| Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch BL Oakes, DC Nadler, A Flamholz, C Fellmann, BT Staahl, JA Doudna, ... Nature biotechnology 34 (6), 646-651, 2016 | 209 | 2016 |
| Identification and characterization of a multidomain hyperthermophilic cellulase from an archaeal enrichment JE Graham, ME Clark, DC Nadler, S Huffer, HA Chokhawala, SE Rowland, ... Nature communications 2 (1), 375, 2011 | 175 | 2011 |
| Rapid construction of metabolite biosensors using domain-insertion profiling DC Nadler, SA Morgan, A Flamholz, KE Kortright, DF Savage Nature communications 7 (1), 12266, 2016 | 114 | 2016 |
| CRISPR-Cas9 circular permutants as programmable scaffolds for genome modification BL Oakes, C Fellmann, H Rishi, KL Taylor, SM Ren, DC Nadler, R Yokoo, ... Cell 176 (1), 254-267. e16, 2019 | 106 | 2019 |
| Binding modules alter the activity of chimeric cellulases: effects of biomass pretreatment and enzyme source TW Kim, HA Chokhawala, DC Nadler, HW Blanch, DS Clark Biotechnology and bioengineering 107 (4), 601-611, 2010 | 50 | 2010 |
| Biofuel metabolic engineering with biosensors SA Morgan, DC Nadler, R Yokoo, DF Savage Current Opinion in Chemical Biology 35, 150-158, 2016 | 42 | 2016 |
| Protein engineering of Cas9 for enhanced function BL Oakes, DC Nadler, DF Savage Methods in enzymology 546, 491-511, 2014 | 34 | 2014 |
| High-throughput screening for high-efficiency small-molecule biosynthesis M Rienzo, SJ Jackson, LK Chao, T Leaf, TJ Schmidt, AH Navidi, ... Metabolic Engineering 63, 102-125, 2021 | 33 | 2021 |
| Variant Cas9 polypeptides comprising internal insertions B Oakes, D Savage, D Nadler, AI Flamholz, JA Doudna US Patent 11,008,555, 2021 | 1 | 2021 |
| BIOT 312-Developing improved thermostable cellulases: High-throughput cellulolytic assays and protein engineering strategies HA Chokhawala, TW Kim, CM Dana, DC Nadler, HW Blanch, DS Clark ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 238, 2009 | | 2009 |
| Developing Improved Thermostable Cellulases: High-Throughput Cellulolytic Assays and Protein Engineering Strategies AC Harshal, TW Kim, C Dana, DC Nadler, HW Blanch, DS Clark The 31st Symposium on Biotechnology for Fuels and Chemicals, 2009 | | 2009 |
| Kinetics and Synergy of Trichoderma reesei Cellulases on Ionic Liquid Pretreated Avicel and Miscanthus giganticus J Fox, AC Harshal, C Dana, DC Nadler, P Wolski, HW Blanch, DS Clark The 31st Symposium on Biotechnology for Fuels and Chemicals, 2009 | | 2009 |
David SavageAssoc. Prof. of Molecular & Cell Biology, UC Berkeley; Investigator, Howard Hughes Medical InstituteVerified email at berkeley.edu
