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Shunqing Liang
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Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice
P Liu, SQ Liang, C Zheng, E Mintzer, YG Zhao, K Ponnienselvan, A Mir, ...
Nature communications 12 (1), 2121, 2021
1892021
New horizons in KRAS-mutant lung cancer: dawn after darkness
H Yang, SQ Liang, RA Schmid, RW Peng
Frontiers in oncology 9, 482949, 2019
1302019
A split prime editor with untethered reverse transcriptase and circular RNA template
B Liu, X Dong, H Cheng, C Zheng, Z Chen, TC Rodríguez, SQ Liang, ...
Nature Biotechnology 40 (9), 1388-1393, 2022
902022
Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer
SQ Liang, TM Marti, P Dorn, L Froment, SRR Hall, S Berezowska, ...
Cell death & disease 6 (7), e1824-e1824, 2015
902015
Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins
J Lee, H Mou, R Ibraheim, SQ Liang, P Liu, W Xue, EJ Sontheimer
Rna 25 (11), 1421-1431, 2019
882019
Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing
B Li, RS Manan, SQ Liang, A Gordon, A Jiang, A Varley, G Gao, R Langer, ...
Nature biotechnology 41 (10), 1410-1415, 2023
742023
A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver
C Zheng, SQ Liang, B Liu, P Liu, SY Kwan, SA Wolfe, W Xue
Molecular Therapy 30 (3), 1343-1351, 2022
592022
HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer
H Yang, SQ Liang, D Xu, Z Yang, TM Marti, Y Gao, GJ Kocher, H Zhao, ...
Oncogenesis 8 (9), 45, 2019
492019
mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer
SQ Liang, ED Bührer, S Berezowska, TM Marti, D Xu, L Froment, H Yang, ...
Oncogene 38 (5), 622-636, 2019
452019
Immune response of turbot (Scophthalmus maximus L.) to a broad spectrum vaccine candidate, recombinant glyceraldehyde-3-phosphate dehydrogenase of Edwardsiella tarda
S Liang, H Wu, B Liu, J Xiao, Q Wang, Y Zhang
Veterinary immunology and immunopathology 150 (3-4), 198-205, 2012
352012
Endoplasmic reticulum stress signaling as a therapeutic target in malignant pleural mesothelioma
D Xu, H Yang, Z Yang, S Berezowska, Y Gao, SQ Liang, TM Marti, ...
Cancers 11 (10), 1502, 2019
322019
CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma
D Xu, SQ Liang, H Yang, R Bruggmann, S Berezowska, Z Yang, TM Marti, ...
Molecular cancer therapeutics 19 (2), 661-672, 2020
312020
Secreted glyceraldehyde‐3‐phosphate dehydrogenase as a broad spectrum vaccine candidate against microbial infection in aquaculture
X Li, H Wu, M Zhang, S Liang, J Xiao, Q Wang, Q Liu, Y Zhang
Letters in applied microbiology 54 (1), 1-9, 2012
312012
Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma
D Xu, SQ Liang, H Yang, U Lüthi, C Riether, S Berezowska, TM Marti, ...
British journal of cancer 119 (1), 65-75, 2018
302018
Genome-wide detection of CRISPR editing in vivo using GUIDE-tag
SQ Liang, P Liu, JL Smith, E Mintzer, S Maitland, X Dong, Q Yang, J Lee, ...
Nature communications 13 (1), 437, 2022
292022
AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway
SQ Liang, CJ Walkey, AE Martinez, Q Su, ME Dickinson, D Wang, ...
Molecular Therapy 30 (1), 238-243, 2022
272022
Analysis of unexpected small cell lung cancer following surgery as the primary treatment
H Yang, J Xu, F Yao, S Liang, H Zhao
Journal of cancer research and clinical oncology 144, 2441-2447, 2018
202018
Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag
SQ Liang, P Liu, K Ponnienselvan, S Suresh, Z Chen, C Kramme, ...
Nature Methods 20 (6), 898-907, 2023
182023
CRISPR-mediated kinome editing prioritizes a synergistic combination therapy for FGFR1-amplified lung cancer
Z Yang, SQ Liang, H Yang, D Xu, R Bruggmann, Y Gao, H Deng, ...
Cancer research 81 (11), 3121-3133, 2021
132021
YAP1 withdrawal in hepatoblastoma drives therapeutic differentiation of tumor cells to functional hepatocyte‐like cells
JL Smith, TC Rodríguez, H Mou, SY Kwan, H Pratt, XO Zhang, Y Cao, ...
Hepatology 73 (3), 1011-1027, 2021
132021
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