The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress JR Morris, C Boutell, M Keppler, R Densham, D Weekes, A Alamshah, ... Nature 462 (7275), 886-890, 2009 | 529 | 2009 |
Herpes simplex virus type 1 immediate-early protein ICP0 and its isolated RING finger domain act as ubiquitin E3 ligases in vitro C Boutell, S Sadis, RD Everett Journal of virology 76 (2), 841-850, 2002 | 487 | 2002 |
Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2 E Meulmeester, MM Maurice, C Boutell, AFAS Teunisse, H Ovaa, ... Molecular cell 18 (5), 565-576, 2005 | 330 | 2005 |
Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2 E Meulmeester, MM Maurice, C Boutell, AFAS Teunisse, H Ovaa, ... Molecular cell 18 (5), 565-576, 2005 | 330 | 2005 |
Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement JB Parsons, S Frank, D Bhella, M Liang, MB Prentice, DP Mulvihill, ... Molecular cell 38 (2), 305-315, 2010 | 259* | 2010 |
Regulation of alphaherpesvirus infections by the ICP0 family of proteins C Boutell, RD Everett Journal of General Virology 94 (3), 465-481, 2013 | 235 | 2013 |
A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses CE Lilley, MS Chaurushiya, C Boutell, S Landry, J Suh, S Panier, ... The EMBO journal 29 (5), 943-955, 2010 | 212 | 2010 |
A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7 M Canning, C Boutell, J Parkinson, RD Everett Journal of Biological Chemistry 279 (37), 38160-38168, 2004 | 200 | 2004 |
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and ubiquitinates p53 C Boutell, RD Everett Journal of Biological Chemistry 278 (38), 36596-36602, 2003 | 195 | 2003 |
A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence C Boutell, D Cuchet-Lourenço, E Vanni, A Orr, M Glass, S McFarlane, ... PLoS pathogens 7 (9), e1002245, 2011 | 192 | 2011 |
Interplay between viruses and host sumoylation pathways RD Everett, C Boutell, BG Hale Nature Reviews Microbiology 11 (6), 400-411, 2013 | 187 | 2013 |
Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7 C Boutell, M Canning, A Orr, RD Everett Journal of virology 79 (19), 12342-12354, 2005 | 178 | 2005 |
Host and viral determinants of Mx2 antiretroviral activity I Busnadiego, M Kane, SJ Rihn, HF Preugschas, J Hughes, ... Journal of virology 88 (14), 7738-7752, 2014 | 171 | 2014 |
Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0 RD Everett, C Boutell, A Orr Journal of virology 78 (4), 1763-1774, 2004 | 165 | 2004 |
The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0 CE Lilley, MS Chaurushiya, C Boutell, RD Everett, MD Weitzman PLoS pathogens 7 (6), e1002084, 2011 | 157 | 2011 |
Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility JR Morris, L Pangon, C Boutell, T Katagiri, NH Keep, E Solomon Human molecular genetics 15 (4), 599-606, 2006 | 129 | 2006 |
PML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0 C Boutell, A Orr, RD Everett Journal of virology 77 (16), 8686-8694, 2003 | 128 | 2003 |
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes D Cuchet-Lourenço, C Boutell, V Lukashchuk, K Grant, A Sykes, J Murray, ... PLoS pathogens 7 (7), e1002123, 2011 | 117 | 2011 |
A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication SJ Griffiths, M Koegl, C Boutell, HL Zenner, CM Crump, F Pica, ... PLoS Pathogens 9 (8), e1003514, 2013 | 114 | 2013 |
Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain MS Chaurushiya, CE Lilley, A Aslanian, J Meisenhelder, DC Scott, ... Molecular cell 46 (1), 79-90, 2012 | 105 | 2012 |