| A clinical-pharmacological evaluation of hepatic arterial infusions of 5-fluoro-2′-deoxyuridine and 5-fluorouracil WD Ensminger, A Rosowsky, V Raso, DC Levin, M Glode, S Come, ... Cancer research 38 (11_Part_1), 3784-3792, 1978 | 657 | 1978 |
| Characterization of a Human Squamous Carcinoma Cell Line Resistant to cis-Diamminedichloroplatinum(II) BA Teicher, SA Holden, MJ Kelley, TC Shea, CA Cucchi, A Rosowsky, ... Cancer Research 47 (2), 388-393, 1987 | 392 | 1987 |
| Carrier-and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity. GR Westerhof, JH Schornagel, I Kathmann, AL Jackman, A Rosowsky, ... Molecular pharmacology 48 (3), 459-471, 1995 | 303 | 1995 |
| Cyclophosphamide pharmacokinetics: correlation with cardiac toxicity and tumor response. LJ Ayash, JE Wright, O Tretyakov, R Gonin, A Elias, C Wheeler, JP Eder, ... Journal of Clinical Oncology 10 (6), 995-1000, 1992 | 242 | 1992 |
| Alkylating Agents: In Vitro Studies of Cross-Resistance Patterns in Human Cell Lines BA Teicher, CA Cucchi, JB Lee, JL Flatow, A Rosowsky, E Frei III Cancer Research 46 (9), 4379-4383, 1986 | 210 | 1986 |
| Alkylating agent resistance: in vitro studies with human cell lines. E Frei 3rd, CA Cucchi, A Rosowsky, R Tantravahi, S Bernal, TJ Ervin, ... Proceedings of the National Academy of Sciences 82 (7), 2158-2162, 1985 | 166 | 1985 |
| Continuous infusion high-dose leucovorin with 5-fluorouracil and cisplatin for untreated stage IV carcinoma of the head and neck AI Dreyfuss, JR Clark, JE Wright, CM Norris Jr, PM Busse, JW Lucarini, ... Annals of Internal medicine 112 (3), 167-172, 1990 | 152 | 1990 |
| Structural features of 5, 10-dideaza-5, 6, 7, 8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferase SW Baldwin, A Tse, LS Gossett, EC Taylor, A Rosowsky, C Shih, ... Biochemistry 30 (7), 1997-2006, 1991 | 143 | 1991 |
| Synthesis and antifolate activity of 2,4‐diamino‐5,6,7,8‐tetrahydropyrido[4,3‐d]pyrimidine analogues of trimetrexate and piritrexim A Rosowsky, CE Mota, SF Queener Journal of heterocyclic chemistry 32 (1), 335-340, 1995 | 126 | 1995 |
| Structural features of 4-amino antifolates required for substrate activity with mammalian folylpolyglutamate synthetase RG Moran, PD Colman, A Rosowsky, RA Forsch, KK Chan Mol Pharmacol 27 (1), 156-166, 1985 | 119 | 1985 |
| Effects of methotrexate esters and other lipophilic antifolates on methotrexate-resistant human leukemic lymphoblasts A Rosowsky, H Lazarus, GC Yuan, WR Beltz, L Mangini, HT Abelson, ... Biochemical pharmacology 29 (4), 648-652, 1980 | 118 | 1980 |
| A phase I and pharmacokinetic study of a new camptothecin derivative, 9-aminocamptothecin. E Rubin, V Wood, A Bharti, D Trites, C Lynch, S Hurwitz, S Bartel, S Levy, ... Clinical cancer research: an official journal of the American Association …, 1995 | 117 | 1995 |
| Synthesis of new 2, 4-diaminopyrido [2, 3-d] pyrimidine and 2, 4-diaminopyrrolo [2, 3-d] pyrimidine inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium … A Rosowsky, H Chen, H Fu, SF Queener Bioorganic & medicinal chemistry 11 (1), 59-67, 2003 | 105 | 2003 |
| Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia LH Matherly, JW Taub, Y Ravindranath, SA Proefke, SC Wong, P Gimotty, ... | 103 | 1995 |
| Defective transport as a mechanism of acquired resistance to methotrexate in patients with acute lymphocytic leukemia T Trippett, S Schlemmer, Y Elisseyeff, E Goker, M Wachter, P Steinherz, ... | 101 | 1992 |
| Methotrexate analogs. 14. Synthesis of new. gamma.-substituted derivatives as dihydrofolate reductase inhibitors and potential anticancer agents A Rosowsky, R Forsch, J Uren, M Wick Journal of Medicinal Chemistry 24 (12), 1450-1455, 1981 | 99 | 1981 |
| Synthesis and biological activity of L-5-deazafolic acid and L-deazaaminopterin: synthetic strategies to 5-deazapteridines EC Taylor, DC Palmer, TJ George, SR Fletcher, CP Tseng, PJ Harrington, ... The Journal of Organic Chemistry 48 (25), 4852-4860, 1983 | 94 | 1983 |
| 2, 4-Diaminothieno [2, 3-d] pyrimidine analogs of trimetrexate and piritrexim as potential inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase A Rosowsky, CE Mota, JE Wright, JH Freisheim, JJ Heusner, ... Journal of medicinal chemistry 36 (21), 3103-3112, 1993 | 92 | 1993 |
| Development of methotrexate resistance in a human squamous cell carcinoma of the head and neck in culture. E Frei 3rd, A Rosowsky, JE Wright, CA Cucchi, JA Lippke, TJ Ervin, ... Proceedings of the National Academy of Sciences 81 (9), 2873-2877, 1984 | 88 | 1984 |
| Human thymidylate synthetase—III: effects of methotrexate and folate analogs DW Szeto, C Yung-Chi, A Rosowsky, Y Cheng-Sein, EJ Modest, JR Piper, ... Biochemical pharmacology 28 (17), 2633-2637, 1979 | 88 | 1979 |
