| Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection J Fantini, C Di Scala, H Chahinian, N Yahi International journal of antimicrobial agents 55 (5), 105960, 2020 | 647 | 2020 |
| Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein C Di Scala, N Yahi, S Boutemeur, A Flores, L Rodriguez, H Chahinian, ... Scientific reports 6 (1), 28781, 2016 | 176 | 2016 |
| Interaction of Alzheimer’s β-amyloid peptides with cholesterol: Mechanistic insights into amyloid pore formation C Di Scala, H Chahinian, N Yahi, N Garmy, J Fantini Biochemistry 53 (28), 4489-4502, 2014 | 152 | 2014 |
| Distinction between esterases and lipases: a kinetic study with vinyl esters and TAG H Chahinian, L Nini, E Boitard, JP Dubès, LC Comeau, L Sarda Lipids 37 (7), 653-662, 2002 | 131 | 2002 |
| Production of Extracellular Lipases by Penicillium cyclopium Purification and Characterization of a Partial Acylglycerol Lipase H Chahinian, G Vanot, A Ibrik, N RUGANI, L SARDA, LC COMEAU Bioscience, biotechnology, and biochemistry 64 (2), 215-222, 2000 | 129 | 2000 |
| Distinction between esterases and lipases: comparative biochemical properties of sequence-related carboxylesterases SL Chahinian H Protein Pept Lett. 16 (10), 1149-61, 2009 | 128 | 2009 |
| Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: what molecular dynamics studies of virus-host interactions reveal J Fantini, H Chahinian, N Yahi International Journal of Antimicrobial Agents, 106020, 2020 | 127 | 2020 |
| Characterization of an exported monoglyceride lipase from Mycobacterium tuberculosis possibly involved in the metabolism of host cell membrane lipids K Côtes, R Dhouib, I Douchet, H Chahinian, A De Caro, F Carrière, ... Biochemical Journal 408 (3), 417-427, 2007 | 112 | 2007 |
| Mechanism of cholesterol‐assisted oligomeric channel formation by a short Alzheimer β‐amyloid peptide C Di Scala, JD Troadec, C Lelièvre, N Garmy, J Fantini, H Chahinian Journal of neurochemistry 128 (1), 186-195, 2014 | 106 | 2014 |
| Lipase-catalysed hydrolysis of short-chain substrates in solution and in emulsion: a kinetic study L Nini, L Sarda, LC Comeau, E Boitard, JP Dubès, H Chahinian Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2001 | 101 | 2001 |
| The puzzling mutational landscape of the SARS‐2‐variant Omicron J Fantini, N Yahi, P Colson, H Chahinian, B La Scola, D Raoult Journal of medical virology 94 (5), 2019-2025, 2022 | 94 | 2022 |
| Structural dynamics of SARS-CoV-2 variants: A health monitoring strategy for anticipating Covid-19 outbreaks J Fantini, N Yahi, F Azzaz, H Chahinian Journal of Infection 83 (2), 197-206, 2021 | 88 | 2021 |
| Bexarotene blocks calcium-permeable ion channels formed by neurotoxic Alzheimer’s β-amyloid peptides J Fantini, C Di Scala, N Yahi, JD Troadec, K Sadelli, H Chahinian, ... ACS Chemical Neuroscience 5 (3), 216-224, 2014 | 83 | 2014 |
| Expression and characterization of the protein Rv1399c from Mycobacterium tuberculosis A novel carboxyl esterase structurally related to the HSL family S Canaan, D Maurin, H Chahinian, B Pouilly, C Durousseau, F Frassinetti, ... European Journal of Biochemistry 271 (19), 3953-3961, 2004 | 83 | 2004 |
| Biochemical identification of a linear cholesterol-binding domain within Alzheimer’s β amyloid peptide C Di Scala, N Yahi, C Lelièvre, N Garmy, H Chahinian, J Fantini ACS chemical neuroscience 4 (3), 509-517, 2013 | 82 | 2013 |
| Inactivation of pancreatic and gastric lipases by THL and C12: 0-TNB: a kinetic study with emulsified tributyrin Y Gargouri, H Chahinian, H Moreau, S Ransac, R Verger Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1085 (3 …, 1991 | 82 | 1991 |
| Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination? N Yahi, H Chahinian, J Fantini Journal of Infection 83 (5), 607-635, 2021 | 75 | 2021 |
| Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases H Chahinian, YB Ali, A Abousalham, S Petry, L Mandrich, G Manco, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2005 | 74 | 2005 |
| Physiology of gastrointestinal lipolysis and therapeutical use of lipases and digestive lipase inhibitors H Lengsfeld, G Beaumier‐Gallon, H Chahinian, A De Caro, R Verger, ... Lipases and phospholipases in drug development: from biochemistry to …, 2004 | 72 | 2004 |
| How gastric lipase, an interfacial enzyme with a Ser-His-Asp catalytic triad, acts optimally at acidic pH H Chahinian, T Snabe, C Attias, P Fojan, SB Petersen, F Carrière Biochemistry 45 (3), 993-1001, 2006 | 70 | 2006 |
