| Antimalarial, antiproliferative, and antitumor activities of artemisinin-derived, chemically robust, trioxane dimers GH Posner, P Ploypradith, MH Parker, H O'dowd, SH Woo, J Northrop, ... Journal of medicinal chemistry 42 (21), 4275-4280, 1999 | 194 | 1999 |
| Antimalarial, antiproliferative, and antitumor activities of artemisinin-derived, chemically robust, trioxane dimers GH Posner, P Ploypradith, MH Parker, H O'dowd, SH Woo, J Northrop, ... Journal of medicinal chemistry 42 (21), 4275-4280, 1999 | 192 | 1999 |
| Antimalarial, antiproliferative, and antitumor activities of artemisinin-derived, chemically robust, trioxane dimers GH Posner, P Ploypradith, MH Parker, H O'Dowd, SH Woo, J Northrop, ... Journal of medicinal chemistry 42 (21), 4275-4280, 1999 | 192 | 1999 |
| 2-Amino-3, 4-dihydroquinazolines as inhibitors of BACE-1 (β-site APP cleaving enzyme): use of structure based design to convert a micromolar hit into a nanomolar lead EW Baxter, KA Conway, L Kennis, F Bischoff, MH Mercken, HL De Winter, ... Journal of medicinal chemistry 50 (18), 4261-4264, 2007 | 184 | 2007 |
| Orally active, hydrolytically stable, semisynthetic, antimalarial trioxanes in the artemisinin family GH Posner, MH Parker, J Northrop, JS Elias, P Ploypradith, S Xie, ... Journal of medicinal chemistry 42 (2), 300-304, 1999 | 137 | 1999 |
| The role of sulfamide derivatives in medicinal chemistry: a patent review (2006–2008) AB Reitz, GR Smith, MH Parker Expert opinion on therapeutic patents 19 (10), 1449-1453, 2009 | 92 | 2009 |
| Antimalarial simplified 3-aryltrioxanes: synthesis and preclinical efficacy/toxicity testing in rodents GH Posner, HB Jeon, MH Parker, M Krasavin, IH Paik, TA Shapiro Journal of medicinal chemistry 44 (19), 3054-3058, 2001 | 72 | 2001 |
| Direct conversion of Pyranose anomeric OH→ F→ R in the Artemisinin Family of Antimalarial Trioxanes SH Woo, MH Parker, P Ploypradith, J Northrop, GH Posner Tetrahedron letters 39 (12), 1533-1536, 1998 | 67 | 1998 |
| Synthesis of (−)-5, 8-Dihydroxy-3R-methyl-2R-(dipropylamino)-1, 2, 3, 4-tetrahydronaphthalene: An Inhibitor of β-Amyloid 1–42 Aggregation MH Parker, R Chen, KA Conway, DHS Lee, C Luo, RE Boyd, SO Nortey, ... Bioorganic & medicinal chemistry 10 (11), 3565-3569, 2002 | 41 | 2002 |
| Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo [b] thien-3-yl) methyl) sulfamide (JNJ-26990990) into human clinical studies MH Parker, VL Smith-Swintosky, DF McComsey, Y Huang, D Brenneman, ... Journal of medicinal chemistry 52 (23), 7528-7536, 2009 | 38 | 2009 |
| Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads Y Huang, ED Strobel, CY Ho, CH Reynolds, KA Conway, JA Piesvaux, ... Bioorganic & medicinal chemistry letters 20 (10), 3158-3160, 2010 | 36 | 2010 |
| Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy T Lu, C Schubert, MD Cummings, G Bignan, PJ Connolly, K Smans, ... Bioorganic & medicinal chemistry letters 28 (12), 2159-2164, 2018 | 33 | 2018 |
| CO-THERAPY FOR THE TREATMENT OF EPILEPSY AND RELATED DISORDERS VL Smith-swintosky, MH Parker, AB Reitz, BE Maryanoff, DF Mccomsey EP Patent 2,026,790, 2009 | 32* | 2009 |
| NOVEL BENZO-FUSED HETEROARYL SULFAMIDE DERIVATIVES USEFUL AS ANTICONVULSANT AGENTS MH Parker, AB Reitz, BE Maryanoff EP Patent 1,794,143, 2008 | 32 | 2008 |
| Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents MH Parker, AB Reitz, BE Maryanoff US Patent App. 11/209,122, 2005 | 32 | 2005 |
| Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders DF McComsey, MH Parker, AB Reitz, BE Maryanoff US Patent App. 11/154,386, 2005 | 32 | 2005 |
| Synthesis of Several Naturally Occurring Polyhalogenated Monoterpenes of the Halomon Class1 ME Jung, MH Parker The Journal of Organic Chemistry 62 (21), 7094-7095, 1997 | 31 | 1997 |
| Co-therapy for the treatment of epilepsy and related disorders VL Smith-Swintosky, DF Mccomsey, MH Parker, AB Reitz, BE Maryanoff US Patent 8,853,263, 2014 | 26 | 2014 |
| Co-therapy for the treatment of epilepsy and related disorders VL Smith-Swintosky, DF Mccomsey, MH Parker, AB Reitz, BE Maryanoff US Patent 8,853,263, 2014 | 26 | 2014 |
| Novel, Broad-Spectrum Anticonvulsants Containing a Sulfamide Group: Pharmacological Properties of (S)-N-[(6-Chloro-2, 3-dihydrobenzo [1, 4] dioxin-2-yl) methyl] sulfamide (JNJ … DF McComsey, VL Smith-Swintosky, MH Parker, DE Brenneman, ... Journal of medicinal chemistry 56 (22), 9019-9030, 2013 | 26 | 2013 |
