The molecular principles governing the activity and functional diversity of AAA+ proteins C Puchades, CR Sandate, GC Lander Nature Reviews Molecular Cell Biology 21 (1), 43-58, 2020 | 176 | 2020 |
Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1 AK Michael, JL Fribourgh, Y Chelliah, CR Sandate, GL Hura, ... Proceedings of the National Academy of Sciences 114 (7), 1560-1565, 2017 | 100 | 2017 |
Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity A Kriebs, SD Jordan, E Soto, E Henriksson, CR Sandate, ME Vaughan, ... Proceedings of the National Academy of Sciences 114 (33), 8776-8781, 2017 | 89 | 2017 |
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK: BMAL1 to control circadian timing JL Fribourgh, A Srivastava, CR Sandate, AK Michael, PL Hsu, C Rakers, ... Elife 9, e55275, 2020 | 57 | 2020 |
An allosteric network in spastin couples multiple activities required for microtubule severing CR Sandate, A Szyk, EA Zehr, GC Lander, A Roll-Mecak Nature structural & molecular biology 26 (8), 671-678, 2019 | 46 | 2019 |
Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking S Militi, ES Maywood, CR Sandate, JE Chesham, AR Barnard, ... Proceedings of the National Academy of Sciences 113 (10), 2756-2761, 2016 | 26 | 2016 |
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability JM Tsai, JD Aguirre, YD Li, J Brown, V Focht, L Kater, G Kempf, ... Molecular Cell 83 (15), 2753-2767. e10, 2023 | 14 | 2023 |
Coupling of distant ATPase domains in the circadian clock protein KaiC JA Swan, CR Sandate, AG Chavan, AM Freeberg, D Etwaru, DC Ernst, ... Nature structural & molecular biology 29 (8), 759-766, 2022 | 6 | 2022 |
Author Correction: An allosteric network in spastin couples multiple activities required for microtubule severing CR Sandate, A Szyk, EA Zehr, GC Lander, A Roll-Mecak Nature structural & molecular biology 27 (4), 400-400, 2020 | 3 | 2020 |
Protein dynamics regulate distinct biochemical properties of cryptochromes in mammalian circadian rhythms JL Fribourgh, A Srivastava, CR Sandate, AK Michael, PL Hsu, C Rakers, ... BioRxiv, 740464, 2019 | 2 | 2019 |
Hidden conformations differentiate day and night in a circadian pacemaker JA Swan, CR Sandate, AG Chavan, AM Freeberg, D Etwaru, DC Ernst, ... bioRxiv, 2021.09. 14.460370, 2021 | 1 | 2021 |
Structural insights into viral hijacking of p53 by E6 and E6AP CR Sandate, D Chakraborty, L Kater, G Kempf, NH Thoma bioRxiv, 2023.11. 01.565136, 2023 | | 2023 |
A C2-symmetric state in the AAA+ KaiC hexamer coordinates structural and functional modes within a molecular clock AM Freeberg, JA Swan, C Sandate, AG Chavan, D Ernst, D Etwaru, ... Biophysical Journal 121 (3), 42a-43a, 2022 | | 2022 |
Closing the negative feedback loop: a tandem ATPase keeps circadian time by coupling distant enzymatic activities JA Swan, CR Sandate, AM Freeberg, JC Heisler, DL Etwaru, C Sancar, ... Biophysical Journal 121 (3), 335a, 2022 | | 2022 |
How CRY Regulates the Clock: Structural Studies of a Dynamic Mammalian Circadian Complex C Sandate, J Fribourgh, A Michael, A Srivastava, G Hura, ... Acta Crystallographica Section A: Foundations and Advances 76, a122-a122, 2020 | | 2020 |
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK: BMAL1 JL Fribourgh, A Srivastava, CR Sandate | | 2020 |
Frozen in Time-How Phosphorylation Induces Conformational Rearrangement in the Circadian AAA+ ATPase KaiC CR Sandate, JA Swan, CL Partch, GC Lander Biophysical Journal 118 (3), 37a, 2020 | | 2020 |
Clocks and Motors: Cryo-EM Studies of AAA+ ATPases and Circadian Oscillators CR Sandate The Scripps Research Institute, 2020 | | 2020 |