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George M.H. Birchenough
George M.H. Birchenough
Assistant Professor, University of Gothenburg
Verified email at gu.se - Homepage
Title
Cited by
Cited by
Year
The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system
T Pelaseyed, JH Bergström, JK Gustafsson, A Ermund, GMH Birchenough, ...
Immunological reviews 260 (1), 8-20, 2014
12322014
New developments in goblet cell mucus secretion and function
GMH Birchenough, MEV Johansson, JK Gustafsson, JH Bergström, ...
Mucosal immunology 8 (4), 712-719, 2015
7152015
Bifidobacteria or fiber protects against diet-induced microbiota-mediated colonic mucus deterioration
BO Schroeder, GMH Birchenough, M Ståhlman, L Arike, MEV Johansson, ...
Cell host & microbe 23 (1), 27-40. e7, 2018
5962018
A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion
GMH Birchenough, EEL Nyström, MEV Johansson, GC Hansson
Science 352 (6293), 1535-1542, 2016
5302016
Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis
S van der Post, KS Jabbar, G Birchenough, L Arike, N Akhtar, H Sjovall, ...
Gut 68 (12), 2142-2151, 2019
3252019
An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function
EEL Nyström, B Martinez-Abad, L Arike, GMH Birchenough, EB Nonnecke, ...
Science 372 (6539), eabb1590, 2021
1722021
Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16
JH Bergström, GMH Birchenough, G Katona, BO Schroeder, A Schütte, ...
Proceedings of the National Academy of Sciences 113 (48), 13833-13838, 2016
1432016
The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function
JK Volk, EEL Nyström, S van der Post, BM Abad, BO Schroeder, ...
Journal of Experimental Medicine 216 (11), 2602-2618, 2019
912019
Hypervirulent Clostridium difficile PCR-ribotypes exhibit resistance to widely used disinfectants
LF Dawson, E Valiente, EH Donahue, G Birchenough, BW Wren
PloS one 6 (10), e25754, 2011
832011
Dietary destabilisation of the balance between the microbiota and the colonic mucus barrier
G Birchenough, BO Schroeder, F Bäckhed, GC Hansson
Gut Microbes 10 (2), 246-250, 2019
802019
Calcium-activated chloride channel regulator 1 (CLCA1) controls mucus expansion in colon by proteolytic activity
EEL Nyström, GMH Birchenough, S van der Post, L Arike, AD Gruber, ...
EBioMedicine 33, 134-143, 2018
802018
Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli
GMH Birchenough, MEV Johansson, RA Stabler, F Dalgakiran, ...
Infection and immunity 81 (9), 3264-3275, 2013
442013
Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice
BO Schroeder, GMH Birchenough, M Pradhan, EEL Nyström, ...
Journal of Biological Chemistry 295 (46), 15712-15726, 2020
352020
The goblet cell protein Clca1 (alias mClca3 or Gob-5) is not required for intestinal mucus synthesis, structure and barrier function in naive or DSS-challenged mice
NA Erickson, EEL Nyström, L Mundhenk, L Arike, R Glauben, ...
PLoS One 10 (7), e0131991, 2015
322015
Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1
A Zelmer, MJ Martin, O Gundogdu, G Birchenough, R Lever, BW Wren, ...
Microbiology 156 (7), 2205-2215, 2010
322010
NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation
S van der Post, GMH Birchenough, JM Held
Cell reports 35 (1), 2021
312021
Functional mucous layer and healing of proximal colonic anastomoses in an experimental model
J Bosmans, A Jongen, GMH Birchenough, EEL Nyström, MJJ Gijbels, ...
Journal of British Surgery 104 (5), 619-630, 2017
272017
Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer
JDA Sharpen, B Dolan, EEL Nyström, GMH Birchenough, L Arike, ...
Nature Communications 13 (1), 45, 2022
232022
Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection
GMH Birchenough, F Dalgakiran, LA Witcomb, MEV Johansson, ...
Scientific reports 7 (1), 83, 2017
232017
Non-invasive model of neuropathogenic Escherichia coli infection in the neonatal rat
F Dalgakiran, LA Witcomb, AJ McCarthy, GMH Birchenough, PW Taylor
JoVE (Journal of Visualized Experiments), e52018, 2014
232014
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