| Lipopeptides from Bacillus and Paenibacillus spp.: a gold mine of antibiotic candidates SA Cochrane, JC Vederas Medicinal research reviews 36 (1), 4-31, 2016 | 451 | 2016 |
| Antimicrobial lipopeptide tridecaptin A1 selectively binds to Gram-negative lipid II SA Cochrane, B Findlay, A Bakhtiary, JZ Acedo, EM Rodriguez-Lopez, ... Proceedings of the National Academy of Sciences 113 (41), 11561-11566, 2016 | 131 | 2016 |
| Solid supported chemical syntheses of both components of the lantibiotic lacticin 3147 W Liu, ASH Chan, H Liu, SA Cochrane, JC Vederas Journal of the American Chemical Society 133 (36), 14216-14219, 2011 | 107 | 2011 |
| Synthesis and Structure–Activity Relationship Studies of N-Terminal Analogues of the Antimicrobial Peptide Tridecaptin A1 SA Cochrane, CT Lohans, JR Brandelli, G Mulvey, GD Armstrong, ... Journal of medicinal chemistry 57 (3), 1127-1131, 2014 | 72 | 2014 |
| Biochemical, Structural, and Genetic Characterization of Tridecaptin A1, an Antagonist of Campylobacter jejuni CT Lohans, MJ van Belkum, SA Cochrane, Z Huang, CS Sit, LM McMullen, ... ChemBioChem 15 (2), 243-249, 2014 | 71 | 2014 |
| Structures of DPAGT1 explain glycosylation disease mechanisms and advance TB antibiotic design YY Dong, H Wang, ACW Pike, SA Cochrane, S Hamedzadeh, ... Cell 175 (4), 1045-1058. e16, 2018 | 66 | 2018 |
| Insights into the mechanism of action of the two-peptide lantibiotic lacticin 3147 A Bakhtiary, SA Cochrane, P Mercier, RT McKay, M Miskolzie, CS Sit, ... Journal of the American Chemical Society 139 (49), 17803-17810, 2017 | 55 | 2017 |
| Breaking down the cell wall: Strategies for antibiotic discovery targeting bacterial transpeptidases SA Cochrane, CT Lohans European journal of medicinal chemistry 194, 112262, 2020 | 51 | 2020 |
| Studies on tridecaptin B 1, a lipopeptide with activity against multidrug resistant Gram-negative bacteria SA Cochrane, CT Lohans, MJ van Belkum, MA Bels, JC Vederas Organic & biomolecular chemistry 13 (21), 6073-6081, 2015 | 48 | 2015 |
| Synthesis of tridecaptin–antibiotic conjugates with in vivo activity against gram-negative bacteria SA Cochrane, X Li, S He, M Yu, M Wu, JC Vederas Journal of Medicinal Chemistry 58 (24), 9779-9785, 2015 | 46 | 2015 |
| Unacylated tridecaptin A1 acts as an effective sensitiser of Gram-negative bacteria to other antibiotics SA Cochrane, JC Vederas International journal of antimicrobial agents 44 (6), 493-499, 2014 | 40 | 2014 |
| Molecular cloning and characterization of drimenol synthase from valerian plant (Valeriana officinalis) M Kwon, SA Cochrane, JC Vederas, DK Ro FEBS letters 588 (24), 4597-4603, 2014 | 31 | 2014 |
| Key Residues in Octyl‐Tridecaptin A1 Analogues Linked to Stable Secondary Structures in the Membrane SA Cochrane, B Findlay, JC Vederas, ES Ratemi ChemBioChem 15 (9), 1295-1299, 2014 | 31 | 2014 |
| Investigation of the ring-closing metathesis of peptides in water SA Cochrane, Z Huang, JC Vederas Organic & biomolecular chemistry 11 (4), 630-639, 2013 | 31 | 2013 |
| Dissecting the binding interactions of teixobactin with the bacterial cell‐wall precursor lipid II S Chiorean, I Antwi, DW Carney, I Kotsogianni, AM Giltrap, FM Alexander, ... ChemBioChem 21 (6), 789-792, 2020 | 26 | 2020 |
| Binding studies reveal phospholipid specificity and its role in the calcium-dependent mechanism of action of daptomycin I Kotsogianni, TM Wood, FM Alexander, SA Cochrane, NI Martin ACS Infectious Diseases 7 (9), 2612-2619, 2021 | 25 | 2021 |
| Total Synthesis and Stereochemical Assignment of the Antimicrobial Lipopeptide Cerexin A1 SA Cochrane, RR Surgenor, KMW Khey, JC Vederas Organic letters 17 (21), 5428-5431, 2015 | 21 | 2015 |
| Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and in vivo efficacy K Al Ayed, RD Ballantine, M Hoekstra, SJ Bann, CMJ Wesseling, ... Chemical Science 13 (12), 3563-3570, 2022 | 20 | 2022 |
| Rational design of new cyclic analogues of the antimicrobial lipopeptide tridecaptin A 1 RD Ballantine, YX Li, PY Qian, SA Cochrane Chemical Communications 54 (75), 10634-10637, 2018 | 20 | 2018 |
| Tridecaptin-inspired antimicrobial peptides with activity against multidrug-resistant Gram-negative bacteria RD Ballantine, CE McCallion, E Nassour, S Tokajian, SA Cochrane MedChemComm 10 (3), 484-487, 2019 | 19 | 2019 |
Christopher LohansAssistant Professor, Queen's UniversityVerified email at queensu.ca
