Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 M Tahiliani, KP Koh, Y Shen, WA Pastor, H Bandukwala, Y Brudno, ... Science 324 (5929), 930-935, 2009 | 6366 | 2009 |
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription WA Pastor, L Aravind, A Rao Nature reviews Molecular cell biology 14 (6), 341-356, 2013 | 950 | 2013 |
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells WA Pastor, UJ Pape, Y Huang, HR Henderson, R Lister, M Ko, ... Nature 473 (7347), 394-397, 2011 | 949 | 2011 |
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing Y Huang, WA Pastor, Y Shen, M Tahiliani, DR Liu, A Rao PloS one 5 (1), e8888, 2010 | 850 | 2010 |
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX M Ko, J An, HS Bandukwala, L Chavez, T Äijö, WA Pastor, MF Segal, H Li, ... Nature 497 (7447), 122-126, 2013 | 436 | 2013 |
Control of Foxp3 stability through modulation of TET activity X Yue, S Trifari, T Äijö, A Tsagaratou, WA Pastor, JA Zepeda-Martínez, ... Journal of Experimental Medicine 213 (3), 377-397, 2016 | 306 | 2016 |
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells Y Huang, L Chavez, X Chang, X Wang, WA Pastor, J Kang, ... Proceedings of the National Academy of Sciences 111 (4), 1361-1366, 2014 | 295 | 2014 |
Naive human pluripotent cells feature a methylation landscape devoid of blastocyst or germline memory WA Pastor, D Chen, W Liu, R Kim, A Sahakyan, A Lukianchikov, K Plath, ... Cell stem cell 18 (3), 323-329, 2016 | 272 | 2016 |
TET proteins and 5‐methylcytosine oxidation in hematological cancers M Ko, J An, WA Pastor, SB Koralov, K Rajewsky, A Rao Immunological reviews 263 (1), 6-21, 2015 | 229 | 2015 |
In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse M Morselli, WA Pastor, B Montanini, K Nee, R Ferrari, K Fu, G Bonora, ... Elife 4, e06205, 2015 | 173 | 2015 |
TFAP2C regulates transcription in human naive pluripotency by opening enhancers WA Pastor, W Liu, D Chen, J Ho, R Kim, TJ Hunt, A Lukianchikov, X Liu, ... Nature cell biology 20 (5), 553-564, 2018 | 166 | 2018 |
SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer Y Xue, B Meehan, Z Fu, XQD Wang, PO Fiset, R Rieker, C Levins, T Kong, ... Nature communications 10 (1), 557, 2019 | 152 | 2019 |
Reprogramming roadmap reveals route to human induced trophoblast stem cells X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ... Nature 586 (7827), 101-107, 2020 | 147 | 2020 |
Naive human embryonic stem cells can give rise to cells with a trophoblast-like transcriptome and methylome JK Cinkornpumin, SY Kwon, Y Guo, I Hossain, J Sirois, CS Russett, ... Stem cell reports 15 (1), 198-213, 2020 | 134 | 2020 |
TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells A Tsagaratou, E González-Avalos, S Rautio, JP Scott-Browne, S Togher, ... Nature immunology 18 (1), 45-53, 2017 | 130 | 2017 |
MORC1 represses transposable elements in the mouse male germline WA Pastor, H Stroud, K Nee, W Liu, D Pezic, S Manakov, SA Lee, ... Nature communications 5 (1), 5795, 2014 | 129 | 2014 |
Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis J Kang, M Lienhard, WA Pastor, A Chawla, M Novotny, A Tsagaratou, ... Proceedings of the National Academy of Sciences 112 (31), E4236-E4245, 2015 | 117 | 2015 |
MIWI2 and MILI have differential effects on piRNA biogenesis and DNA methylation SA Manakov, D Pezic, GK Marinov, WA Pastor, R Sachidanandam, ... Cell reports 12 (8), 1234-1243, 2015 | 112 | 2015 |
The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine Y Huang, WA Pastor, JA Zepeda-Martínez, A Rao Nature protocols 7 (10), 1897-1908, 2012 | 89 | 2012 |
Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling X Li, X Yue, WA Pastor, L Lin, R Georges, L Chavez, SM Evans, A Rao Proceedings of the National Academy of Sciences 113 (51), E8267-E8276, 2016 | 88 | 2016 |