Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor HR Kast, B Goodwin, PT Tarr, SA Jones, AM Anisfeld, CM Stoltz, ... Journal of Biological Chemistry 277 (4), 2908-2915, 2002 | 1132 | 2002 |
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes BA Laffitte, JJ Repa, SB Joseph, DC Wilpitz, HR Kast, DJ Mangelsdorf, ... Proceedings of the National Academy of Sciences 98 (2), 507-512, 2001 | 857 | 2001 |
BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis PA Edwards, HR Kast, AM Anisfeld Journal of lipid research 43 (1), 2-12, 2002 | 473 | 2002 |
Regulation of gene expression by SREBP and SCAP PA Edwards, D Tabor, HR Kast, A Venkateswaran Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2000 | 452 | 2000 |
A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR M Downes, MA Verdecia, AJ Roecker, R Hughes, JB Hogenesch, ... Molecular cell 11 (4), 1079-1092, 2003 | 437 | 2003 |
Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids HR Kast, CM Nguyen, CJ Sinal, SA Jones, BA Laffitte, K Reue, ... Molecular endocrinology 15 (10), 1720-1728, 2001 | 413 | 2001 |
Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation Y Zhang, HR Kast-Woelbern, PA Edwards Journal of Biological Chemistry 278 (1), 104-110, 2003 | 370 | 2003 |
Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor BA Laffitte, HR Kast, CM Nguyen, AM Zavacki, DD Moore, PA Edwards Journal of Biological Chemistry 275 (14), 10638-10647, 2000 | 323 | 2000 |
Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors PA Mak, HR Kast-Woelbern, AM Anisfeld, PA Edwards Journal of lipid research 43 (12), 2037-2041, 2002 | 169 | 2002 |
Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding … HR Kast-Woelbern, SL Dana, RM Cesario, L Sun, LY de Grandpre, ... Journal of Biological Chemistry 279 (23), 23908-23915, 2004 | 136 | 2004 |
Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor AM Anisfeld, HR Kast-Woelbern, ME Meyer, SA Jones, Y Zhang, ... Journal of Biological Chemistry 278 (22), 20420-20428, 2003 | 107 | 2003 |
CTP: phosphocholine cytidylyltransferase, a new sterol-and SREBP-responsive gene HR Kast, CM Nguyen, AM Anisfeld, J Ericsson, PA Edwards Journal of lipid research 42 (8), 1266-1272, 2001 | 70 | 2001 |
A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids DM Shih, HR Kast-Woelbern, J Wong, YR Xia, PA Edwards, AJ Lusis Journal of lipid research 47 (2), 384-392, 2006 | 55 | 2006 |
α-crystallin is a target gene of the farnesoid X-activated receptor in human livers FY Lee, HR Kast-Woelbern, J Chang, G Luo, SA Jones, MC Fishbein, ... Journal of Biological Chemistry 280 (36), 31792-31800, 2005 | 47 | 2005 |
Activation of the nuclear receptor FXR induces fibrinogen expression: a new role for bile acid signaling AM Anisfeld, HR Kast-Woelbern, H Lee, Y Zhang, FY Lee, PA Edwards Journal of lipid research 46 (3), 458-468, 2005 | 45 | 2005 |
A novel method of screening combinations of angiostatics identifies bevacizumab and temsirolimus as synergistic inhibitors of glioma-induced angiogenesis MI Dorrell, HR Kast-Woelbern, RT Botts, SA Bravo, JR Tremblay, S Giles, ... PloS one 16 (6), e0252233, 2021 | 5 | 2021 |
Rosiglitazone induction of INSIG-1 in white adipose tissue reveals a novel interplay of PPARg and SREBP in the regulation of adipogenesis HR Kast-Woelbern, SL Dana, RM Cesario, L Sun, LY De Grandpre, ... J Biol Chem 279, 23908-23915, 2004 | 2 | 2004 |
Cholesterol Signaling PA Edwards, HR Kast-Woelbern, MA Kennedy Handbook of cell signaling, 287-290, 2003 | 2 | 2003 |
Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor AM ANISFELD, HR KAST-WOELBERN, ME MEYER, SA JONES, ... The Journal of biological chemistry 284 (11), 7404-7404, 2009 | | 2009 |
The farnesoid-X-activated receptor and its role in lipid metabolism HR Kast University of California, Los Angeles, 2001 | | 2001 |