The roles of ROS in cancer heterogeneity and therapy PL de Sá Junior, DAD Câmara, AS Porcacchia, PMM Fonseca, SD Jorge, ... Oxidative medicine and cellular longevity 2017, 2017 | 247 | 2017 |
Design, synthesis, antimicrobial activity and molecular modeling studies of novel benzofuroxan derivatives against Staphylococcus aureus SD Jorge, A Masunari, CO Rangel-Yagui, KFM Pasqualoto, LC Tavares Bioorganic & medicinal chemistry 17 (8), 3028-3036, 2009 | 72 | 2009 |
Synthesis, molecular modeling and preliminary biological evaluation of a set of 3-acetyl-2, 5-disubstituted-2, 3-dihydro-1, 3, 4-oxadiazole as potential antibacterial, anti … M Ishii, SD Jorge, AA de Oliveira, F Palace-Berl, IY Sonehara, ... Bioorganic & medicinal chemistry 19 (21), 6292-6301, 2011 | 59 | 2011 |
Novel benzofuroxan derivatives against multidrug-resistant Staphylococcus aureus strains: Design using Topliss’ decision tree, synthesis and biological assay SD Jorge, F Palace-Berl, A Masunari, CA Cechinel, M Ishii, ... Bioorganic & medicinal chemistry 19 (16), 5031-5038, 2011 | 39 | 2011 |
Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis RR Zorzi, SD Jorge, F Palace-Berl, KFM Pasqualoto, L de Sá Bortolozzo, ... Bioorganic & medicinal chemistry 22 (10), 2844-2854, 2014 | 36 | 2014 |
5-Nitro-2-furfuriliden derivatives as potential anti-Trypanosoma cruzi agents: Design, synthesis, bioactivity evaluation, cytotoxicity and exploratory data analysis F Palace-Berl, SD Jorge, KFM Pasqualoto, AK Ferreira, DA Maria, ... Bioorganic & medicinal chemistry 21 (17), 5395-5406, 2013 | 32 | 2013 |
Designing and exploring active N′-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against three Trypanosoma cruzi strains more prevalent in Chagas disease patients F Palace-Berl, KFM Pasqualoto, SD Jorge, B Zingales, RR Zorzi, MN Silva, ... European journal of medicinal chemistry 96, 330-339, 2015 | 29 | 2015 |
Ligand-based design, synthesis, and experimental evaluation of novel benzofuroxan derivatives as anti-Trypanosoma cruzi agents SD Jorge, F Palace-Berl, KFM Pasqualoto, M Ishii, AK Ferreira, CM Berra, ... European journal of medicinal chemistry 64, 200-214, 2013 | 29 | 2013 |
Molecular modeling studies and in vitro bioactivity evaluation of a set of novel 5-nitro-heterocyclic derivatives as anti-T. cruzi agents FR Paula, SD Jorge, LV de Almeida, KFM Pasqualoto, LC Tavares Bioorganic & medicinal chemistry 17 (7), 2673-2679, 2009 | 29 | 2009 |
Benzofuroxan derivatives N-Br and NI induce intrinsic apoptosis in melanoma cells by regulating AKT/BIM signaling and display anti metastatic activity in vivo CF Farias, MH Massaoka, N Girola, RA Azevedo, AK Ferreira, SD Jorge, ... BMC cancer 15, 1-11, 2015 | 18 | 2015 |
Preliminary in vitro evaluation of N′-(benzofuroxan-5-yl) methylene benzohydrazide derivatives as potential anti-Trypanosoma cruzi agents SD Jorge, M Ishii, F Palace-Berl, AK Ferreira, PL de Sa Junior, ... MedChemComm 3 (7), 824-828, 2012 | 17 | 2012 |
BFD-22 a new potential inhibitor of BRAF inhibits the metastasis of B16F10 melanoma cells and simultaneously increased the tumor immunogenicity AK Ferreira, KFM Pasqualoto, FAE Kruyt, F Palace-Berl, RA Azevedo, ... Toxicology and Applied Pharmacology 295, 56-67, 2016 | 14 | 2016 |
Synergistic anti-tumor effects of the combination of a benzofuroxan derivate and sorafenib on NCI-H460 human large cell lung carcinoma cells SF Teixeira, RA de Azevedo, MAC Salomon, SD Jorge, D Levy, ... Biomedicine & Pharmacotherapy 68 (8), 1015-1022, 2014 | 9 | 2014 |
Edelfosine: An antitumor drug prototype SF Teixeira, CP Rodrigues, CJS Costa, TN Pettinati, RA de Azevedo, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 7 | 2018 |
Phosphoethanolamine induces caspase-independent cell death by reducing the expression of C-RAF and inhibits tumor growth in human melanoma model LI Mambelli, SF Teixeira, SD Jorge, B Kawamura, R Meneguelo, ... Biomedicine & Pharmacotherapy 103, 18-28, 2018 | 5 | 2018 |
Evaluation of cytotoxic effect of the combination of a pyridinyl carboxamide derivative and oxaliplatin on NCI-H1299 human non-small cell lung carcinoma cells SF Teixeira, RA de Azevedo, AC Silva, RC Braga, SD Jorge, JAM Barbuto, ... Biomedicine & Pharmacotherapy 84, 1019-1028, 2016 | 5 | 2016 |
Síntese e avaliação da atividade antibacteriana de derivados 5-metilsulfonil-2-tiofilidênicos e de derivados 5 (6)-benzofuroxânicos frente a cepas padrão e multi-resistente de … SD Jorge Universidade de São Paulo, 2007 | 4 | 2007 |
Topliss decision-tree approach applied in the design of new benzofuroxan derivatives with antimicrobial activity against multidrug-resistant Staphylococcus aureus strains FP Berl, A Masunari, SD Jorge, CA Cechinel, M Ishii, LC Tavares Brazilian Journal of Pharmaceutical Sciences 45, 67, 2009 | 2 | 2009 |
Integrative modeling, molecular mechanics, and molecular dynamics evaluation of genomics variants in KMT2C (MLL3), a gene involved in Kleefstra Syndrome Type 2 SD Jorge, YI Chi, TM de Assuncao, AJ Mathison, B Volkman, B Smith, ... The FASEB Journal 36, 2022 | 1 | 2022 |
Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction SD Jorge, YI Chi, JL Mazaba, N Haque, J Wagenknecht, BC Smith, ... Frontiers in Genetics 14, 1291307, 2023 | | 2023 |