p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion A Helman, A Klochendler, N Azazmeh, Y Gabai, E Horwitz, S Anzi, ... Nature medicine 22 (4), 412-420, 2016 | 311 | 2016 |
Circadian entrainment triggers maturation of human in vitro islets JR Alvarez-Dominguez, J Donaghey, N Rasouli, JHR Kenty, A Helman, ... Cell stem cell 26 (1), 108-122. e10, 2020 | 143 | 2020 |
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila L Ajuria, C Nieva, C Winkler, D Kuo, N Samper, MJ Andreu, A Helman, ... Development 138 (5), 915-924, 2011 | 120 | 2011 |
A nutrient-sensing transition at birth triggers glucose-responsive insulin secretion A Helman, AL Cangelosi, JC Davis, Q Pham, A Rothman, AL Faust, ... Cell metabolism 31 (5), 1004-1016. e5, 2020 | 102 | 2020 |
Inhibition of mTOR signaling enhances maturation of cardiomyocytes derived from human-induced pluripotent stem cells via p53-induced quiescence JC Garbern, A Helman, R Sereda, M Sarikhani, A Ahmed, GO Escalante, ... Circulation 141 (4), 285-300, 2020 | 94 | 2020 |
Glucose response by stem cell-derived β cells in vitro is inhibited by a bottleneck in glycolysis JC Davis, TC Alves, A Helman, JC Chen, JH Kenty, RL Cardone, DR Liu, ... Cell reports 31 (6), 2020 | 81 | 2020 |
The genetic program of pancreatic β-cell replication in vivo A Klochendler, I Caspi, N Corem, M Moran, O Friedlich, S Elgavish, ... Diabetes 65 (7), 2081-2093, 2016 | 78 | 2016 |
Effects of ageing and senescence on pancreatic β‐cell function A Helman, D Avrahami, A Klochendler, B Glaser, KH Kaestner, ... Diabetes, Obesity and Metabolism 18, 58-62, 2016 | 70 | 2016 |
Multiple RTK pathways downregulate Groucho-mediated repression in Drosophila embryogenesis E Cinnamon, A Helman, R Ben-Haroush Schyr, A Orian, G Jiménez, ... Oxford University Press for The Company of Biologists Limited 135 (5), 829-837, 2008 | 61 | 2008 |
A stem cell approach to cure type 1 diabetes A Helman, DA Melton Cold Spring Harbor Perspectives in Biology 13 (1), a035741, 2021 | 52 | 2021 |
Heparanase improves mouse embryo implantation A Revel, A Helman, M Koler, A Shushan, O Goldshmidt, E Zcharia, ... Fertility and sterility 83 (3), 580-586, 2005 | 45 | 2005 |
Postnatal exocrine pancreas growth by cellular hypertrophy correlates with a shorter lifespan in mammals S Anzi, M Stolovich-Rain, A Klochendler, O Fridlich, A Helman, ... Developmental cell 45 (6), 726-737. e3, 2018 | 42 | 2018 |
Capicua integrates input from two maternal systems in Drosophila terminal patterning E Cinnamon, D Gur‐Wahnon, A Helman, D St Johnston, G Jiménez, ... The EMBO journal 23 (23), 4571-4582, 2004 | 39 | 2004 |
RTK signaling modulates the Dorsal gradient A Helman, B Lim, MJ Andreu, Y Kim, T Shestkin, H Lu, G Jiménez, ... Development 139 (16), 3032-3039, 2012 | 31 | 2012 |
Phosphorylation of Groucho mediates RTK feedback inhibition and prolonged pathway target gene expression A Helman, E Cinnamon, S Mezuman, Z Hayouka, T Von Ohlen, A Orian, ... Current biology 21 (13), 1102-1110, 2011 | 27 | 2011 |
Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine AL Cangelosi, AM Puszynska, JM Roberts, A Armani, TP Nguyen, ... Science 377 (6601), 47-56, 2022 | 23 | 2022 |
Dynamics of Senescent Cell Formation and Retention Revealed by p14ARF Induction in the Epidermis R Tokarsky-Amiel, N Azazmeh, A Helman, Y Stein, A Hassan, A Maly, ... Cancer research 73 (9), 2829-2839, 2013 | 21 | 2013 |
Novel interplay between JNK and Egfr signaling in Drosophila dorsal closure T Kushnir, S Mezuman, S Bar-Cohen, R Lange, Z Paroush, A Helman PLoS genetics 13 (6), e1006860, 2017 | 15 | 2017 |
Live Cell Monitoring and Enrichment of Stem Cell‐Derived β Cells Using Intracellular Zinc Content as a Population Marker JC Davis, A Helman, J Rivera‐Feliciano, CM Langston, EN Engquist, ... Current protocols in stem cell biology 51 (1), e99, 2019 | 14 | 2019 |
An exercise-induced metabolic shield in distant organs blocks cancer progression and metastatic dissemination D Sheinboim, S Parikh, P Manich, I Markus, S Dahan, R Parikh, E Stubbs, ... Cancer Research 82 (22), 4164-4178, 2022 | 13 | 2022 |