Beneficial role of Nrf2 in regulating NADPH generation and consumption KC Wu, JY Cui, CD Klaassen Toxicological Sciences 123 (2), 590-600, 2011 | 366 | 2011 |
Effect of graded Nrf2 activation on phase-I and-II drug metabolizing enzymes and transporters in mouse liver KC Wu, JY Cui, CD Klaassen PloS one 7 (7), e39006, 2012 | 165 | 2012 |
Nrf2 activation prevents cadmium-induced acute liver injury KC Wu, JJ Liu, CD Klaassen Toxicology and applied pharmacology 263 (1), 14-20, 2012 | 159 | 2012 |
NRF2 Protection against Liver Injury Produced by Various Hepatotoxicants J Liu, KC Wu, YF Lu, E Ekuase, CD Klaassen Oxidative medicine and cellular longevity 2013, 2013 | 154 | 2013 |
Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation KC Wu, J Liu, CD Klaassen Toxicology and applied pharmacology 262 (3), 321-329, 2012 | 146 | 2012 |
Genetic Activation of Nrf2 Protects against Fasting-Induced Oxidative Stress in Livers of Mice YKJ Zhang, KC Wu, CD Klaassen PloS one 8 (3), e59122, 2013 | 104 | 2013 |
Screening of Natural Compounds as Activators of the Keap1-Nrf2 Pathway KC Wu, PR McDonald, J Liu, CD Klaassen Planta medica 80 (01), 97-104, 2014 | 95 | 2014 |
Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet YKJ Zhang, KC Wu, J Liu, CD Klaassen Toxicology and applied pharmacology 264 (3), 305-314, 2012 | 95 | 2012 |
Oleanolic acid alters bile acid metabolism and produces cholestatic liver injury in mice J Liu, YF Lu, Y Zhang, KC Wu, F Fan, CD Klaassen Toxicology and applied pharmacology 272 (3), 816-824, 2013 | 49 | 2013 |
Implementation of a high-throughput screen for identifying small molecules to activate the Keap1-Nrf2-ARE pathway KC Wu, PR McDonald, JJ Liu, R Chaguturu, CD Klaassen Public Library of Science 7 (10), e44686, 2012 | 46 | 2012 |
Nrf2 protects against diquat-induced liver and lung injury KC Wu, Y Zhang, CD Klaassen Free Radical Research 46 (10), 1220-1229, 2012 | 46 | 2012 |
Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor J Rooney, K Oshida, N Vasani, B Vallanat, N Ryan, BN Chorley, X Wang, ... PloS one 13 (8), e0200004, 2018 | 45 | 2018 |
Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2 YF Lu, J Liu, KC Wu, CD Klaassen Toxicology letters 232 (1), 326-332, 2015 | 40 | 2015 |
Overexpression of Nrf2 Protects against Microcystin-Induced Hepatotoxicity in Mice YF Lu, J Liu, KC Wu, Q Qu, F Fan, CD Klaassen PLOS ONE 9 (3), e93013, 2014 | 38 | 2014 |
Structure-based design of potent, selective, and orally bioavailable VPS34 kinase inhibitors DX Hu, S Patel, H Chen, S Wang, ST Staben, YN Dimitrova, ... Journal of Medicinal Chemistry 65 (17), 11500-11512, 2021 | 14 | 2021 |
Dysregulation of the calcium handling protein, CCDC47, is associated with diabetic cardiomyopathy K Thapa, KC Wu, A Sarma, EM Grund, A Szeto, AJ Mendez, S Gesta, ... Cell & bioscience 8 (1), 1-13, 2018 | 14 | 2018 |
RNA-Seq provides new insights on the relative mRNA abundance of antioxidant components during mouse liver development KC Wu, JY Cui, J Liu, H Lu, X Zhong, CD Klaassen Free Radical Biology and Medicine 134, 335-342, 2019 | 10 | 2019 |
Tissue distribution, hormonal regulation, ontogeny, diurnal expression, and induction of mouse cystine transporters Slc3a1 and Slc7a9 KC Wu, SA Reisman, CD Klaassen Free radical research 54 (7), 525-534, 2020 | 6 | 2020 |
Assessment of skin toxicity in an in vitro reconstituted human epidermis model using deep learning F Hu, SF Santagostino, DM Danilenko, M Tseng, J Brumm, P Zehnder, ... The American Journal of Pathology 192 (4), 687-700, 2022 | 5 | 2022 |
Predicting Human Infection Risk: Do Rodent Host Resistance Models Add Value? KC Wu, Y Zhong, J Maher Toxicological Sciences 170 (2), 260-272, 2019 | 2 | 2019 |