Pan-cancer analysis of whole genomes I The, TPCA of Whole, Genomes Consortium Nature 578 (7793), 82, 2020 | 1484 | 2020 |
Expanded encyclopaedias of DNA elements in the human and mouse genomes JE Moore, MJ Purcaro, T Kawli, CA Davis, A Dobin, R Kaul, J Halow, ... Nature 583 (7818), 699-710, 2020 | 1136 | 2020 |
Multi-platform discovery of haplotype-resolved structural variation in human genomes MJP Chaisson, AD Sanders, X Zhao, A Malhotra, D Porubsky, T Rausch, ... Nature communications 10 (1), 1-16, 2019 | 743 | 2019 |
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ... Nature 578 (7793), 102-111, 2020 | 497 | 2020 |
Haplotype-resolved diverse human genomes and integrated analysis of structural variation P Ebert, PA Audano, Q Zhu, B Rodriguez-Martin, D Porubsky, MJ Bonder, ... Science, 2021 | 415 | 2021 |
High coverage whole genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios M Byrska-Bishop, US Evani, X Zhao, AO Basile, HJ Abel, AA Regier, ... bioRxiv, 2021 | 408 | 2021 |
Insights into genetics, human biology and disease gleaned from family based genomic studies JE Posey, AH O’Donnell-Luria, JX Chong, T Harel, SN Jhangiani, ... Genetics in Medicine 21 (4), 798-812, 2019 | 185 | 2019 |
Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences S Kumar, J Warrell, S Li, PD McGillivray, W Meyerson, L Salichos, ... Cell, 2020 | 114 | 2020 |
Reliability of Whole-Exome Sequencing for Assessing Intratumor Genetic Heterogeneity CH Weiwei Shi, Charlotte K.Y. Ng, Raymond S. Lim,Tingting Jiang, Sushant ... Cell Reports 25, 1446-1457, 2018 | 94 | 2018 |
Identifying allosteric hotspots with dynamics: Application to inter-and intra-species conservation D Clarke, A Sethi, S Li, S Kumar, RWF Chang, J Chen, M Gerstein Structure 24 (5), 826-837, 2016 | 56 | 2016 |
Centers for Mendelian Genomics: A decade of facilitating gene discovery SM Baxter, JE Posey, NJ Lake, N Sobreira, JX Chong, S Buyske, EE Blue, ... Genetics in Medicine, 2022 | 45 | 2022 |
Network analysis as a grand unifier in biomedical data science P McGillivray, D Clarke, W Meyerson, J Zhang, D Lee, M Gu, S Kumar, ... Annual Review of Biomedical Data Science 1, 153-180, 2018 | 43 | 2018 |
FAVOR: functional annotation of variants online resource and annotator for variation across the human genome H Zhou, T Arapoglou, X Li, Z Li, X Zheng, J Moore, A Asok, S Kumar, ... Nucleic Acids Research 51 (D1), D1300-D1311, 2023 | 40 | 2023 |
Germline determinants of the somatic mutation landscape in 2,642 cancer genomes SM Waszak, G Tiao, B Zhu, T Rausch, F Muyas, B Rodríguez-Martín, ... bioRxiv, 2017 | 34 | 2017 |
Leveraging protein dynamics to identify cancer mutational hotspots using 3D structures S Kumar, D Clarke, MB Gerstein Proceedings of the National Academy of Sciences 116 (38), 18962-18970, 2019 | 31 | 2019 |
SVFX: a machine-learning framework to quantify the pathogenicity of structural variants S Kumar, A Harmanci, J Vytheeswaran, MB Gerstein | 26 | 2019 |
Atomistic simulations reveal structural disorder in the RAP74-FCP1 complex C Wostenberg, S Kumar, WG Noid, SA Showalter The Journal of Physical Chemistry B 115 (46), 13731-13739, 2011 | 24 | 2011 |
Role of ordered proteins in the folding-upon-binding of intrinsically disordered proteins CW Lawrence, S Kumar, WG Noid, SA Showalter The journal of physical chemistry letters 5 (5), 833-838, 2014 | 23 | 2014 |
Localized structural frustration for evaluating the impact of sequence variants S Kumar, D Clarke, M Gerstein Nucleic acids research 44 (21), gkw927, 2013 | 19 | 2013 |
Cancer genomics: Less is more in the hunt for driver mutations S Kumar, M Gerstein Nature 547 (7661), 40-41, 2017 | 18 | 2017 |