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Diana Azzam, PhD
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Year
Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
MC Boelens, TJ Wu, BY Nabet, B Xu, Y Qiu, T Yoon, DJ Azzam, ...
Cell 159 (3), 499-513, 2014
8042014
VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2
D Zhao, C Pan, J Sun, C Gilbert, K Drews-Elger, DJ Azzam, M Picon-Ruiz, ...
Oncogene 34 (24), 3107-3119, 2015
2722015
Interactions between adipocytes and breast cancer cells stimulate cytokine production and drive Src/Sox2/miR-302b–mediated malignant progression
M Picon-Ruiz, C Pan, K Drews-Elger, K Jang, AH Besser, D Zhao, ...
Cancer research 76 (2), 491-504, 2016
1742016
Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer
AE Witt, CW Lee, TI Lee, DJ Azzam, B Wang, C Caslini, F Petrocca, ...
Oncogene 36 (12), 1707-1720, 2017
1582017
Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ‐secretase inhibitor drug responses
DJ Azzam, D Zhao, J Sun, AJ Minn, P Ranganathan, K Drews‐Elger, ...
EMBO molecular medicine 5 (10), 1502-1522, 2013
842013
Combined Src and ER blockade impairs human breast cancer proliferation in vitro and in vivo
Y Chen, EA Alvarez, D Azzam, SA Wander, N Guggisberg, M Jordą, Z Ju, ...
Breast cancer research and treatment 128, 69-78, 2011
682011
Dual Src and MEK inhibition decreases ovarian cancer growth and targets tumor initiating stem-like cells
F Simpkins, K Jang, H Yoon, KE Hew, M Kim, DJ Azzam, J Sun, D Zhao, ...
Clinical cancer research 24 (19), 4874-4886, 2018
662018
Src Inhibition with Saracatinib Reverses Fulvestrant Resistance in ER-Positive Ovarian Cancer Models In Vitro and In Vivo
F Simpkins, P Hevia-Paez, J Sun, W Ullmer, CA Gilbert, T Da Silva, ...
Clinical cancer research 18 (21), 5911-5923, 2012
612012
Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study
RT Swords, D Azzam, H Al-Ali, I Lohse, CH Volmar, JM Watts, A Perez, ...
Leukemia research 64, 34-41, 2018
532018
Imaging neuroinflammation with TSPO: A new perspective on the cellular sources and subcellular localization
TR Guilarte, AN Rodichkin, JL McGlothan, AMA De La Rocha, DJ Azzam
Pharmacology & therapeutics 234, 108048, 2022
422022
Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures
K Drews-Elger, JA Brinkman, P Miller, SH Shah, JC Harrell, TG Da Silva, ...
Breast cancer research and treatment 144, 503-517, 2014
412014
A new role for ERα: silencing via DNA methylation of basal, stem cell, and EMT genes
EA Ariazi, JC Taylor, MA Black, E Nicolas, MJ Slifker, DJ Azzam, J Boyd
Molecular Cancer Research 15 (2), 152-164, 2017
362017
DOT1L is a novel cancer stem cell target for triple-negative breast cancer
H Kurani, SF Razavipour, KB Harikumar, M Dunworth, AJ Ewald, A Nasir, ...
Clinical cancer research 28 (9), 1948-1965, 2022
242022
A novel interaction of translocator protein 18 kDa (TSPO) with NADPH oxidase in microglia
MK Loth, SR Guariglia, DB Re, J Perez, VN de Paiva, JL Dziedzic, ...
Molecular Neurobiology 57, 4467-4487, 2020
222020
Potential neuroprotective effects of continuous topiramate therapy in the developing brain
MA Mikati, R Daderian, M Zeinieh, AS Leonard, D Azzam, R Kurdi
Epilepsy & Behavior 20 (4), 597-601, 2011
202011
Programmed cell death in the lithium pilocarpine model: evidence for NMDA receptor and ceramide-mediated mechanisms
MA Mikati, E Rizk, S El Dada, M Zeinieh, R Kurdi, J El Hokayem, ...
Brain and Development 30 (8), 513-519, 2008
132008
Ovarian cancer treatment stratification using ex vivo drug sensitivity testing
I Lohse, DJ Azzam, H Al-Ali, CH Volmar, SP Brothers, TA Ince, ...
Anticancer research 39 (8), 4023-4030, 2019
112019
Surface translocator protein 18 kDa (TSPO) localization on immune cells upon stimulation with LPS and in ART-treated HIV+ subjects
LK Blevins, RB Crawford, DJ Azzam, TR Guilarte, NE Kaminski
Journal of leukocyte biology 110 (1), 123-140, 2021
62021
sVictor, BZ Wiemann, H. Ishwaran, PJ Ter Brugge, J. Jonkers, J. Slingerland
MC Boelens, TJ Wu, BY Nabet, B Xu, Y Qiu, T Yoon, DJ Azzam, ...
AJ Minn, Cell 159, 499, 2014
62014
The Translocator Protein (TSPO) Genetic Polymorphism A147T Is Associated with Worse Survival in Male Glioblastoma Patients
KM Troike, AM Acanda de la Rocha, TJ Alban, MM Grabowski, B Otvos, ...
Cancers 13 (18), 4525, 2021
42021
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