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Tomoyo Sawada
Tomoyo Sawada
Research Scientist, Lieber Institute for Brain Development
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Year
Parkinson's disease–associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria
S Liu, T Sawada, S Lee, W Yu, G Silverio, P Alapatt, I Millan, A Shen, ...
PLoS genetics 8 (3), e1002537, 2012
4032012
Exome sequencing for bipolar disorder points to roles of de novo loss-of-function and protein-altering mutations
M Kataoka, N Matoba, T Sawada, AA Kazuno, M Ishiwata, K Fujii, ...
Molecular psychiatry 21 (7), 885-893, 2016
1182016
S-nitrosylation regulates mitochondrial quality control via activation of parkin
K Ozawa, AT Komatsubara, Y Nishimura, T Sawada, H Kawafune, ...
Scientific Reports 3 (1), 2202, 2013
942013
The Loss of PGAM5 Suppresses the Mitochondrial Degeneration Caused by Inactivation of PINK1 in Drosophila
Y Imai, T Kanao, T Sawada, Y Kobayashi, Y Moriwaki, Y Ishida, K Takeda, ...
PLoS genetics 6 (12), e1001229, 2010
902010
Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids
T Sawada, TE Chater, Y Sasagawa, M Yoshimura, N Fujimori-Tonou, ...
Molecular psychiatry 25 (11), 2695-2711, 2020
862020
Depression-like episodes in mice harboring mtDNA deletions in paraventricular thalamus
T Kasahara, A Takata, TM Kato, M Kubota-Sakashita, T Sawada, A Kakita, ...
Molecular psychiatry 21 (1), 39-48, 2016
842016
Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance
Z Wu, T Sawada, K Shiba, S Liu, T Kanao, R Takahashi, N Hattori, Y Imai, ...
Genes & development 27 (2), 157-162, 2013
532013
Parkin interacts with Klokin1 for mitochondrial import and maintenance of membrane potential
Y Kuroda, W Sako, S Goto, T Sawada, D Uchida, Y Izumi, T Takahashi, ...
Human molecular genetics 21 (5), 991-1003, 2012
402012
The Nitric Oxide-Cyclic GMP Pathway Regulates FoxO and Alters Dopaminergic Neuron Survival in Drosophila
T Kanao, T Sawada, SA Davies, H Ichinose, K Hasegawa, R Takahashi, ...
PloS one 7 (2), e30958, 2012
302012
Relation of the Glu298Asp polymorphism of the nitric oxide synthase gene to hypertension and serum cholesterol in Japanese workers
T Sawada, T Kishimoto, Y Osaki, M Okamoto, A Tahara, A Kaetu, ...
Preventive medicine 47 (2), 167-171, 2008
242008
Generation of four postmortem dura-derived iPS cell lines from four control individuals with genotypic and brain-region-specific transcriptomic data available through the …
T Sawada, KJM Benjamin, AC Brandtjen, E Tietze, SJ Allen, ...
Stem cell research 46, 101806, 2020
52020
Single-cell analysis of human trophoblast stem cell specification reveals activation of fetal cytotropho-blast expression programs including coronavirus associated host factors …
E Tietze, AR Barbosa, V Euclydes, HJ Cho, YK Lee, A Feltrin, ...
bioRxiv, 2020
22020
Human archetypal pluripotent stem cells differentiate into trophoblast stem cells via endogenous BMP5/7 induction without transitioning through naive state
E Tietze, AR Barbosa, B Araujo, V Euclydes, B Spiegelberg, HJ Cho, ...
Scientific Reports 14 (1), 1-15, 2024
2024
Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donor’s Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia
T Sawada, AR Barbosa, B Araujo, AE McCord, L D’Ignazio, ...
American Journal of Psychiatry, appi. ajp. 20220723, 2023
2023
Variation in TAF1 expression in female carrier induced pluripotent stem cells and human brain ontogeny has implications for adult neostriatum vulnerability in X-linked Dystonia …
EJA D'Ignazio L, Jacomini RS, Qamar B, Benjamin KJM, Arora R, Sawada T ...
eNeuro 9 (4), ENEURO.0129-22.2022., 2022
2022
Ventral forebrain organoids derived from individuals with schizophrenia recapitulate perturbed striatal gene expression dynamics of the donor’s brains
T Sawada, A Barbosa, B Araujo, AE McCord, L D’Ignazio, KJM Benjamin, ...
bioRxiv, 2022.05. 26.493589, 2022
2022
A single cell trajectory of human archetypal pluripotent stem cell differentiation to trophoblast stem cells reveals induction of endogenous BMP5/7 and GATA3 without …
E Tietze, AR Barbosa, BH Silva Araujo, V Euclydes, HJ Cho, YK Lee, ...
bioRxiv, 2020.08. 29.273425, 2020
2020
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