiv, 2023.05. 17.23290140, 2023
12023
Abstract P6-06-01: Analyzing the physical and functional protein interaction landscape of breast cancer
M Kim, K Kim, B Tutuncuoglu, M Soucheray, D Swaney, F Zheng, J Park, ...
Cancer Research 79 (4_Supplement), P6-06-01-P6-06-01, 2019
2019
Targeting BRCAness in Gastric Cancer
A Ashworth, P O'Leary, ...
2018
ROLE OF THIOL-DEPENDENT PEROXIREDOXINS IN REGULATION OF AKT SIGNALING IN BREAST CANCER
M Bajor, PC O'Leary, AO Zych, WM Gallagher, J Golab, R Zagozdzon
Journal of International Society of Antioxidants in Nutrition & Health 1 (1), 2016
2016
Abstract P5-07-09: Adenanthin, a new peroxiredoxin inhibitor, induces a switch between estrogen receptor alpha-mediated and Src/Akt-driven signaling in breast cancer cells
M Bajor, AO Zych, PC O'Leary, A Czekalska, WM Gallagher, J Golab, ...
Cancer Research 75 (9_Supplement), P5-07-09-P5-07-09, 2015
2015
Multi-platform Validation and Functional Interrogation of Peroxiredoxin 1 as a Prognostic Cancer Biomarker
P O'Leary
University College Dublin, 2013
2013
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