A multistage tuberculosis vaccine that confers efficient protection before and after exposure C Aagaard, T Hoang, J Dietrich, PJ Cardona, A Izzo, G Dolganov, ... Nature medicine 17 (2), 189-194, 2011 | 643 | 2011 |
Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells T Lindenstrøm, EM Agger, KS Korsholm, PA Darrah, C Aagaard, ... The Journal of Immunology 182 (12), 8047-8055, 2009 | 470 | 2009 |
Exchanging ESAT6 with TB10. 4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy J Dietrich, C Aagaard, R Leah, AW Olsen, A Stryhn, TM Doherty, ... The Journal of Immunology 174 (10), 6332-6339, 2005 | 351 | 2005 |
Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6 JAM Langermans, TM Doherty, RAW Vervenne, T van der Laan, ... Vaccine 23 (21), 2740-2750, 2005 | 335 | 2005 |
Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements EM Agger, I Rosenkrands, J Hansen, K Brahimi, BS Vandahl, C Aagaard, ... PloS one 3 (9), e3116, 2008 | 332 | 2008 |
Prion protein of 106 residues creates an artificial transmission barrier for prion replication in transgenic mice S Supattapone, P Bosque, T Muramoto, H Wille, C Aagaard, D Peretz, ... Cell 96 (6), 869-878, 1999 | 267 | 1999 |
Hypoxic Response of Mycobacterium tuberculosis Studied by Metabolic Labeling and Proteome Analysis of Cellular and Extracellular Proteins I Rosenkrands, RA Slayden, J Crawford, C Aagaard, CE Barry III, ... Journal of bacteriology 184 (13), 3485-3491, 2002 | 252 | 2002 |
Protection and polyfunctional T cells induced by Ag85B-TB10. 4/IC31® against Mycobacterium tuberculosis is highly dependent on the antigen dose C Aagaard, TTKT Hoang, A Izzo, R Billeskov, JL Troudt, K Arnett, ... PloS one 4 (6), e5930, 2009 | 207 | 2009 |
Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and … NN Chegou, JS Sutherland, S Malherbe, AC Crampin, PLAM Corstjens, ... Thorax 71 (9), 785-794, 2016 | 167 | 2016 |
Vaccine-induced th17 cells are maintained long-term postvaccination as a distinct and phenotypically stable memory subset T Lindenstrøm, J Woodworth, J Dietrich, C Aagaard, P Andersen, ... Infection and immunity 80 (10), 3533-3544, 2012 | 148 | 2012 |
Archaeal introns: splicing, intercellular mobility and evolution J Lykke-Andersen, C Aagaard, M Semionenkov, RA Garrett Trends in biochemical sciences 22 (9), 326-331, 1997 | 135 | 1997 |
Optimizing Antigen Cocktails for Detection of Mycobacterium bovis in Herds with Different Prevalences of Bovine Tuberculosis: ESAT6-CFP10 Mixture Shows … C Aagaard, M Govaerts, V Meikle, AJ Vallecillo, JA Gutierrez-Pabello, ... Journal of Clinical Microbiology 44 (12), 4326-4335, 2006 | 134 | 2006 |
Improved serodetection of Mycobacterium bovis infection in badgers (Meles meles) using multiantigen test formats R Greenwald, J Esfandiari, S Lesellier, R Houghton, J Pollock, C Aagaard, ... Diagnostic microbiology and infectious disease 46 (3), 197-203, 2003 | 129 | 2003 |
Quality and vaccine efficacy of CD4+ T cell responses directed to dominant and subdominant epitopes in ESAT-6 from Mycobacterium tuberculosis CS Aagaard, TTKT Hoang, C Vingsbo-Lundberg, J Dietrich, P Andersen The Journal of Immunology 183 (4), 2659-2668, 2009 | 115 | 2009 |
Erythromycin binding is reduced in ribosomes with conformational alterations in the 23 S rRNA peptidyl transferase loop S Douthwaite, C Aagaard Journal of molecular biology 232 (3), 725-731, 1993 | 115 | 1993 |
TB vaccines: current status and future perspectives C Aagaard, J Dietrich, M Doherty, P Andersen Immunology and cell biology 87 (4), 279-286, 2009 | 109 | 2009 |
ESAT-6 (EsxA) and TB10. 4 (EsxH) based vaccines for pre-and post-exposure tuberculosis vaccination T Hoang, C Aagaard, J Dietrich, JP Cassidy, G Dolganov, GK Schoolnik, ... PloS one 8 (12), e80579, 2013 | 107 | 2013 |
Mapping Immune Reactivity toward Rv2653 and Rv2654: Two Novel Low-Molecular-Mass Antigens Found Specifically in the Mycobacterium tuberculosis Complex C Aagaard, I Brock, A Olsen, THM Ottenhoff, K Weldingh, P Andersen Journal of Infectious Diseases 189 (5), 812-819, 2004 | 105 | 2004 |
Self-assembly of recombinant prion protein of 106 residues IV Baskakov, C Aagaard, I Mehlhorn, H Wille, D Groth, MA Baldwin, ... Biochemistry 39 (10), 2792-2804, 2000 | 90 | 2000 |
Protective CD4 T cells targeting cryptic epitopes of Mycobacterium tuberculosis resist infection-driven terminal differentiation JS Woodworth, CS Aagaard, PR Hansen, JP Cassidy, EM Agger, ... The Journal of Immunology 192 (7), 3247-3258, 2014 | 86 | 2014 |