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Salomao Doria Jorge
Salomao Doria Jorge
Verified email at mcw.edu
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Year
The roles of ROS in cancer heterogeneity and therapy
PL de Sá Junior, DAD Câmara, AS Porcacchia, PMM Fonseca, SD Jorge, ...
Oxidative medicine and cellular longevity 2017, 2017
2472017
Design, synthesis, antimicrobial activity and molecular modeling studies of novel benzofuroxan derivatives against Staphylococcus aureus
SD Jorge, A Masunari, CO Rangel-Yagui, KFM Pasqualoto, LC Tavares
Bioorganic & medicinal chemistry 17 (8), 3028-3036, 2009
722009
Synthesis, molecular modeling and preliminary biological evaluation of a set of 3-acetyl-2, 5-disubstituted-2, 3-dihydro-1, 3, 4-oxadiazole as potential antibacterial, anti …
M Ishii, SD Jorge, AA de Oliveira, F Palace-Berl, IY Sonehara, ...
Bioorganic & medicinal chemistry 19 (21), 6292-6301, 2011
592011
Novel benzofuroxan derivatives against multidrug-resistant Staphylococcus aureus strains: Design using Topliss’ decision tree, synthesis and biological assay
SD Jorge, F Palace-Berl, A Masunari, CA Cechinel, M Ishii, ...
Bioorganic & medicinal chemistry 19 (16), 5031-5038, 2011
392011
Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis
RR Zorzi, SD Jorge, F Palace-Berl, KFM Pasqualoto, L de Sá Bortolozzo, ...
Bioorganic & medicinal chemistry 22 (10), 2844-2854, 2014
362014
5-Nitro-2-furfuriliden derivatives as potential anti-Trypanosoma cruzi agents: Design, synthesis, bioactivity evaluation, cytotoxicity and exploratory data analysis
F Palace-Berl, SD Jorge, KFM Pasqualoto, AK Ferreira, DA Maria, ...
Bioorganic & medicinal chemistry 21 (17), 5395-5406, 2013
322013
Designing and exploring active N′-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against three Trypanosoma cruzi strains more prevalent in Chagas disease patients
F Palace-Berl, KFM Pasqualoto, SD Jorge, B Zingales, RR Zorzi, MN Silva, ...
European journal of medicinal chemistry 96, 330-339, 2015
292015
Ligand-based design, synthesis, and experimental evaluation of novel benzofuroxan derivatives as anti-Trypanosoma cruzi agents
SD Jorge, F Palace-Berl, KFM Pasqualoto, M Ishii, AK Ferreira, CM Berra, ...
European journal of medicinal chemistry 64, 200-214, 2013
292013
Molecular modeling studies and in vitro bioactivity evaluation of a set of novel 5-nitro-heterocyclic derivatives as anti-T. cruzi agents
FR Paula, SD Jorge, LV de Almeida, KFM Pasqualoto, LC Tavares
Bioorganic & medicinal chemistry 17 (7), 2673-2679, 2009
292009
Benzofuroxan derivatives N-Br and NI induce intrinsic apoptosis in melanoma cells by regulating AKT/BIM signaling and display anti metastatic activity in vivo
CF Farias, MH Massaoka, N Girola, RA Azevedo, AK Ferreira, SD Jorge, ...
BMC cancer 15, 1-11, 2015
182015
Preliminary in vitro evaluation of N′-(benzofuroxan-5-yl) methylene benzohydrazide derivatives as potential anti-Trypanosoma cruzi agents
SD Jorge, M Ishii, F Palace-Berl, AK Ferreira, PL de Sa Junior, ...
MedChemComm 3 (7), 824-828, 2012
172012
BFD-22 a new potential inhibitor of BRAF inhibits the metastasis of B16F10 melanoma cells and simultaneously increased the tumor immunogenicity
AK Ferreira, KFM Pasqualoto, FAE Kruyt, F Palace-Berl, RA Azevedo, ...
Toxicology and Applied Pharmacology 295, 56-67, 2016
142016
Synergistic anti-tumor effects of the combination of a benzofuroxan derivate and sorafenib on NCI-H460 human large cell lung carcinoma cells
SF Teixeira, RA de Azevedo, MAC Salomon, SD Jorge, D Levy, ...
Biomedicine & Pharmacotherapy 68 (8), 1015-1022, 2014
92014
Edelfosine: An antitumor drug prototype
SF Teixeira, CP Rodrigues, CJS Costa, TN Pettinati, RA de Azevedo, ...
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018
72018
Phosphoethanolamine induces caspase-independent cell death by reducing the expression of C-RAF and inhibits tumor growth in human melanoma model
LI Mambelli, SF Teixeira, SD Jorge, B Kawamura, R Meneguelo, ...
Biomedicine & Pharmacotherapy 103, 18-28, 2018
52018
Evaluation of cytotoxic effect of the combination of a pyridinyl carboxamide derivative and oxaliplatin on NCI-H1299 human non-small cell lung carcinoma cells
SF Teixeira, RA de Azevedo, AC Silva, RC Braga, SD Jorge, JAM Barbuto, ...
Biomedicine & Pharmacotherapy 84, 1019-1028, 2016
52016
Síntese e avaliação da atividade antibacteriana de derivados 5-metilsulfonil-2-tiofilidênicos e de derivados 5 (6)-benzofuroxânicos frente a cepas padrão e multi-resistente de …
SD Jorge
Universidade de São Paulo, 2007
42007
Topliss decision-tree approach applied in the design of new benzofuroxan derivatives with antimicrobial activity against multidrug-resistant Staphylococcus aureus strains
FP Berl, A Masunari, SD Jorge, CA Cechinel, M Ishii, LC Tavares
Brazilian Journal of Pharmaceutical Sciences 45, 67, 2009
22009
Integrative modeling, molecular mechanics, and molecular dynamics evaluation of genomics variants in KMT2C (MLL3), a gene involved in Kleefstra Syndrome Type 2
SD Jorge, YI Chi, TM de Assuncao, AJ Mathison, B Volkman, B Smith, ...
The FASEB Journal 36, 2022
12022
Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction
SD Jorge, YI Chi, JL Mazaba, N Haque, J Wagenknecht, BC Smith, ...
Frontiers in Genetics 14, 1291307, 2023
2023
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