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Scott D. Gorman
Scott D. Gorman
Scientist I, Arrakis Therapeutics
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Cited by
Cited by
Year
Phase separation mediates NUP98 fusion oncoprotein leukemic transformation
B Chandra, NL Michmerhuizen, HK Shirnekhi, S Tripathi, BJ Pioso, ...
Cancer discovery 12 (4), 1152-1169, 2022
732022
Biophysical and computational methods to analyze amino acid interaction networks in proteins
KF O'Rourke, SD Gorman, DD Boehr
Computational and structural biotechnology journal 14, 245-251, 2016
632016
Assigning methyl resonances for protein solution-state NMR studies
SD Gorman, D Sahu, KF O'Rourke, DD Boehr
Methods 148, 88-99, 2018
252018
Engineering allostery into proteins
SD Gorman, RN D’Amico, DS Winston, DD Boehr
Protein Allostery in Drug Discovery, 359-384, 2019
142019
Defining the condensate landscape of fusion oncoproteins
S Tripathi, HK Shirnekhi, SD Gorman, B Chandra, DW Baggett, CG Park, ...
Nature communications 14 (1), 6008, 2023
122023
Different Solvent and Conformational Entropy Contributions to the Allosteric Activation and Inhibition Mechanisms of Yeast Chorismate Mutase
SD Gorman, DS Winston, D Sahu, D Boehr
92020
Energy and enzyme activity landscapes of yeast chorismate mutase at cellular concentrations of allosteric effectors
SD Gorman, DD Boehr
Biochemistry 58 (39), 4058-4069, 2019
82019
Conformational transitions in yeast chorismate mutase important for allosteric regulation as identified by nuclear magnetic resonance spectroscopy
DS Winston, SD Gorman, DD Boehr
Journal of Molecular Biology 434 (17), 167531, 2022
52022
AML-158 Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation
N Michmerhuizen, B Chandra, H Shirnekhi, S Tripathi, B Pioso, D Baggett, ...
Clinical Lymphoma Myeloma and Leukemia 22, S220, 2022
12022
Understanding condensate formation by fusion oncoprotein-derived intrinsically disordered regions
S Kinger, BJ Pioso, S Tripathi, AH Phillips, CG Park, S Maiti, SD Gorman, ...
Biophysical Journal 122 (3), 345a, 2023
2023
Track: Structure and Dynamics Perspectives on Enzyme Function Dynamics, ensembles, and solvent interactions: the complex energy landscape of chorismate mutase allostery
D Boehr, D Winston, S Gorman, E Nelson, D Sahu
PROTEIN SCIENCE 32, 2023
2023
Poster: AML-158 Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation
N Michmerhuizen, B Chandra, H Shirnekhi, S Tripathi, B Pioso, D Baggett, ...
Clinical Lymphoma, Myeloma and Leukemia 22, S129, 2022
2022
Understanding the mechanism of TCF3-HLF fusion oncoprotein-driven leukemogenesis
HK Shirnekhi, SD Gorman, NL Michmerhuizen, S Tripathi, A Medyukhina, ...
Biophysical Journal 121 (3), 356a, 2022
2022
Are fusion oncoproteins a source of disease-relevant, phase separation-prone protein regions?
SD Gorman, H Shirnekhi, R Somjee, S Tripathi, CG Park, AH Phillips, ...
Biophysical Journal 121 (3), 307a, 2022
2022
A Six-State Binding Model Gives Rise to Dynamic Activity and Energy Landscapes in Yeast Chorismate Mutase
SD Gorman, DS Winston, D Sahu, DD Boehr
Biophysical Journal 118 (3), 519a, 2020
2020
Insight into mechanisms of allosteric regulation and cooperativity from yeast chorismate mutase
S Gorman
2020
Translating Membrane Structure into Protein Localization and Function
SD Gorman
The Pennsylvania State University, 2020
2020
The Importance of Protein Structural Dynamics in the Allosteric Mechanism of Yeast Chorismate Mutase
S Gorman, D Sahu, D Boehr
PROTEIN SCIENCE 27, 86-86, 2018
2018
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Articles 1–18