| Senolytics improve physical function and increase lifespan in old age M Xu, T Pirtskhalava, JN Farr, BM Weigand, AK Palmer, MM Weivoda, ... Nature medicine 24 (8), 1246-1256, 2018 | 1652 | 2018 |
| Targeting cellular senescence prevents age-related bone loss in mice JN Farr, M Xu, MM Weivoda, DG Monroe, DG Fraser, JL Onken, ... Nature medicine 23 (9), 1072-1079, 2017 | 893 | 2017 |
| Fisetin is a senotherapeutic that extends health and lifespan MJ Yousefzadeh, YI Zhu, SJ McGowan, L Angelini, ... EBioMedicine 36, 18-28, 2018 | 668 | 2018 |
| JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age M Xu, T Tchkonia, H Ding, M Ogrodnik, ER Lubbers, T Pirtskhalava, ... Proceedings of the National Academy of Sciences 112 (46), E6301-E6310, 2015 | 666 | 2015 |
| Targeting senescent cells enhances adipogenesis and metabolic function in old age M Xu, AK Palmer, H Ding, MM Weivoda, T Pirtskhalava, TA White, A Sepe, ... elife 4, e12997, 2015 | 529 | 2015 |
| Targeting senescent cells alleviates obesity‐induced metabolic dysfunction AK Palmer, M Xu, YI Zhu, T Pirtskhalava, MM Weivoda, CM Hachfeld, ... Aging cell 18 (3), e12950, 2019 | 452 | 2019 |
| Obesity-induced cellular senescence drives anxiety and impairs neurogenesis M Ogrodnik, YI Zhu, LGP Langhi, T Tchkonia, P Krüger, E Fielder, ... Cell metabolism 29 (5), 1061-1077. e8, 2019 | 408 | 2019 |
| Cellular senescence in type 2 diabetes: a therapeutic opportunity AK Palmer, T Tchkonia, NK LeBrasseur, EN Chini, M Xu, JL Kirkland Diabetes 64 (7), 2289-2298, 2015 | 398 | 2015 |
| Transplanted senescent cells induce an osteoarthritis-like condition in mice M Xu, EW Bradley, MM Weivoda, SM Hwang, T Pirtskhalava, T Decklever, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017 | 335 | 2017 |
| Strategies for targeting senescent cells in human disease NS Gasek, GA Kuchel, JL Kirkland, M Xu Nature aging 1 (10), 870-879, 2021 | 232 | 2021 |
| 17α-Estradiol alleviates age-related metabolic and inflammatory dysfunction in male mice without inducing feminization MB Stout, FJ Steyn, MJ Jurczak, JPG Camporez, YI Zhu, JR Hawse, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017 | 108 | 2017 |
| Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity L Wang, B Wang, NS Gasek, Y Zhou, RL Cohn, DE Martin, W Zuo, ... Cell metabolism 34 (1), 75-89. e8, 2022 | 95 | 2022 |
| The heterogeneity of cellular senescence: insights at the single-cell level RL Cohn, NS Gasek, GA Kuchel, M Xu Trends in cell biology 33 (1), 9-17, 2023 | 83 | 2023 |
| An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo B Wang, L Wang, NS Gasek, Y Zhou, T Kim, C Guo, ER Jellison, ... Nature aging 1 (10), 962-973, 2021 | 79 | 2021 |
| Post‐translational modification of POU domain transcription factor Oct‐4 by SUMO‐1 Z Zhang, B Liao, M Xu, Y Jin The FASEB Journal 21 (12), 3042-3051, 2007 | 79 | 2007 |
| Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling LR Carpio, EW Bradley, ME McGee-Lawrence, MM Weivoda, DD Poston, ... Science signaling 9 (440), ra79-ra79, 2016 | 65 | 2016 |
| Perspective: Targeting the JAK/STAT pathway to fight age-related dysfunction M Xu, T Tchkonia, JL Kirkland Pharmacological Research 111, 152-154, 2016 | 63 | 2016 |
| Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia S Suvakov, H Cubro, WM White, YS Butler Tobah, TL Weissgerber, ... Biology of sex differences 10, 1-13, 2019 | 59 | 2019 |
| Transplanting cells from old but not young donors causes physical dysfunction in older recipients B Wang, Z Liu, VP Chen, L Wang, CL Inman, Y Zhou, C Guo, T Tchkonia, ... Aging cell 19 (3), e13106, 2020 | 53 | 2020 |
| Senolytics improve bone forming potential of bone marrow mesenchymal stem cells from aged mice Y Zhou, X Xin, L Wang, B Wang, L Chen, O Liu, DW Rowe, M Xu NPJ Regenerative medicine 6 (1), 34, 2021 | 44 | 2021 |
Mikołaj OgrodnikLudwig Boltzmann Research Group – Senescence and Healing of WoundsVerified email at trauma.lbg.ac.at
